CinRx Pharma’s Post

During the last fifteen years, UPMC has treated more than 1,200 cases of thoracic #aortic dissections (TAD) and is one of the leading research centers in the U.S. studying the pathophysiology of the disorder while also publishing on its institutional outcomes, notably on the role malperfusion syndrome plays in TAD and how to optimally manage patient care. Ibrahim Sultan, MD, FACS, FACC, further discusses some of the insights, treatment approaches, and research learnings from UPMC in caring for patients with TAD in this new article: https://lnkd.in/eyVhMzDF

It is an honor to be part of an amazing team. Thank you for your support! Beyond excited to share my first-ever first author paper published in Brain Research! 🧠🎉 If you are interested in #impulsivity, reward value and #pain, find out more on these topics here:

Hyungbae Kwon, Ph.D., and colleagues have successfully used optogenetics to artificially reactivate a spatial-memory, prompting shelter-seeking behavior in mice without the original threatening stimuli that were present during the formation of the memory circuit. Their study advances our understanding of mammalian spatial-memory structure and formation. “If we understand the macro-level structure of memory, then we may be able to develop more effective strategies to prevent or slow down neurodegenerative diseases using this method,” says Hyungbae Kwon, Ph.D.  Full article: https://lnkd.in/gvwbZfuQ Johns Hopkins Medicine The Johns Hopkins University

Much deeply thoughtful and studied science around the chemistry, physiology and the psychology of pain. There are some wonderful and promising research at the 2nd Annual NIH HEAL symposium here at the Maryland Gaylord Convention Center. After many years of research, it is still a challenging area of human experience to try to put a finger on safer solutions for pain. Yet, sometimes complex problems can be answered with simple solutions. That is the goal of H3Pelvic Therapy Systems, providing better, safer, and much more dignified patient improving outcomes. H3Pelvic, bringing dignity back to healthcare and giving chronic pelvic pain victims renewed hope.

In this webinar, I had the chance to address several frequently asked patient inquiries about atrial fibrillation. We discussed heart rhythm monitoring, left atrial appendage occlusion as a potential strategy for lowering stroke risk in certain patients, explored the influence of the autonomic nervous system on the development of atrial fibrillation, and covered the importance of lifestyle changes. For more atrial fibrillation resources and to subscribe for updates, please visit https://linktr.ee/ykhaykin #AtrialFibrillation #AFibAblation #CatheterAblation #Electrophysiology #AFibCare #HeartHealth #StrokePrevention #AFibAwareness #AFibManagement #AFibTreatmentOptions #Cardiology #PatientCare #RecoveryTips #HeartRhythmMonitoring #WearableTech #CardiacMonitoring #DigitalHealth #RemoteMonitoring #ECGMonitoring #HolterMonitor #PatientMonitoring #CardiacElectrophysiology #ArrhythmiaManagement #HeartElectrophysiology #CardiacArrhythmias #EPProcedures

🔬 Explore the Astonishing World of Medical Discovery with Prof. Dr Dr Ernst R von Schwarz 💡 Transport back to his days as a medical student, where a lecture by the illustrious hepatologist, Popper, at the University of Göttingen, Germany, uncovered the liver's hidden treasures. 🌟 From the renowned Viennese Popper family, he revealed the liver's vast store of stem cells, a testament to its innate ability to regenerate and heal. Let's delve through the wonders of science and witness the body's incredible resilience! 💫 💡 Click the link in our bio for more stories on wellness! #TransformWellnessTogether #AIWellness #healthcare #healthandwellness #MedicalDiscovery #LiverRegeneration #ScienceAwakening 🔬

Our recent research, titled "Exploring the Underlying Mechanisms of Ischemic Heart Disease Post-Stroke: Insights from a 2-Year Follow-Up Investigation," has been published in the Annals of Gerontology and Geriatric Research! This paper addresses a critical gap in current research by extending the temporal scope of risk prediction models, emphasizing the importance of considering a 2-year follow-up period for patients with ischemic stroke in the ICU. The utilization of machine learning techniques underscores a commitment to innovative and data-driven approaches in healthcare, with the ultimate goal of improving patient outcomes and refining clinical decision-making in this specific medical context. A heartfelt thank you to the dedicated team, collaborators, and everyone involved in making this research a reality. Your contributions are invaluable! 📚 Read the Full Paper https://lnkd.in/gEmHGJTh #Research #Cardiology #Geriatrics #Stroke #HeartDisease #AcademicPublishing #MedicalResearch #Science #HealthInsights

