Cyagen’s Post

Video - NCM 2023 Houston: Building and applying global pathogen surveillance in a post/peri-pandemic world APHL Global Health leverages next-generation sequencing (NGS), bioinformatics, and genomic epidemiology to enhance public health decision-making in 78 countries. NGS emerged as a crucial component of the COVID-19 pandemic response, with internal and external investments catalyzing advancements in global pathogen genomic capabilities. We emphasize establishing regional capacities in a post/peri-pandemic setting, enabling real-time technical support. A fundamental principle is prioritizing a south-to-south global approach, fostering collaboration among nations with similar challenges. Crucially, we aim to assess the costs of pathogen genomics initiatives, ensuring their long-term sustainability. Exploring diverse use cases demonstrates the broad impact of pathogen genomics on public health outcomes, attracting funding from various entities. While the COVID-19 pandemic brought enduring challenges, it accelerated global pathogen genomics by a decade. APHL seeks to harness this momentum by showcasing the transformative potential of NGS technology, bioinformatics, genomic epidemiology, and data visualization, fostering better health outcomes at individual and population levels https://lnkd.in/d33GUHFJ

This is a great blog post on the importance of data and contextual metadata. It challenges the idea of universally "bad data" and emphasizes the importance of structure and context for scientific and public health interpretation. #PublicHealth #Bioinformatics #PHA4GE #PathogenGenomics #metadata #AdvancedMolecularDetection #PublicHealth #MicrobiologySociety

In the dynamic world of molecular diagnostics, real-time PCR has become a cornerstone technique. Its ability to detect and quantify genetic material with high precision is invaluable in clinical settings, research, and even epidemiology. From infectious diseases to oncology and genetics, this technology empowers us to find the answers we need in a matter of hours. But as powerful as real-time PCR is, the full potential of this technology is unlocked when it is implemented seamlessly. This is where the role of an Application Specialist comes into play. As an Application Specialist at 3B BlackBio Dx Limited for the past 3 years, my focus has been to make this cutting-edge technology accessible and user-friendly to all end-users. For me, it is not just about demonstrating the kit; it's about ensuring that the learning process is engaging and simplified. Whether it’s troubleshooting a complex issue or supporting users in the field, my aim is to build trust in our service and products while fostering lasting relationships. In the end, the real significance of my role lies in empowering healthcare professionals to use our real-time PCR kits confidently and effectively to make faster, more informed decisions—saving time, and potentially lives. #RealTimePCR #MolecularDiagnostics #HealthcareInnovation #CustomerSupport #techsupport #ApplicationsSpecialist

Within the medical community, the diagnosis and treatment of rare diseases, like ALSP, are often hindered by a complex array of symptoms and patient-specific presentation of such symptoms. This complexity requires an increased awareness throughout the medical community and a collaborative approach across disciplines for effective management. Genetic testing serves as an accurate and effective tool, especially for conditions such as ALSP that stem from genetic mutations. It offers the most direct and reliable route to diagnosis, facilitating a better understanding of disease epidemiology and clearing the path for patients to connect with the medical experts dedicated to advancing treatment and cure research. - #RareDisease #Medical #Genetics

📣 Precision Medicine Diversity Array Promotion Take advantage of our limited-time offer on the Applied Biosystems™ Axiom™ Precision Medicine Diversity Array (PMDA), now available at R1200.00 per sample (excluding DNA extraction and analysis, VAT inclusive). This state-of-the-art microarray provides advanced insights into genetic factors crucial for disease research, genetic testing, and more! 💡 Why Choose Our PMDA+PGx Microarray? 🔹Designed for diverse global populations 🔹Coverage of complex disease susceptibility, pharmacogenomics (PGx), & population genomics 🔹Ideal for both clinical and research applications in personalized medicine, drug response, and disease risk 👩🔬 Who Can Benefit? 🔹Pharmacogenetic researchers looking to advance drug response studies 🔹Epidemiologists exploring genetic risk factors in population health 🔹Healthcare professionals interested in personalized medicine solutions 🔹Population geneticists studying genomic diversity and complex disease risk 📅 Limited Time Offer – Register a project with us before 30th October 2024 to secure this promotional pricing. 🔗 Apply here: https://lnkd.in/dtABFgEf #cpgr #Pharmacogenomics #PrecisionMedicine #Genomics #PopulationGenomics #PersonalizedHealthcare #Epidemiology #PMDA #CPGR #OMICS #WCE2024 #PublicHealth

