John Baust, President and Lead Scientists at CPSI Biotech, answers questions at the last CryoChats™ entitled 'Cryopreservation Benefits and Costs of DMSO' on April 17th, 2024. Question: "For post thaw assays, it is just enough to check for flow data and compare with pre thaw numbers or is it ok to expand these cells for few days, check for viability and also carry out flow data to be sure your cryo formulation had no impact on the cells." John also provided this link as a reference: https://lnkd.in/eZN6qBUY Join us for our next CryoChats™ entitled "Cryopreservation Clinical Risks" on June 12, 2024 at 1PM CDT. Register Here: https://lnkd.in/gUXVHa83 6/12 Assessing Operational Risk and Clinical Impact 7/31 Cryopreservation Scaling
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Our colleagues will be presenting at the upcoming FBLD Conference 2024 between the 22nd-25th September in Boston. https://lnkd.in/gnvHkNyw If you are attending the conference, check out the exciting oral presentations below. Astex Presentations: 1. David Rees (Opening Keynote) - 25 Years of Thinking Small 2. Puja Pathuri - Fragment-Based Discovery of Allosteric Modulators of β-Glucocerebrosidase 3. Paul Mortenson - Marrying Structures with Computation for Augmented Fragment-Based Drug Discovery 4. Andrew Woodhead - Biological Validation of a Novel eIF4E Binding Site Identified by Fragment Screening Using Mutational Analysis and Targeted Protein Degradation #Fragments #DrugDiscovery
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#DiagnosticEfficiency👩🏼🔬 A significant breakthrough in the development of Gentian Diagnostics' turbidimetric #NTproBNP assay, now entering the verification phase. Gentian aims to make NT-proBNP analysis more accessible on high throughput, open channel instruments improving both cost and workflow efficiency. The Gentian assay will uniquely target non-glycosylated areas of the molecule, and therefore measure the total amount of NT-proBNP, unlike most current commercial tests which bind to glycosylated regions of NT-proBNP molecule. Gentian will present the poster: "Development and diagnostic utility of immunoturbidimetric NT-proBNP assay based on antibodies targeting glycosylation-free regions of NT-proBNP at #ADLM2024 in Chicago in July. The poster describes a comparison of the Gentian assay with another commercially available assay. The results confirm the underestimation of NT-proBNP concentration in clinical samples due to glycosylation effects, which Gentians’ prototype successfully avoids. 👉 Learn more: https://lnkd.in/dc_6BSEY #Heartfailure #clinicalchemistry #diagnostics
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🗓️ Meet Us at DOT Septebmer 30th - October 3rd! We're excited to be attending Discovery On Target next month. Come see us at Booth #117 to discuss how we can partner with you to accelerate your research with cutting-edge technologies. We are expanding our service offerings to accelerate your drug discovery programs: 🚀 New Crystallographic Fragment Screening Technologies: Our crystallographic fragment screening platform allows for immediate structural visualization and binding confirmation of your bound fragments to give you the crucial information to drastically kick-start your SBDD program. 🚀 High Throughput Screening with SPR: Proteros offers screening of 186k centroid-based library screening by SPR, the gold standard biophysical methods. Proteros developed a proprietary screening strategy by SPR to maximize efficiency and directly identify binders to your target in 6 weeks. If feasible, binders can be quickly followed up with a functional assay and validated by co-crystallization or cryo-EM structure to develop a uniquely qualified hit to rapidly advance your early-stage program. 🚀 19-F NMR Screening: If your target is not able to be crystalized, you can now utilize our 19F-NMR based screens with a fluorinated fragment library. 💡Ready to learn more? Reach out to us today to see how we can be your trusted partner in drug discovery! #DrugDiscovery #Biotechnology #Proteros #DOT2024 #ReachRightFaster
