HFUX Research | Medical Human Factors’ Post

‼️📢‼️FDA MEDWATCH - FDA SAFETY COMMUNICATION on BioZorb Markers and Potential Risks with Use in Breast Tissue‼️📢‼️ The FDA issued a safety communication to inform patients and health care providers about the potential risk of serious complications with the use of Hologic BioZorb Marker and BioZorb LP Marker devices in breast tissue. To read more and find out about what the safety communication provides, follow the link below. #fda #safety #breastimaging #biomarkers #softtissue #radiography #hologic #cosmeticsindustry #cosmeticscience #radiation #radiationtherapy #radiationoncology #breastcancerawareness #breastcancer #breastcancercare #healthcareindustry #risks #serious #complications #medicaldeviceregulation

📃Scientific paper: Teprotumumab in advanced reactivated thyroid eye disease Abstract: PURPOSE: To report the case of a patient with reactivated, refractory thyroid eye disease (TED) treated with teprotumumab. OBSERVATIONS: A 51-year-old female with a 16-year history of thyroid eye disease previously treated with orbital decompression and multiple eyelid surgeries presented in a recurrent flare of the disease. The disease recurrence was refractory to intravenous steroid therapy and only partially responsive to oral steroid therapy, and the patient developed dysthyroid optic neuropathy in the right eye with decreased visual acuity and color vision. Clinical activity score was 8/10 and proptosis measurements were 27 mm OD and 26 mm OS. The patient underwent treatment with eight infusions of teprotumumab coinciding with a low taper of oral prednisone and experienced resolution of dysthyroid optic neuropathy, decrease of clinical activity score to 1, and dramatic improvement in proptosis (17 mm OD, 17 mm OS) and extraocular muscle size on imaging. Thirty weeks after completion of teprotumumab and 2 weeks after the second dose of the COVID vaccine, she experienced another flare and subsequently underwent bilateral orbital decompressions. CONCLUSION: This case report suggests teprotumumab may be used in patients with reactivation of longstanding thyroid eye disease. Reduction of extraocular muscle size and improvement in proptosis suggest teprotumumab may be disease-modifying even in advanced cases. Continued on ES/IODE ➡️ https://etcse.fr/kf7i ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you.

Statins, metformin, and aspirin have been reported to reduce the incidence of hepatocellular carcinoma (HCC). However, the effect of their perioperative use on survival outcomes of HCC patients following curative liver resection still remains unclear. In our study, 353 patients with a first diagnosis of HCC who underwent curative liver resection were included. Propensity score matching analysis with a users: nonusers ratio of 1:2 were performed for each of the medications (statins, metformin, and aspirin). Overall survival (OS) and recurrence-free survival (RFS) were evaluated and multivariable Cox proportional hazard analysis was performed. In our study, 62 patients received statins, 48 patients used metformin, and 53 patients received aspirin for ≥90 days before surgery. None of the medications improved OS. RFS of statin users was significantly longer than that of nonusers (p = 0.021) in the matched cohort. Users of hydrophilic statins, but not lipophilic ones had a significantly longer RFS than nonusers. Multivariable analysis showed that statin use significantly improved RFS (hazard ratio [HR]: 0.41, 95% confidence interval [CI]: 0.17–0.97, p = 0.044). No difference was seen in RFS between metformin users and nonusers. Among patients with diabetes, RFS was nonsignificantly longer in metformin users than in non-metformin users (84.1% vs. 60.85%, p = 0.069) in the matched cohort. No difference in postoperative RFS was seen between aspirin users and nonusers. Therefore, we concluded that preoperative use of statins in patients with HCC can increase RFS after curative liver resection, but metformin and aspirin were not associated with improved survival. Randomized controlled trials are needed to confirm the findings of the present study. The results of our study are now available in the Cancer medicine journal at the following link: https://lnkd.in/ep7nQQ9p #HCC #Surgery #Hepatology #Statin #Aspirin #Metformin #Hepatectomy #Liverresection #Liver_resection #survival #recurrence #liver

📃Scientific paper: Teprotumumab in advanced reactivated thyroid eye disease Abstract: PURPOSE: To report the case of a patient with reactivated, refractory thyroid eye disease (TED) treated with teprotumumab. OBSERVATIONS: A 51-year-old female with a 16-year history of thyroid eye disease previously treated with orbital decompression and multiple eyelid surgeries presented in a recurrent flare of the disease. The disease recurrence was refractory to intravenous steroid therapy and only partially responsive to oral steroid therapy, and the patient developed dysthyroid optic neuropathy in the right eye with decreased visual acuity and color vision. Clinical activity score was 8/10 and proptosis measurements were 27 mm OD and 26 mm OS. The patient underwent treatment with eight infusions of teprotumumab coinciding with a low taper of oral prednisone and experienced resolution of dysthyroid optic neuropathy, decrease of clinical activity score to 1, and dramatic improvement in proptosis (17 mm OD, 17 mm OS) and extraocular muscle size on imaging. Thirty weeks after completion of teprotumumab and 2 weeks after the second dose of the COVID vaccine, she experienced another flare and subsequently underwent bilateral orbital decompressions. CONCLUSION: This case report suggests teprotumumab may be used in patients with reactivation of longstanding thyroid eye disease. Reduction of extraocular muscle size and improvement in proptosis suggest teprotumumab may be disease-modifying even in advanced cases. Continued on ES/IODE ➡️ https://etcse.fr/kf7i ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you.