"Nearly four years since the pandemic emerged, people are growing weary of dealing with it, but the virus is not done with us. Nationally, a sharp uptick in emergency room visits and hospitalizations for COVID-19, influenza, and respiratory syncytial virus, or RSV, began in mid-December and appears to be gaining momentum," reports CBS News. Investigating the role of host genetic factors in COVID-19 severity and susceptibility can inform our understanding of the underlying biological mechanisms that influence adverse outcomes and drug development. Here we present a second updated genome-wide association study (GWAS) on COVID-19 severity and infection susceptibility to SARS-CoV-2 from the COVID-19 Host Genetic Initiative. We performed a meta-analysis of up to 219,692 cases and over 3 million controls, identifying 51 distinct genome-wide significant loci— adding 28 loci from the previous data release. The increased number of candidate genes at the identified loci helped to map three major biological pathways that are involved in susceptibility and severity: viral entry, airway defence in mucus and type I interferon. We have substantially expanded the current knowledge of host genetics for COVID-19 susceptibility and severity. Further investigation of how such susceptibility and severity loci map to different pathways would provide mechanistic insights into the human genetic architecture of COVID-19. Read our full research paper on mapping the human genetic architecture of COVID-19 here: https://lnkd.in/gVNzauvf #research #science #researchmethods #researchreport #researchpaper #covid #covid19 #covid19pandemic #covid19research #sarscov2 #respiratoryvirus #respiratory #respiratoryprotection #respiratoryhealth #respiratorycare #genetics #dna #genes #humangenetics #humanhealth #geneticresearch #genomics #genome #genomicresearch #preventivegenomics #translationalgenomics #medicine #investigadtion #biologicalpathways #biology #biotechnology #biomedical #precisionmedicine #genomicmedicine #preventivemedicine #preventivecare #prevention #health #precisionhealth #preventivehealth #publichealth #newbornhealth #populationhealth #healthoutcomes #healthcare #preventivehealthcare #personalizedhealth #personalizedhealthcare #personalizedmedicine #personalizedcare #futureofmedicine #futureofhealthcare #genomemapping #healthawareness #healthcommunication #scicomm #sciencecommunication

📽 I just added 10 recorded workshop sessions from the The National Academies of Sciences, Engineering, and Medicine's recent two day workshop on pathogen genomics in public health to the recorded trainings table available at https://lnkd.in/gd5P4E7G 🕵♀️ There are now 140 recorded webinars, trainings, and workshops available covering a wide variety of topics such as bioinformatics, genomic epidemiology, data infrastructure, public health applications of genomics, wastewater, metagenomics, and ethics. 🆘 Do you know of trainings, webinars, etc. that would be relevant to people working in genomic epidemiology or interested in the field? Please submit trainings here so I can get them added to the list: https://lnkd.in/gH5zUdvD 💡 Please share with your networks to both help direct people to available training resources as well as help me identify other resources that should be included in the tables!

Meet our experts at #ASCO2024 to learn about #RWE innovative data solutions 📊

New webinar announcement: Next up in the 2024 Data Science webinars series is a webinar on Machine Learning in modern epidemiology: Concepts, Terminology, and Their Applications in Healthcare In the webinar: Explore the potential of Machine Learning in epidemiology through this informative webinar. Learn about the fundamental concepts of Machine Learning and AI, understanding their key differences and applications. Discover how predictive modelling compares to traditional epidemiological approaches, and gain insight into the data science terminology and how this compares to epidemiological terms. The webinar will also provide a more in-depth look at clustering techniques, offering valuable knowledge on this important method for uncovering patterns in complex data. The Expert: Jip de Kok Data scientist, Department of Intensive Care at Maastricht University Medical Centre+ Jip holds a Master's in Systems Biology with a focus on Machine Learning. His experience includes research on predicting atopic conditions using microbiome data. Currently pursuing a PhD at the Intensive Care Unit in Maastricht, Jip applies Machine Learning to improve intensive care practices. Collaborating with epidemiologists and doctors, they prioritise careful data preparation and currently focus on novel clustering methods for identifying patient subgroups. This webinar offers insights from ongoing data science research in the critical healthcare setting. When: 10th of October 2024 4 -5 pm (CET) Where: Zoom (link after registration) Cost: Members from the association for epidemiologists: FREE Nonmembers €15,- Registration: secretariaat@epidemiologie.nl

Rapid, cost-effective, and scalable! The Midnight Kit is a simple, end-to-end solution for #SARSCoV2 whole-genome sequencing. Watch this Knowledge Exchange to find out about the use of nanopore sequencing for genomic epidemiology. You will learn how to prepare sequencing libraries, rapidly sequence SARS-CoV-2 genomes and how to analyse your data to identify variants of interest. Watch here: https://lnkd.in/d6wCVJsr