🌟 I am happy to publish this comprehensive review on #ocular changes in #cysticfibrosis in the International Journal of Molecular Sciences MDPI (https://lnkd.in/dRyW8fuW). This is a collaborative work between the Departments of #Ophthalmology at Poznan University of Medical Sciences - Prof. Jaroslaw Kociecki and Dr. Slawomir Liberski, Humanitas University - Dr. Filippo Confalonieri, and myself at the University of Oslo and Oslo University Hospital. The study explores the impact of cystic fibrosis on eye health, highlighting important findings that can enhance our understanding of this complex condition. Early #detection and #management of ocular #complications are crucial for improving the #quality_of_life for individuals with cystic fibrosis. #CysticFibrosis #OcularHealth #ResearchReview 📚🔬

Rehabilitation interventions are complex and studying their effectiveness is methodologically challenging. In our new paper in the European Journal of Physical and Rehabilitation Medicine (part of a series from Cochrane Rehabilitation), we offer an alternative to the randomized control trial when it cannot be conducted. We discuss how the Target Trial Emulation framework can be used to study the effectiveness of rehabilitation interventions. https://lnkd.in/gvhVQkBr

#CysticFibrosis is a debilitating and devastating #respiratory disease. One of the leading lights in #CF research is Prof. David Sheppard’s lab at the University of Bristol. The Sheppard lab recently published seminal research characterizing the reduced chloride conductance in two rare #CFTR mutant channels (S1159F and S1159P) that lead to cystic fibrosis. Reflecting on this study in the context of the great advances in CF, Prof. Sheppard notes: “𝘈𝘴 𝘵𝘩𝘦 Cystic Fibrosis Trust 𝘮𝘢𝘳𝘬𝘴 𝘪𝘵𝘴 60𝘵𝘩 𝘢𝘯𝘯𝘪𝘷𝘦𝘳𝘴𝘢𝘳𝘺, 𝘪𝘵 𝘪𝘴 𝘢𝘱𝘱𝘳𝘰𝘱𝘳𝘪𝘢𝘵𝘦 𝘵𝘰 𝘳𝘦𝘧𝘭𝘦𝘤𝘵 𝘰𝘯 𝘵𝘩𝘦 𝘱𝘳𝘰𝘨𝘳𝘦𝘴𝘴 𝘮𝘢𝘥𝘦 𝘵𝘰𝘸𝘢𝘳𝘥𝘴 𝘥𝘦𝘭𝘪𝘷𝘦𝘳𝘪𝘯𝘨 𝘵𝘩𝘦 𝘣𝘦𝘴𝘵 𝘱𝘰𝘴𝘴𝘪𝘣𝘭𝘦 𝘤𝘢𝘳𝘦 𝘧𝘰𝘳 𝘱𝘦𝘰𝘱𝘭𝘦 𝘸𝘪𝘵𝘩 𝘤𝘺𝘴𝘵𝘪𝘤 𝘧𝘪𝘣𝘳𝘰𝘴𝘪𝘴.  𝘌𝘷𝘪𝘥𝘦𝘯𝘤𝘦-𝘣𝘢𝘴𝘦𝘥 𝘮𝘦𝘥𝘪𝘤𝘪𝘯𝘦 𝘩𝘢𝘴 𝘭𝘦𝘥 𝘵𝘰 𝘱𝘳𝘰𝘨𝘳𝘦𝘴𝘴𝘪𝘷𝘦 𝘪𝘮𝘱𝘳𝘰𝘷𝘦𝘮𝘦𝘯𝘵𝘴 𝘪𝘯 𝘵𝘩𝘦 𝘩𝘦𝘢𝘭𝘵𝘩 𝘰𝘧 𝘱𝘦𝘰𝘱𝘭𝘦 𝘸𝘪𝘵𝘩 𝘤𝘺𝘴𝘵𝘪𝘤 𝘧𝘪𝘣𝘳𝘰𝘴𝘪𝘴, 𝘸𝘩𝘪𝘭𝘦 𝘦𝘭𝘦𝘹𝘢𝘤𝘢𝘧𝘵𝘰𝘳-𝘵𝘦𝘻𝘢𝘤𝘢𝘧𝘵𝘰𝘳-𝘪𝘷𝘢𝘤𝘢𝘧𝘵𝘰𝘳 𝘩𝘢𝘴 𝘵𝘳𝘢𝘯𝘴𝘧𝘰𝘳𝘮𝘦𝘥 𝘵𝘩𝘦 𝘰𝘶𝘵𝘭𝘰𝘰𝘬 𝘧𝘰𝘳 𝘮𝘢𝘯𝘺, 𝘣𝘶𝘵 𝘯𝘰𝘵 𝘢𝘭𝘭 𝘱𝘦𝘰𝘱𝘭𝘦 𝘸𝘪𝘵𝘩 𝘤𝘺𝘴𝘵𝘪𝘤 𝘧𝘪𝘣𝘳𝘰𝘴𝘪𝘴. 𝘛𝘩𝘪𝘴 𝘪𝘯𝘤𝘦𝘯𝘵𝘪𝘷𝘪𝘴𝘦𝘴 𝘵𝘩𝘦 𝘤𝘺𝘴𝘵𝘪𝘤 𝘧𝘪𝘣𝘳𝘰𝘴𝘪𝘴 𝘤𝘰𝘮𝘮𝘶𝘯𝘪𝘵𝘺 𝘵𝘰 𝘥𝘰 𝘮𝘰𝘳𝘦, 𝘲𝘶𝘪𝘤𝘬𝘦𝘳 𝘵𝘰 𝘣𝘳𝘪𝘯𝘨 𝘭𝘪𝘧𝘦-𝘤𝘩𝘢𝘯𝘨𝘪𝘯𝘨 𝘵𝘩𝘦𝘳𝘢𝘱𝘪𝘦𝘴 𝘵𝘰 𝘢𝘭𝘭 𝘱𝘦𝘰𝘱𝘭𝘦 𝘸𝘪𝘵𝘩 𝘤𝘺𝘴𝘵𝘪𝘤 𝘧𝘪𝘣𝘳𝘰𝘴𝘪𝘴. 𝘐 𝘢𝘮 𝘦𝘴𝘱𝘦𝘤𝘪𝘢𝘭𝘭𝘺 𝘨𝘳𝘢𝘵𝘦𝘧𝘶𝘭 𝘵𝘰 𝘮𝘺 𝘤𝘰𝘭𝘭𝘦𝘢𝘨𝘶𝘦𝘴 𝘱𝘢𝘴𝘵 𝘢𝘯𝘥 𝘱𝘳𝘦𝘴𝘦𝘯𝘵 𝘧𝘰𝘳 𝘵𝘩𝘦𝘪𝘳 𝘤𝘰𝘮𝘮𝘪𝘵𝘮𝘦𝘯𝘵 𝘢𝘯𝘥 𝘥𝘦𝘥𝘪𝘤𝘢𝘵𝘪𝘰𝘯 𝘵𝘰 𝘤𝘺𝘴𝘵𝘪𝘤 𝘧𝘪𝘣𝘳𝘰𝘴𝘪𝘴 𝘳𝘦𝘴𝘦𝘢𝘳𝘤𝘩 𝘢𝘯𝘥 𝘵𝘩𝘦 𝘊𝘺𝘴𝘵𝘪𝘤 𝘍𝘪𝘣𝘳𝘰𝘴𝘪𝘴 𝘛𝘳𝘶𝘴𝘵 𝘧𝘰𝘳 𝘧𝘶𝘯𝘥𝘪𝘯𝘨 𝘰𝘶𝘳 𝘸𝘰𝘳𝘬” Congratulations to Dr. Hongyu Li and collaborators on this groundbreaking study. To learn more, click here: https://lnkd.in/dhRyaEKj #CFT #translationalscience #RespiratoryDisease #Qube384 #QPatchCompact #AutomatedPatchClamp #DrugDiscovery #Electrophysiology #Sophion