🔍 Optimizing Pre-Surgery Decolonization Protocols: A Crucial Step for Patient Safety ✅ Pre-surgery decolonization protocols aim to reduce the microbial burden on patients, minimizing the risk of surgical site infections (SSIs) and other post-operative complications. MRSA decolonization stands as a cornerstone in this endeavor. ✅ Recognizing patients at heightened risk of MRSA colonization is key. Factors such as chronic kidney disease, diabetic renal impairment, congestive heart failure, advanced age, and exposure to high contrast media volumes warrant special attention. ✅ The protocol integrates targeted interventions to combat MRSA colonization effectively. This may include nasal application of Povidone-Iodine solution, chlorhexidine bathing, and rigorous environmental disinfection measures. ✅ By preemptively addressing MRSA colonization, we not only reduce the likelihood of MRSA-related SSIs but also enhance overall surgical outcomes. This proactive approach aligns with our commitment to patient safety and quality care delivery. ✅ Guided by evidence-based guidelines, our protocol ensures adherence to industry standards, fostering consistency and efficacy in pre-surgery decolonization efforts. _____________________________________________________________________ P.S. Something I'm honored to work on with Shaukat Khanum Memorial Cancer Hospital and Research Centre (Infographic) ✨ Ready to optimize your medical content? Elevate your pre-operative infection care with our expert medical and pharmaceutical writing services. DM "MPW" to learn more about my services. #MRSA #InfectionPrevention #HealthcareSafety 🩺

Blood Components in Blood banking and Blood transfusions Red Blood Cells (RBCs) - Function: Carry oxygen to tissues - Storage: 35-42 days at 2-6°C - Indications: Anemia, blood loss, surgery Plasma - Function: Transport proteins, clotting factors, and antibodies - Storage: Frozen (-18°C) for up to 1 year - Indications: Bleeding disorders, liver disease, shock Platelets - Function: Blood clotting - Storage: 5-7 days at 20-24°C with agitation - Indications: Low platelet count, bleeding disorders ✔ Cryoprecipitate - Function: Clotting factors (FVIII, FXIII, vWF) - Storage: Frozen (-18°C) for up to 1 year - Indications: Hemophilia A, von Willebrand disease ✔ Fresh Frozen Plasma (FFP) - Function: Clotting factors, antibodies - Storage: Frozen (-18°C) for up to 1 year - Indications: Bleeding disorders, liver disease Granulocytes - Function: Fight infection - Storage: 24 hours at 20-24°C - Indications: Severe infections, neutropenia Albumin - Function: Maintain blood volume, transport proteins - Storage: 2-30°C for up to 3 years - Indications: Shock, burns, liver disease ◆ Component Preparation - Whole blood is collected from donors and processed into components - Centrifugation separates blood into layers: plasma, buffy coat (platelets & WBCs), and RBCs - Components are then extracted, tested, and stored for transfusion ◆ Component Transfusion RBCs: Anemia, blood loss, surgery - Plasma: Bleeding disorders, liver disease, shock - Platelets: Low platelet count, bleeding disorders - Cryoprecipitate: Hemophilia A, von Willebrand disease - FFP: Bleeding disorders, liver disease - Granulocytes: Severe infections, neutropenia ✔ Blood Banking Benefits - Component therapy allows for targeted treatment - Reduced risk of transfusion-related complications - Improved patient outcomes - Efficient use of donated blood In conclusion, blood components are essential for treating various medical conditions. Understanding their functions, storage requirements, and indications is crucial for availabiity safe and effective transfusion practice. #MedicalLaboratoryTechnology #Microbiology #Phlebotomy #LaboratoryTesting #DiagnosticTesting #HealthcareProfessional #MedicalTesting #ClinicalLaboratory #BiomedicalScience #HealthcareIndustry #MedicalScience #LaboratoryMedicine #ClinicalMicrobiology #InfectionControl #PhlebotomyTechnician #MedicalLabTechnician #MicrobiologyLab #ClinicalLab #HealthcareCareer #MedicalCareer #ScienceCareer #COVID19Testing #Virology #Bacteriology #Parasitology #MolecularDiagnosis #GeneticTesting #Cytology #Histopathology #Immunology #Serology

#ophthalmology #uveitis #retina #acute_retinal_necrosis #ARN #herpesviruses #infection #inflammation #retinaldetachment #diagnosis #treatment #vision #review #update ✅ Check out our latest 📰 on Acute Retinal Necrosis (ARN) 👁 📖 ARN is a rare but severe ophthalmic pathology defined by panuveitis, retinal necrosis, and high rates of retinal detachment. It may lead to poor visual outcomes even if promptly diagnosed and treated. Despite significant progress in diagnosing and treating ARN, further research is needed to improve visual outcomes in this challenging clinical condition.

