DIAPHONIA’s Post

#PanoramaNews - Tecniplast Scientific Director, 𝗦𝘁𝗲𝗳𝗮𝗻𝗼 𝗚𝗮𝗯𝘂𝗿𝗿𝗼 interviewed DR. 𝗟𝗲𝗼𝗻𝗮𝗿𝗱𝗼 𝗥𝗲𝘀𝘁𝗶𝘃𝗼, one of the 𝗹𝗲𝗮𝗱𝗲𝗿 in the neurobehavioral analysis and advocate for ethical and transparent 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝗳𝗶𝗰 𝗽𝗿𝗮𝗰𝘁𝗶𝗰𝗲𝘀. Restivo is the head of Neuro-Behavioral Analysis Unit (NeuroBAU) at the University of Lausanne, where the Minimal Metadata Set (MNMS) project is running. 𝗠𝗡𝗠𝗦 is an approach supporting an improved and interoperable representation of the raw data already at the source (i.e. at the level of raw data of the single animal). This aims to improve the reproducibility, accessibility and interoperability of nonclinical in-vivo data creating new more ethical and efficient 𝗮𝗻𝗶𝗺𝗮𝗹 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗺𝗲𝘁𝗵𝗼𝗱𝗼𝗹𝗼𝗴𝗶𝗲𝘀. Dr. Gaburro inquired about the MNMS and the correlations between it and other animal research principles. 𝗗𝗼𝗻'𝘁 𝗺𝗶𝘀𝘀 𝘁𝗵𝗲 𝗰𝗵𝗮𝗻𝗰𝗲 𝘁𝗼 𝗿𝗲𝗮𝗱 𝘁𝗵𝗲 𝗳𝘂𝗹𝗹 𝗮𝗿𝘁𝗶𝗰𝗹𝗲 𝗼𝗻 𝗼𝘂𝗿 #𝗣𝗮𝗻𝗼𝗿𝗮𝗺𝗮𝗡𝗲𝘄𝘀𝗹𝗲𝘁𝘁𝗲𝗿. Click here: https://buff.ly/4bz5SsF

➡️ Come & take a closer look at our partners and their work! 👀 🌊 Our colleague, @Daniela Bortotto, fish physiologist and Professor 👩🔬 at the Università degli Studi di Padova (UNIPD) explains her research 🔍 in #DIAPHONIA on physiological indicators of the effects of #underwaternoise 🔊 on #fish 🐟 and seeing if there is a link with their behaviour. Do you have any questions for her? #EUResearch #JPIOceans

Last week, a delegation of EU-LIFE attended the #EUResearchArea Conference and the 26th #ERA Forum meeting. Marta Agostinho, EU-LIFE Executive Director, advocated for a constructive policy to #AnimalResearch and the development of new approach methodologies (#NAMs) following the active role of EU-LIFE in the co-creation of the ERA action on this topic. Her main points were: • 𝗔𝘀 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗶𝗻𝘀𝘁𝗶𝘁𝘂𝘁𝗲𝘀 𝘄𝗲 𝗮𝗿𝗲 𝗳𝘂𝗹𝗹𝘆 𝗰𝗼𝗺𝗺𝗶𝘁𝗺𝗲𝗻𝘁 𝘁𝗼 𝘁𝗵𝗲 𝗱𝗲𝘃𝗲𝗹𝗼𝗽𝗺𝗲𝗻𝘁 𝗮𝗻𝗱 𝘂𝘀𝗲 𝗼𝗳 𝗡𝗔𝗠𝘀 that help to reduce the use of animals in research and regulatory testing. Likewise, we are fully committed to the Three Rs principle (Replacement, Reduction and Refinement). • Researchers are the ones developing NAMs, so 𝘁𝗵𝗲 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝗳𝗶𝗰 𝗰𝗼𝗺𝗺𝘂𝗻𝗶𝘁𝘆 𝗶𝘀 𝗮 𝗸𝗲𝘆 𝗽𝗹𝗮𝘆𝗲𝗿 for the success of any policy on NAMs and must be part of it at all stages. • The main value of this ERA action is the capacity to 𝗽𝗿𝗼𝗺𝗼𝘁𝗲 𝗰𝗼𝗼𝗿𝗱𝗶𝗻𝗮𝘁𝗶𝗼𝗻 𝗮𝗺𝗼𝗻𝗴 𝗠𝗲𝗺𝗯𝗲𝗿 𝗦𝘁𝗮𝘁𝗲𝘀, most specially at the regulatory stage; global coordination beyond the EU is also critical. • This action will only contribute to EU competitiveness if it allows the advancement of biomedical research and helps move science forward, 𝗯𝗮𝘀𝗲𝗱 𝗼𝗻 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝗳𝗶𝗰 𝗰𝗿𝗶𝘁𝗲𝗿𝗶𝗮 and not on political timelines. • The 𝘁𝗿𝗮𝗶𝗻𝗶𝗻𝗴 𝗮𝗻𝗱 𝗲𝗱𝘂𝗰𝗮𝘁𝗶𝗼𝗻 component of the action towards all actors - researchers, regulators, policy makers and citizens - is paramount. Informed policies must be based on broader understanding of the complexity of the biology behind biomedical research and on the potential risks, gains and impacts of the policies. Find out more here 🔗 https://bit.ly/3XUYnI0 #EuropeanResearch #ExcellentResearch

