HDT Bio’s Post

T cells play a pivotal role in immune defense and cancer surveillance. A golden standard for enumeration of activated T cells is ELISpot. By defining the right assay parameters, ELISpot read-outs are highly informative. This golden standard method is cost-effective and ideal to support clinical studies. In our recent publication, Julian Freen-van Heeren, PhD; @Irma Rensink Annelies Turksma; Anja ten Brinke of our R&D team, share our insights for setting up an IFN-γ ELISpot that allows precise enumeration of antigen-specific T cells. As model system we assessed SARS-CoV-2-specific T cell responses and compared pre-pandemic and post-recovery T cell responses. At Immunomonitoring services, we are well-equipped for evaluating antigen specific T cell responses by ELISpot as well as other methods to identify the effects on T cell biology. For more information: Assessing Antigen-Specific T Cell Responses Through IFN-γ Enzyme-Linked Immune Absorbent Spot (ELISpot) - PubMed (nih.gov) https://lnkd.in/g7-D3Bhc #ELISpot #vaccine #immuneoncology #Bioanalysis #BiotechServices #PharmaServices Annick de Vries, Floris Loeff, Karien Bloem

Explore the journey of mRNA vaccines and their revolutionary potential beyond COVID-19 in our latest blog. Discover how mRNA could transform healthcare, from fighting cancer to tackling global diseases. https://lnkd.in/eADub7rP

Attending #AbuDhabiGlobalHealthcareWeek. Fascinating views from top global experts about interactions of AI and biotech including mRNA and the future of precision medicine. Post #COVID19 lessons learned and how to predict and address the next pandemic are still at the core of public policy considerations. #Ziphius is developing next generation self-amplifying #mRNA vaccines and therapies which are targeting those future challenges in infectious diseases, cancer and protein replacement. Www.ziphius.org

Come and visit us at AAI2024 and learn about the power of Seromics

Check out this recently released short documentary showcasing the fantastic work Infinitopes is doing to develop high-efficiency #cancer #vaccines that are affordable for both healthcare systems and patients. See for yourself the transformative impact that BioEscalator companies are making in the field of #healthcare. At the BioEscalator, we proudly support visionary companies like Infinitopes in their pursuit of achieving their goals. #InnovationInHealthcare #Collaboration #SuccessStory

We're in Chicago for #AAI2024! Be sure to visit us at Booth 532 to learn how the #HuProt™ microarray helps identify disease biomarkers, inform potential treatments, and predict immune-related adverse events. While you're there, don't miss our Theater Workshop on Sunday, May 5 @ 9:30am (Level 3, Hall F1 - Workshop 2) where our CSO, Tyler Hulett, PhD, will be presenting valuable insights into, "Seromics: A New Frontier of Immune Biomarkers and Druggable Target Discovery." https://lnkd.in/grV2raFE #immunology #biomarkers #autoimmunedisease #seromics #proteomics #antibodies #autoantibodies

It may seem strange to those in the Northern hemisphere, but here in Melbourne, Australia, autumn is upon us. The end of April is also a time to remember International Day of Immunology (29th April) - https://lnkd.in/gf_khWHA. Anyone who has ever had a vaccine, or lived or cared for someone with an auto-immune condition, or received immune-therapy for cancer may know that the immune system can sometimes be your best friend, or it can feel like your worst enemy. If you want to learn more about the companies, hospitals, research institutes and universities learning to better harness and control our immune systems, register for the Asia-Pacific Vaccine & Immunotherapy Congress, 14-17 May 2024, Marvel Stadium, Melbourne (www.apvic.org). Today is the last day for Late-Breaking Abstracts ($200 for students, $600 for others)

#ACROHighlights [Featured Product] 🎯CA IX, a transmembrane protein found in hypoxic tumors, plays a vital role in pH balance and tumor survival. It's also a promising therapeutic target. As a valuable biomarker, CA IX is associated with poor prognosis, metastasis, and treatment resistance, providing crucial insights into tumor behavior. Unlock the potential of CA IX with our top-quality proteins! Perfect for immunization, antibody screening, CAR expression detection, and more. 🧪 Explore our CA IX protein range now: https://smpl.is/868g1 #CancerResearch #TumorBiomarkers #TherapeuticTarget #ACRObiosystems

More #AACR posters released! TIL analysis demonstrates different mechanisms underlying PD-1 resistance in animal models:https://lnkd.in/eVd2pgwS Identification of fully human CCR8 antibodies that demonstrate excellent ADCC function, potent blocking activity, and robust anti-tumor immune responses: https://lnkd.in/eRCW9pYC A first-in-class bispecific ADC targeting FOLR1 and MUC1 exhibits promising anti-tumor activity in a FOLR1low xenograft model: https://lnkd.in/eYhwqTrG #AACR2024 #AACRConference #AACRMeeting #CancerAwareness #TumorResearch #immunodeficient #preclinicalresearch #immunotherapy #cancerresearch #cancertherapy #PreclinicalStudies #HumanizedModels #renbiologics #antibodylibrary

We have just celebrated an International Day of Immunology under the theme: Immunity Through the Ages: Navigating the Science of Aging and Immunology. Here at Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO)- University of Geneva multiple groups work on various topics from vaccines to understanding diseases and fight against infection, autoimmunity, and cancer. #ImmunologyDay #ImmunityThroughTheAges #CelebrateImmuneSystem