Certara’s Post

#QPS excels at drug metabolism and pharmacokinetics (#DMPK) #preclincal research. These important studies shed light on how our bodies process medications. Visit https://bit.ly/3qHjkIo for more details, or email us at info@qps.com to get your study started. #pharmacokinetics #CRO

Investigation of the in vivo pharmacokinetic (PK) properties plays a very important role in the drug candidate’s success before entering clinical trials. The pharmacokinetics of a drug compound can be evaluated by conducting a study to determine in vivo PK parameters, which can be used for compound ranking and for  revealing undesired PK properties such as rapid metabolism or poor bioavailability, which can lead to termination of the development project.   To learn more about these studies available for all drug modalities, download this free fact sheet https://lnkd.in/dTaBD6aG Admescope a Symeres company   #Admescope #Symeres #PKscreening #Pharmacokinetics #InVivoPK #drugdevelopment #MakingMoleculesMatter

I am thrilled to announce that I completed the course of Pharmacokinetics by Novartis. This course summerized the concepts of pharmacokinetics (PK), ADME (Absorption, Distribution, Metabolism, and Excretion), volume of distribution, half life and elimination. Differences between different route of administration and their impact on PK parameters. Difined and described the influence of transporters, plasma protein binding (PPB) and drug drug interactions (DDI) on the PK of a drug molecule. Explained how PK/PD relationships are derived and their importance for defining the anticipated human dose. I am excited to apply these new skills and insight to real-world projects and continue exploring the fantastic world of clinical trials. #HealthCare #Pharmacy #Novartis #Coursera #ClinicalTrials #Pharmacokinetics #Pharmacodynamics #PK #PD #ADME #DDI #PPB

Respiratory drug development demands a comprehensive understanding of both the drug's Pharmacokinetics and Pharmacodynamic nature. One of the primary roles of CROs is to design tailored methodologies for bioanalysis and collaborating closely with pharma and biopharma companies to develop and validate robust bioanalytical methods. Tune in to our latest video presentation, as we explore and address the five key challenges in method development and validation of Fluticasone Propionate and our experience with different molecules in the field of Respiratory , such as Salmeterol, Formoterol, Tiotropium, Budesonide, and more.   To know more about our Respiratory drug-development Capabilities write to us at info@veedacr.com Partners in creating a healthier tomorrow. #Veeda #VeedaClinicalResearch #VeedaCR #DrugDevelopment #RespiratoryDrug #CRO #Bioanalysis #Respiratory

Drug-drug Interactions (DDI) are an inevitable by-product of polypharmacy. DDIs can be divided into pharmacokinetic and pharmacodynamic interactions. Current regulatory guidance is focused on pharmacokinetic interactions. It is important to understand the underlying mechanics and differences between enzyme inhibition subtypes to be able to set up proper incubation methods and to interpret the results correctly.   Our e-book on Drug-drug Interactions will introduce you inhibition kinetics along with a comparison between the enzyme sources most often used in CYP inhibition studies. Enzyme induction is addressed in the book from CYP point-of-view as CYP induction is the most studied form of induction in drug metabolism and is required by regulatory authorities. The book also covers in vitro to in vivo extrapolation of CYP inhibition and induction, and familiarizes readers to different types of models used for DDI prediction. You can download your free copy of this helpful resource here: https://lnkd.in/dbnihjEz Admescope a Symeres company #Admescope #Symeres #DDI #drugdruginteractions #polypharmacy #CYP450 #drugdiscovery

The #published article on our #Pharmaceuticals A #Protein-Based, Long-Acting #HIV-1 Fusion #Inhibitor with an Improved #Pharmacokinetic Profile by Xu et al. Enjoy reading: https://lnkd.in/g8VVRBbx