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Find, analyze and isolate your most valuable cells, with ease and speed with our supercharged Cyto-Mine® coming soon!🎆🚀 What can you expect from the new supercharged Cyto-Mine®? ✔️Screen tens of millions of cells per day ✔️Rapidly identify and isolate rare cells of interest ✔️Ensure monoclonality of selected cells ✔️Ability to multiplex assays ✔️Save time and budget ✔️Complete projects faster 🤔Curious to find out more? Take a peek here: https://bit.ly/3LTSnIK #CellLineDevelopment #AntibodyDiscovery #DrugDiscovery #SingleCell #SphereFluidics
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In a recent investor webinar, our Executive Director, Thomas Duthy provided an in-depth breakdown of our recent Phase I/II Clinical Trial Results for Rett Syndrome. Watch the update below as he explains the findings. You can watch the full investor webinar here: https://lnkd.in/gWntFZps #RettSyndrome #Retts #Biotech #NTI #Neurotech
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Co-precipitation of metal carbonate templated protein microparticles - using the KNAUER IJM NanoScaler Without a doubt, the KNAUER IJM NanoScaler and IJM NanoProducer are the industry standard for developing lipid nanoparticles utilized in mRNA-based vaccines. Together with Charite, Germany's largest research hospital, we have successfully developed protein metal carbonate hybrid particles by mixing MnCl2 and Na2CO3 salt solutions. Our team in Berlin is driven by the desire to provide scientists with the tools they need to develop the next breakthrough in medicine. „Thank you, Svea Stephan and Nadia, for your hard work.“ think LNP. think KNAUER KNAUER #mRNA #LNP #KNAUER
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💡 Did you know that the majority of #GPCR structures have been solved with cryo-EM? 🔬 GPCRs have an inherent complexity and often destabilize outside of their native cell membrane environment, making them difficult to study with traditional methods. #cryoEM overcomes these challenges. 👩🔬 Join Dr. Emily Armbruster, CCO Kristin Rider, and Hannagh Smith at Hanson Wade Group's GPCRs-Targeted Drug Discovery Summit next week, March 6-7 in Boston to learn how you can get a structure in under 4 weeks. 📖 Learn more about high resolution data collection for GPCRs: https://lnkd.in/gvwEgvET
GPCRs
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The first assay that makes use of the Dual Reporter functionality is out! Join us for the webinar to learn more about this assay and how you can even further multiplex your research!
See how you can double your multiplex data with ProcartaPlex signaling dual reporter assays from our partner, ThermoFisher Scientific! Join the free webinar to learn about the xMAP INTELLIFLEX DR-SE System and benefits of dual reporter capabilities from Senior Director of Scientific Affairs at Luminex, Dr. Sherry Dunbar and Dr. Sigrun Badrnya, Manager of Research and Development in Protein Cell Analysis at Thermo Fisher Scientific. Sign up now to attend on March 20th at 8:00 a.m. PDT/4:00 p.m. CET! https://hubs.li/Q02pBLk90
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Check out our upcoming webinar!
See how you can double your multiplex data with ProcartaPlex signaling dual reporter assays from our partner, ThermoFisher Scientific! Join the free webinar to learn about the xMAP INTELLIFLEX DR-SE System and benefits of dual reporter capabilities from Senior Director of Scientific Affairs at Luminex, Dr. Sherry Dunbar and Dr. Sigrun Badrnya, Manager of Research and Development in Protein Cell Analysis at Thermo Fisher Scientific. Sign up now to attend on March 20th at 8:00 a.m. PDT/4:00 p.m. CET! https://hubs.li/Q02pBLk90
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Join us at this free webinar to learn about the xMAP INTELLIFLEX System and the first commercially available dual reporter assay!
See how you can double your multiplex data with ProcartaPlex signaling dual reporter assays from our partner, ThermoFisher Scientific! Join the free webinar to learn about the xMAP INTELLIFLEX DR-SE System and benefits of dual reporter capabilities from Senior Director of Scientific Affairs at Luminex, Dr. Sherry Dunbar and Dr. Sigrun Badrnya, Manager of Research and Development in Protein Cell Analysis at Thermo Fisher Scientific. Sign up now to attend on March 20th at 8:00 a.m. PDT/4:00 p.m. CET! https://hubs.li/Q02pBLk90
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