#TPcorporate - 𝗪𝗲 𝗵𝗮𝗱 𝘁𝗵𝗲 𝗵𝗼𝗻𝗼𝗿 𝗼𝗳 𝗶𝗻𝘁𝗲𝗿𝘃𝗶𝗲𝘄𝗶𝗻𝗴 𝗗𝗿. 𝗠𝗶𝗿𝗶𝗮𝗺 𝗗𝗶𝗮𝗺𝗲𝗻𝘁, Head of the Vivarium Department of Experimental Cancer at the 𝗜𝗻𝘀𝘁𝗶𝘁𝘂𝘁𝗼 𝗱𝗲 𝗢𝗻𝗰𝗼𝗹𝗼𝗴𝗶́𝗮 '𝗔́𝗻𝗴𝗲𝗹 𝗛. 𝗥𝗼𝗳𝗳𝗼' in Buenos Aires, Argentina. The doctor told us that: "𝗧𝗵𝗲 𝘄𝗲𝗹𝗳𝗮𝗿𝗲 𝗼𝗳 𝗹𝗮𝗯𝗼𝗿𝗮𝘁𝗼𝗿𝘆 𝗮𝗻𝗶𝗺𝗮𝗹𝘀 𝗽𝗹𝗮𝘆𝘀 𝗮 𝗰𝗿𝗶𝘁𝗶𝗰𝗮𝗹 𝗿𝗼𝗹𝗲 𝗶𝗻 𝘁𝗵𝗲 𝗽𝗿𝗼𝗱𝘂𝗰𝘁𝗶𝗼𝗻 𝗼𝗳 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗮𝗻𝗶𝗺𝗮𝗹𝘀 𝗮𝗻𝗱 𝘁𝗵𝗲 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝗳𝗶𝗰 𝗶𝗻𝘁𝗲𝗴𝗿𝗶𝘁𝘆 𝗼𝗳 𝗼𝘂𝗿 𝘄𝗼𝗿𝗸. Any alterations made to the laboratory animal environment must prioritize enhancing their physiological well-being and providing stimuli tailored to their species-specific needs. With this principle in mind, 𝘁𝗵𝗲 𝗻𝗲𝘄 𝗩𝗶𝘃𝗮𝗿𝗶𝘂𝗺 𝗲𝗻𝘀𝘂𝗿𝗲𝘀 𝘁𝗵𝗲 𝗾𝘂𝗮𝗹𝗶𝘁𝘆 𝗮𝗻𝗱 𝗿𝗲𝗽𝗿𝗼𝗱𝘂𝗰𝗶𝗯𝗶𝗹𝗶𝘁𝘆 𝗼𝗳 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗲𝗻𝗱𝗲𝗮𝘃𝗼𝗿𝘀. We have the capability to maintain 𝗱𝗶𝗴𝗶𝘁𝗶𝘇𝗲𝗱 𝗿𝗲𝗰𝗼𝗿𝗱𝘀 𝗼𝗳 𝗲𝗻𝘃𝗶𝗿𝗼𝗻𝗺𝗲𝗻𝘁𝗮𝗹 𝗰𝗼𝗻𝗱𝗶𝘁𝗶𝗼𝗻𝘀 in all animal rooms and receive real-time alerts for any deviations. We've also implemented a double-door autoclave in the washing area, as well as a dedicated clean storage area". 𝗗𝗼𝗻'𝘁 𝗺𝗶𝘀𝘀 𝘁𝗵𝗲 𝗳𝘂𝗹𝗹 𝗮𝗿𝘁𝗶𝗰𝗹𝗲. You can find it in our 𝗻𝗲𝘄𝘀𝗹𝗲𝘁𝘁𝗲𝗿 𝗽𝗮𝗻𝗼𝗿𝗮𝗺𝗮 at the following link: https://buff.ly/3vqQyOS #Tecniplast

Researchers in the DECISION-Project developed a new animal model that allows for the study of metabolic dysfunction-associated steatohepatitis #MASH progression to #cirrhosis in just 6-8 weeks, offering a faster way to test potential treatments. Read the full story from our partners at MedB LAB Universitätsklinikum Münster and Universitätsmedizin Frankfurt: https://lnkd.in/dA6rJtmE Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) Fundació Clínic per a la Recerca Biomèdica CRI - Centre de Recherche sur l'Inflammation

Two weeks before our next joint webinar with the ISTA - International Seed Testing Association. If you are interested in #SeedScience or microbes are your thing, this webinar is definitely for you! 🖥 🌱 More information (including the registration link) is at the link below.

"The #FDA policy allowing non-animal data to be used to support drug approvals needs to be much better communicated and amplified by the agency, funders and research institutions. And more researchers need to embrace the change. The outcome will be more-rigorous evaluation of experimental medications, and more-meaningful results." Check out the recent Nature editorial entitled "Animal research is not always king: researchers should explore the alternatives." https://lnkd.in/daM5czXb #EthicalResearch #NonAnimalTesting #InnovativeTechnologies #AnimalTestingAlternatives #IFER

Commentary on a Recent Study of Metformin in Non-Human Primates The SENS Research Foundation staff here continue their series of posts on the problems with studies of metformin as a potential means to modestly slow aging. Taken as a whole, the animal data for metformin is dismal, and the human data often touted ... https://lnkd.in/eTkfJ3ux #BioTech #science

I found this to be a really interesting article discussing Ophiocordyceps.

💡 During the 1️⃣ st in-person consortium meeting of the PRO-GRACE project, we took a moment to speak with project partners to get their take on why the project is important and what their specific role in it is. 💬 Ana Maria Barata, Instituto Nacional de Investigação Agrária e Veterinária, IP (INIAV, IP), talked about her organization and its activities, and shared her perspective on the importance of establishing a research infrastructure for plant genetic resources. 🎥 https://lnkd.in/erXDC8HR #PlantGeneticResources #cropbiodiversity #researchinfrastructure #research #innovation #HorizonEurope