Endeavor BioMedicines’ Post

🔬 Investigating HO-1 Regulation: Insights from BACH1 Knockout Mice in Sepsis Raghavan Pillai Raju, from the Medical College of Georgia at Augusta University, USA, shared compelling findings at Redox Medicine 2024. His research explores how HO-1 regulation is altered in BACH1 knockout mice during sepsis, providing crucial insights into the complex interplay of oxidative stress and immune responses. #HO1Regulation #SepsisResearch #RedoxMedicine

Understanding the interaction between the human host and microbiome could be game-changing in medicine. Protein-protein interactions (PPIs) play a vital role in comprehending the pathogenesis or infection in all living cells. However, the mechanisms underlying the complex interaction networks within the human gut have yet to be fully understood in CRC. Curious to learn more about this topic? Read the full article here: https://lnkd.in/gDQqWJae Feel free to share this post with your network and colleagues who might find this article valuable. #ColorectalCancer #MicrobiomeResearch #HealthcareScience #CancerResearch #CuttingEdgeScience #MedicalBreakthroughs

Our latest research uncovers the pivotal role of IL-18 in liver fibrosis. Discover how IL-18 impacts hepatic stellate cells (HSCs) and drives liver cirrhosis. This groundbreaking study sheds light on potential treatments for fibrosis. 👉 Read the full findings here: https://ow.ly/LYL150QCh1l #LiverHealth #Research #FibrosisTreatment #UCSD #UCSDHealth #UCSDACTRI

🎊 My first review publication is out in Cell Reports Medicine! 🎊 In this comprehensive review, we explore the literature on the ABC transporter family in the central nervous system, focusing on their functionality and expression changes across different cell types and diseases. Our review offers new insights that could lead to new therapeutic strategies. A big thank you to everyone who contributed to this project. Olaf van Tellingen, Mark de Gooijer, Eleonora Aronica, William Elmquist, @Wolfgang Löscher, Jann Sarkaria, @Pieter Wesseling, Oliver Langer #cellreportsmedicine Read the full publication here: https://lnkd.in/eJ3knPRp

✨Happy #FluorescenceFriday!✨ Check out this stunning image of an alveolar epithelial #organoid from the lab of Dr. Claudia Loebel, taken in our 3D Assay #Flowchip! Dr. Loebel is researching the use of engineered hydrogels in creating 3D alveolar organoids for #PrecisionMedicine. Her #research is advancing how both chronic and acute pulmonary disease are studied and treated. 💡 Learn more about her intriguing work: https://lnkd.in/g9VHTADj  🔬 Image taken with Yokogawa CV8000 

At #OpticaBiophotonics24, Golnar Mostashari (The National Institutes of Health) presented "Near Infrared Spectroscopy for Assessing Tissue Hemodynamics in Patients With Sickle Cell Disease." During the poster session, she covered the significant differences in cerebral and muscle hemodynamics between patients with sickle cell disease compared to ethnic-matched healthy controls. #Biophotonics #Medicine #MedicalTechnology

Heart failure with preserved ejection fraction (HFpEF) is increasingly prevalent, often associated with cardiac amyloidosis 🫀 In their latest article, Elena Cavallone et al. review the crucial role of oxidative damage in the progression of this condition. The study highlights how reactive oxygen and nitrogen species lead to cardiomyocyte damage, hypertrophy, and fibrosis, perpetuating a cycle of inflammation and redox damage. Understanding these mechanisms opens doors to potential therapeutic strategies. Dive into the detailed analysis and future prospects in cardiac amyloidosis research: https://lnkd.in/eNwSiYb4 Università degli Studi di Torino #HeartFailure #MedicalResearch #OxidativeStress

In this single-center prospective case-control study, the findings illuminate the association between thromboembolism, pyoderma gangrenosum, and subsequent wound healing outcomes. https://ja.ma/3W6sdsD

In this single-center prospective case-control study, the findings illuminate the association between thromboembolism, pyoderma gangrenosum, and subsequent wound healing outcomes. https://ja.ma/3HXIesL

🌬️ Breaking News in Medicine: A Breath of Fresh Air for Lung Health! 🔬 Researchers from the Center for Regenerative Medicine (CReM), a joint venture between Boston University and Boston Medical Center, have discovered a novel approach for engrafting engineered cells into injured lung tissue. These findings may lead to new ways for treating lung diseases, such as emphysema, pulmonary fibrosis and COVID-19. . 🌟🌬️Your lungs are your lifeline. Let's celebrate this incredible step forward in the journey to breathe easier and live healthier lives! 💨💚 #LungHealth #MedicalBreakthrough #RegenerativeMedicine #RespiratoryHealth #athenaeumpub #JournalofRegenerativeMedicineandBiologyResearch