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Did you know that specific genetic factors can increase susceptibility to conditions like depression, anxiety, schizophrenia, and bipolar disorder? Understanding these genetic risk factors is crucial for individuals and families alike. Let's illuminate the path towards a deeper understanding of genetic risk factors and pave the way for healthier futures together! #GeneticRiskFactors #MentalHealthAwareness #EmpowermentThroughKnowledge #MosaicBiodata #MentalHealthAwarenessMonth

#snsdesignthinkers #snsinstitutions #snsphysiotherapy DOWN SYNDROME A genetic chromosome 21 disorder causing developmental and intellectual delays. Down's syndrome is a genetic disorder caused when abnormal cell division results in extra genetic material from chromosome 21 (trisomy 21). SYMPTOMS: *Flattened face *Small head *Short neck *Protruding tongue *Upward slanting eye lids (palpebral fissures) *Unusually shaped or small ears *Poor muscle tone *Broad, short hands with a single crease in the palm *Relatively short fingers and small hands and feet *Excessive flexibility *Tiny white spots on the colored part (iris) of the eye called Brushfield's spots. CAUSE : *Trisomy 21 *Mosaic Down syndrome *Translocation Down syndrome RISK FACTORS: *Advancing maternal age *Being carriers of the genetic translocation for Down syndrome. *Having had one child with Down syndrome LIFE EXPECTANCY: Life spans have increased dramatically for people with Down syndrome. Today, someone with Down syndrome can expect to live more than 60 years, depending on the severity of health problems.

We all have personal experience with stress's profound effect on our bodies, but how does the epigenome respond to and regulate the stress response? Check out this enlightening review article, which highlights the intricate relationship between stress, the epigenome, and possible therapeutic interventions. Read on: https://bit.ly/3VMsiBv #Epigenetics #Stress

Addiction is a genetic disease. 🧬 Studies show differences in: 🧠 Brain waves 🍸 Sensitivity to alcohol 🧪 Effect of alcohol on hormones all pointing to → genetic differences in people who are addicted. Genetics has as much to do with addiction as it does with other chronic illnesses such as heart disease and cancer. People whose parents or close relatives are addicted were probably born with a reduced supply of and ability to use brain neurotransmitters like dopamine and serotonin - natural chemicals that help you feel good. The use of drugs/alcohol "make up" for this reduced supply of neurotransmitters. For 24/7 Addiction Help: 📞 (702) 904-8845 https://lnkd.in/gYN4DaYi #desertwindsrecovery #rehabilitation #rehabilitiationcenter #recoverycenter #aa #na #alcoholrecovery #drugrecovery #addictionrecovery #mentalhealth #sobriety #soberlife #recoverycommunity #lasvegasrehab #lasvegasrehabilitation #lasvegasrecovery

The family described in this article is a late-onset inherited metabolic disorder (IEM) with mental abnormality as the first symptom. Due to the lack of timely diagnosis, one of the two children in this family died and the other was disabled. The father of the child also had mental abnormality symptoms. The father is currently suspected of being a patient with this IEM disease. If this disease is diagnosed earlier and the two children receive correct treatment and management, this result will not occur. It is hoped that more and more families with mental illnesses will pay attention to the possibility of inherited metabolic disorders (IEM), especially the patients with mental abnormalities and eating disorders, as well as some "red flag" symptoms described below. These abnormal symptoms are likely to be manifestations of IEM diseases. These abnormal mental manifestations may be just mild manifestations of poor learning at the beginning. Many parents will mistakenly think that it is caused by the children's high learning pressure. The IEM disease in this family is Citrin protein deficiency (type II citrullinemia), which is a secondary urea cycle disorder. In type II citrullinemia, because the variants in the gene SLC25A13 either do not produce citrin protein or produce incomplete/dysfunctional citrin protein, amino acid transport cannot be carried out. This leads to metabolic dysfunction. When the patient's metabolic function is impaired, they will enter an acute phase, with recurrent hyperammonemia and accompanied by neuropsychiatric symptoms, including: nocturnal delirium, aggression, irritability, hyperactivity, delusions, disorientation, restlessness, drowsiness, memory loss, fluttering tremors, convulsive seizures and coma. Acute episodes are usually caused by alcohol and sugar intake, drugs and/or surgery. In some cases, if appropriate treatment is not taken, the patient may develop cerebral edema, which may lead to death. People with Type II Citrullinemia should limit their carbohydrate intake and the correct dietary treatment is a ketogenic diet. This diet helps minimize the accumulation of toxic substances in the blood and allows patients with Citrin Deficiency (Type II Citrullinemia) to live a normal life.