#clientssay 𝗔𝗰𝗰𝗲𝗹𝗲𝗿𝗮𝘁𝗲 𝘆𝗼𝘂𝗿 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝘄𝗶𝘁𝗵 𝗥𝗲𝗹𝗶𝗮𝗯𝗹𝗲 𝗦𝗲𝗿𝘃𝗶𝗰𝗲! 𝗪𝗲’ 𝗿𝗲 𝘁𝗵𝗿𝗶𝗹𝗹𝗲𝗱 𝘁𝗼 𝗵𝗲𝗮𝗿 𝘀𝘂𝗰𝗵 𝗮𝗺𝗮𝘇𝗶𝗻𝗴 𝗳𝗲𝗲𝗱𝗯𝗮𝗰𝗸! 𝗧𝗵𝗮𝗻𝗸 𝘆𝗼𝘂 𝗳𝗼𝗿 𝘁𝗮𝗸𝗶𝗻𝗴 𝘆𝗼𝘂𝗿 𝘁𝗶𝗺𝗲 𝘁𝗼 𝘀𝗵𝗮𝗿𝗲 𝗲𝘅𝗽𝗲𝗿𝗶𝗲𝗻𝗰𝗲 𝘄𝗶𝘁𝗵 𝗚𝗲𝗻𝗦𝗰𝗿𝗶𝗽𝘁. 𝗔𝘁 𝗚𝗲𝗻𝗦𝗰𝗿𝗶𝗽𝘁, 𝘄𝗲 𝗹𝗲𝘃𝗲𝗿𝗮𝗴𝗲 𝗼𝘂𝗿 𝗲𝘅𝘁𝗲𝗻𝘀𝗶𝘃𝗲 𝗲𝘅𝗽𝗲𝗿𝗶𝗲𝗻𝗰𝗲, 𝘀𝘁𝗮𝘁𝗲-𝗼𝗳-𝘁𝗵𝗲-𝗮𝗿𝘁 𝗶𝗻𝗳𝗿𝗮𝘀𝘁𝗿𝘂𝗰𝘁𝘂𝗿𝗲, 𝗮𝗻𝗱 𝗲𝗻𝗱-𝘁𝗼-𝗲𝗻𝗱 𝘀𝗼𝗹𝘂𝘁𝗶𝗼𝗻𝘀 𝘁𝗼 𝘂𝗻𝗹𝗼𝗰𝗸 𝘁𝗵𝗲 𝗳𝘂𝗹𝗹 𝗽𝗼𝘁𝗲𝗻𝘁𝗶𝗮𝗹 𝗼𝗳 𝘆𝗼𝘂𝗿 𝗽𝗿𝗼𝗷𝗲𝗰𝘁𝘀. 𝗧𝗿𝘂𝘀𝘁𝗲𝗱 𝗣𝗲𝗽𝘁𝗶𝗱𝗲 - Our commitment to excellence is unwavering. We provide thoroughly researched and rigorously tested products, ensuring your confidence with every purchase. 𝗘𝘅𝗰𝗲𝗹𝗹𝗲𝗱 𝗦𝗲𝗿𝘃𝗶𝗰𝗲 - Our dedicated team is passionate about delivering personalized service that goes above and beyond. From expert advice to prompt delivery, we ensure a seamless and satisfying experience. Ready to experience the GenScript difference? Connect with us today for peptide synthesis that's as quick as your discoveries! Visit 👉https://ow.ly/SMBA50SxChl for more info. Key Service available: ✅ cGMP Peptide Synthesis https://ow.ly/IajJ50SxChn ✅ Neoantigen Peptide Synthesis and Process Development https://ow.ly/SVpe50SxCho ✅ GLP-1 Receptor Agonist Services for Type 2 Diabetes and Obesity Drug Development https://ow.ly/QuVu50SxChm #GenScript #PeptideSynthesis #SpeedyScience #ReliableResults #ClientPraise #ResearchRevolution #TrustedPeptide #ExcelledService

📢 Rebooting the "Small Molecule Highlights" Series! 🚀 Excited to announce the revival of our well-received blog series after a rejuvenating summer hiatus. Immerse yourself in fresh insights from 6 carefully selected small molecules, thoughtfully curated from the latest drug discovery literature. Allow us to introduce our new voice, 👨🔬David Rosa, Ph.D., Senior Scientist at Dalriada Drug Discovery. These compounds are aimed at diverse targets - DLK, FXR, FLT3, AR, PKM2, and AcrAB-TolC. Dive into the full article here➡️https://lnkd.in/gM69b6xr #medicinalchemistry #drugdesign #drugdiscovery #drughunter #pharma #biotech #healthcare #medicine #pharmacology #smallmolecules

Look who it is! 📸 Today is the last day of the CPhI North America Conference in Philadelphia. Connect with our Phase 1 & Bioequivalence Expert Mo H. on the event floor before you miss out! Want to understand BioPharma Services Inc. capabilities in supporting your next drug development project? Shoot Mo a connection and get chatting. BioPharma Services Inc. specializes in Phase 1 clinical trials, bioequivalence, bioavailability, First-in-Human and Human Abuse Potential Studies (#HAP). Let our world-renowned #Pharmacokinetics team execute your next clinical trial with confidence. . . . #biopharma #clinicalresearch #clinicalstudies #clinicaltrials #bioanalytics #cphi #cphinorthamerica #bioequivalence #generics

BIONOTUS obtained the GLP CERTIFICATE for Bioanalysis and PK/PD.  This achievement turns BioNotus into a one-stop-shop for bioanalysis from drug discovery to preclinical in vivo animal tox and clinical phase I-IV, a clear advantage for our customers in terms of time and cost efficiency. Preclinical and clinical in vivo phases are covered through local partnerships. #GLP, #preclinical, #clinical, #drugdevelopment, #pharmacometrics, #pharmacokinetics, #toxicokinetics, #pharmacodynamics, #bioanalysis, #CRO, #drugsafety, #LCMS, #massspectrometry, #modelingandsimulation, #quantitativepharmacology, #ADME, #MetID, #PKSIM, #mobi, #NONMEM, #Certara, #Sciex, #PKmodeling, #PKPD, #PBPK