Healthcare 360 Magazine’s Post

#Alzheimer’s disease (#AD) Inhibition of #PSD95 corrects these Aβ-induced synaptic defects and reduces seizure activity in APP/PS1 ➡️ #mice ⬅️. Our results demonstrate a mechanism underlying elevated seizure activity during early-stage Aβ #pathology and suggest that PSD-95 could be an early #biomarker and novel #therapeutic target for AD.

Genetic testing for hereditary heart conditions can help speed diagnosis and treatment, especially in patients with overlapping clinical findings. Learn more about how Invitae’s cardiology tests can be an essential tool for comprehensive care: https://invit.ae/4bily2t

This is a fabulous review detailing the strategies for modulating programmed cell death mechanisms in the context of disease. Thanks to Joshua Webster from #GenentechResearchPathology for his contributions and to his co-authors Nobuhiko Kayagaki and Kim Newton from #GenentechPhysiologicalChemistry. #genentech #pathology

New study - in a study led by Boston University, we found that circulating levels of cells which repair blood vessels were associated with Alzheimer's disease risk, with higher number of these regenerative cells associated with lower risk. This association persisted even when correcting for age, biological sex, and APOE4 status (one of largest genetic risk factors for AD). This has implications for promoting vascular health in those at risk of AD- and we know from other studies that diet and exercise significantly alter your circulating regenerative cells- so possibly a mechanism by which physical activity may reduce AD risk https://lnkd.in/eXP-gxXz

Hereditary #neuromuscular diseases are multifactorial conditions that are difficult to ascertain, considering that 60% of patients do not have an accurate diagnosis. In Europe, 500,000 people suffer from these diseases, and 30% of cases result in permanent disability. The European project CoMPaSS-NMD proposes an innovative approach to the diagnosis of these diseases based on #ArtificialIntelligence. "The goal is to develop AI algorithms to improve the diagnosis of hereditary neuromuscular diseases" explains Annalisa De Angelis, Dissemination and Communication Consultant at Deep Blue, a project partner. "Being caused by various and complex genetic interactions, these conditions are very difficult to understand, even for a specialist". "For this reason, it is necessary to find a way to effectively use patient data to quickly understand what is happening and intervene promptly with an appropriate therapeutic plan" emphasizes the geneticist Rossella Tupler, project coordinator. "CoMPaSS-NMD aims to develop a patient classification system that leverages Artificial Intelligence to support doctors, helping them to process very complex data and to quickly understand the diagnostic and therapeutic direction to take." READ THE FULL ARTICLE 👇

Breast cancer occurs when abnormal breast cells grow uncontrollably, forming tumors. It’s the most common cancer in women worldwide, making up 25% of all cases. Risk factors include age, family history, genetics, hormone replacement therapy, and lifestyle factors like alcohol consumption and obesity. Early detection is the key- check for symptoms and consult your physician if needed. 💖🎗 #breastcancerawareness #breastcancerawarenessmonth #fightbreastcancer #breastcancer #stayhealthy #mendine

Knowledge is power! 🩸💡 Understanding the risk factors for blood clots is crucial. Are you aware that conditions like atherosclerosis, atrial fibrillation, cancer, genetic disorders, certain surgeries, diabetes, and family history can increase the risk? Stay informed, stay healthy. Visit us: https://lnkd.in/dAFbBd9f Call Now:- +1 805-876-3273 #patientselftesting #hospital #onthegohealth #PTINRManagement #WarfarinWonder #MedicalHistory #MedicalTrivia #FunFacts #HiddenHistory #BloodClotAwareness #StayVigilant #HealthFirst #thrombosis #venousthrombosis #healthpartner #staypositive #BloodClotting #TravelINRTips #BloodClotAwareness #HealthIsWealth #KnowYourRisk

Older adults are at high risk for seizures with Alzheimer's disease diagnosis. These individuals also have higher mortality rates than unaffected individuals. Our newest work demonstrates that seizures directly worsen the long-term consequences of Alzheimer's-related genetic risk factors, including accelerating mortality. Treating #seizures in #alzheimers should be a #therapeutic priority.

A family history of heart disease can be a significant risk factor for developing the condition. If one or more of your parents or siblings have had heart disease, you may be at increased risk due to inherited genetic factors that contribute to high blood pressure, high cholesterol, or other cardiovascular risk factors. This is because certain genetic mutations can affect the way your body processes lipids, blood clotting, and blood pressure, increasing your likelihood of developing heart disease. Talking to your doctor about your family history can help you better understand your individual risk factors and develop a personalized plan to reduce your risk of heart disease. #hearthealth #heart #heartdisease #cardiology #hearthealthy #cardiologist #healthyheart #heartattack #cardio #cardiovascular #doctor #heartdiseaseawareness #cardiovasculardisease #cardiacsurgery #heartbeat #heartsurgery #cardiac #hearthealthawareness #heartfailure #cardiacarrest #ecg #eeg

Endometriosis is known for its complex manifestations and elusive phenotypes. Pathophysiological explanation with current theories fails to encompass all scenarios, which urges for further exploration of genetic and autoimmune factors. The spectrum of endometriosis presentation, ranging from superficial appearance to significant fibrosis and scarring, makes diagnosis and treatment complex. Therefore, it is important to tailor treatment by considering each patient's distinct symptoms, employing advanced imaging techniques, and providing an ongoing care approach that includes the monitoring of co-existing conditions like IBS and interstitial cystitis. Read more here: https://ow.ly/1Pcq50Qt3TG #Endometriosis #OBGYN #WomensHealth #PelvicPain