Let's discuss biomarkers for nerodegenerative and mood disorders. In Chinese.

We all know that our gut plays a role in digesting food, but did you know it might also have a say in how our brains function? The communication between the gut and the brain happens via the gut-brain axis, which has recently been thought to be a significant contributor to regulating normal brain functions and a possible risk factor for neurodegenerative disorders. #alzheimers #parkinsonsdisease #gutbrainaxis #gutbraincommunication #gutmicrobiome #microbiome #guthealth #microbiomehealth #gutmicrobiota

🍄 Are mushrooms the new superheroes for treating psychiatric disorders? 🦸♂️ Scientists are buzzing about the therapeutic potential of natural compounds over synthetic ones. > A study found that psilocybin-containing mushroom extract had more potent and prolonged effects on proteins that promote brain plasticity than chemically-synthesised psilocybin. > The naturally-derived psilocybin increased the proteins GAP43, PSD95, synaptophysin and SV2A in all four brain regions – twice as many as were impacted by the synthetic version. 💡 LGC Standards supplies a large range of chemicals for research into #MentalDisorders and #neurodegenerative diseases - including controlled substances, hallucinogens, and psychedelics. Explore now: https://okt.to/wlce9f #ResearchChemicals #ScienceForASaferWorld

Perspectives on the etiology of mental illness have evolved from demonic possession toward multisystem biologically based models that include gene expression, environmental triggers, immune mediators, and infectious diseases. Microbes are associated with a number of mental disorders, including autism, schizophrenia, bipolar disorder, depressive disorders, and anxiety disorders, as we as well as suicidality and aggressive or violent behaviors. This article reviews the association of microbes and mental illness, including autism, schizophrenia, bipolar disorder, aggression, anxiety, and depression. Many specific microbes are discussed including Babesia, Borrelia burgdorferi (Lyme disease) Candida, SARS-CoV-2), Epstein–Barr virus Influenza viruses, Mycoplasma, Group A Streptococcus (PANDAS), Recognition of the microbe and mental illness association with the development of greater interdisciplinary research, education, and treatment options may prevent and reduce mental illness morbidity, disability, and mortality. Bransfield RC, Mao C, Greenberg R. Microbes and Mental Illness: Past, Present, and Future. Healthcare. 2024; 12(1):83. https://lnkd.in/guwDSejD Thank you Nancy O'Hara, MD, MPH, FAAP for the share!

Four out of five of people with autoimmune disorders are women. New research from Stanford University has uncovered why women are much more prone to autoimmune disorders. https://lnkd.in/gn3iXCjA Scientists found that a molecule made by an X chromosome in every female cell can generate antibodies against a woman’s own tissues. Examples of these diseases are rheumatoid arthritis, multiple sclerosis, scleroderma, and fibromyalgia. These diseases have an unequal ratio between women and men. The ratio for lupus is 9 to 1; for Sjogren’s syndrome, it is 19 to 1. Psychology and writer Maytal Eyal, Ph.D. explains in length in her podcast, “Heal With It” that it seems the virtues culture rewards in women (agreeability, extreme selflessness, and suppression of anger) may predispose women to chronic illness and disease.” Self-silencing can be lethal for women of color, in particular. More than forty years ago, Harvard University psychologist Dana Jack identified that the common pattern among women with depression was a tendency to self-silence. Is it time to stop being “nice people” and self-silencing? Science seems to suggest that it is a matter of life and death.