Redefining Rural Healthcare: Penn Trafford Family Medicine Pioneer Leads in Skin Cancer Detection with DermaSensor!   Kevin Wong, MD stated, “This is a rare quadruple win in medicine! It’s a win for the patients, a win for the providers, a win for dermatologists, and a win for insurers. For the patients, it may provide peace of mind with an adjunctive medical device for detecting all three common skin cancers. For the providers, DermaSensor generates an immediate, objective assessment of suspicious skin lesions for timely referrals. For dermatologists, DermaSensor helps prioritize patients requiring a higher level of care and more immediate attention. And for the insurers, this can result in prompt evaluation and treatment if malignancy is detected.” Read more https://lnkd.in/dBRdcYQi

Approximately 6.1 million upper endoscopies are performed annually in the U.S. (Peery et al., 2019). This diagnostic procedure is crucial for identifying conditions like gastroesophageal reflux disease (GERD), ulcers, cancer, precancerous abnormalities, and celiac disease. Upper endoscopies are recommended in various scenarios, such as investigating persistent heartburn, gastrointestinal bleeding (indicated by dark stools), nausea, vomiting, stomach pain, difficulty swallowing, pain during swallowing, and unexplained weight loss. Patients with cirrhosis may undergo regular upper endoscopies due to the risk of life-threatening esophageal vein enlargement. Analyzing endoscopic studies is pivotal for guiding interventions. TIMS MVP software enables GI specialists to record, analyze, document, and archive endoscopic findings into PACS/VNA. This comprehensive archiving enhances accessibility to patient data and facilitates informed decision-making. We are dedicated to streamlining workflows and improving patient outcomes. Join us in integrating TIMS MVP into your clinical practice! To learn more, contact us for a complimentary demonstration: https://lnkd.in/gkTSiKmR References Peery, A. F., Crockett, S. D., Murphy, C. C., Lund, J. L., Dellon, E. S., Williams, J. L., Jensen, E. T., Shaheen, N. J., Barritt, A. S., Lieber, S. R., Kochar, B., Barnes, E. L., Fan, Y. C., Pate, V., Galanko, J., Baron, T. H., & Sandler, R. S. (2019). Burden and Cost of Gastrointestinal, Liver, and Pancreatic Diseases in the United States: Update 2018. Gastroenterology, 156(1), 254–272.e11. https://lnkd.in/gvwfCPsZ

It's time to Crack the IR Code! 🕵️♂️ Today's Case: CT Guided Core Biopsy Retroperitoneal Lymph Node CLINICAL INDICATION: History breast cancer and bladder cancer; positive smoking history; retroperitoneal lymphadenopathy; oncology requests CT‐guided biopsy for evaluation of potential metastatic disease. MEDICATIONS: 2 mg Versed IV; 100 mcg fentanyl IV. Sedation time: 30 minutes. FINDINGS: The risks and benefits of CT‐guided retroperitoneal lymph node biopsy were discussed with the patient and her family members prior to the exam. Questions were answered and informed written consent was obtained. The patient was placed prone on the CT table. ***The retroperitoneal lymphadenopathy along the left aspect of the aorta was located below level of the left renal vein.*** The back was prepped and draped in standard sterile fashion. The subcutaneous tissue and retroperitoneal tissue anesthetized with 1 % Lidocaine. With CT guidance a 17‐gauge Cook biopsy needle was advanced to the posterior margin of the retroperitoneal lymphadenopathy. Four 18‐gauge core biopsy samples were obtained with a 10 mm biopsy. The patient tolerated the procedure well. Post procedure scanning appeared negative for retroperitoneal hematoma. The patient’s vitals were stable throughout the exam. The patient was discharged to the recovery unit for 3 hour bed rest and observation. During the exam the patient was sedated with intravenous Versed and fentanyl. The patients vitals were monitored prior during and after the exam by a radiology sedation nurse. Procedure and sedation time was 30 minutes. IMPRESSION: Four 18‐gauge core biopsy samples obtained from left retroperitoneal lymphadenopathy with CT guidance. No evidence of immediate post procedure complication. CPT Codes: ✅49180 Retroperitoneal Lymph Node Biopsy ✅77012 CT Guidance ✅99152 Moderate sedation first 15 minutes ✅99153 Moderate sedation each additional 15 minutes Comments -- ➡️ Code 49180 is assigned for biopsy of retroperitoneal lymph nodes. Code 38505 is assigned for biopsy of superficial lymph nodes. The retroperitoneal lymph node is a deep biopsy and is assigned code 49180. ➡️ Code 77012 is assigned for CT guidance. In accordance with NCCI rules, this code may only be assigned one time per session. ➡️ 30 minutes of moderate conscious sedation noted, billed in 15 minute increments. (99152, 99153) Never miss a post! If you're on LinkedIn, go to my profile page, click on the bell in the top right corner to receive notifications. #radrx #crackingtheIRcode #circc #interventionalradiologycoding #ivrcoding #ircoding