I am pleased to share with you my recent publication in Angewandte Chemie - "Rhodium-Catalyzed Asymmetric Macrocyclization towards Crown Ethers Using Hydroamination of Bis(allenes)". Chiral crown ethers (CEs) exhibit strong asymmetric induction in phase transfer catalysis, supramolecular catalysis and molecular recognition processes. In this study, a practical catalytic asymmetric macrocyclization method is described for the gram-scale synthesis of a class of chiral CEs using Rh-catalyzed hydroamination of bis(allenes) with diamines. Using this approach, a wide range of chiral CEs with ring sizes ranging from 12 to 36 were successfully prepared with high enantioselectivity. This project was accomplished in the Breit Group. I appreciate the nice discussions we had during this project. https://lnkd.in/evF5jdcJ
Congratulations 🎉
Congratulations Farhad. Great job
great job
Wow, pretty good work Farhad Panahi
Congratulations, dear Dr. Panahi and nice to hear from you again. 🌹🌹
Well deserved 🤞
Congratulations Dr. Panahi 👏
Good luck dear Dr. Panahi.
Well done! Congrats Dr.Panahi. 👌
Congratulations