Arash Mostaghimi, MD, MPA, MPH and colleagues provide an updated systematic review and meta-analysis of medical comorbidities associated with alopecia areata and identified 57 comorbidities with positive odds ratios and 6 comorbidities with negative odds ratios. In the American Journal of Clinical Dermatology - see link below. #alopeciaareata #comorbidities #metaanalysis
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This systematic review by Marina Beraza Millor and colleagues analyzes the application of genetic substrate reduction therapy for the treatment of lysosomal storage diseases. #lysosomalstoragediseases #genetherapy #FabryDisease #openaccess https://lnkd.in/gJKmy_bs
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This PK simulation-based analysis by Ashish Srinivasan and colleagues highlights the potential of using post-intensification infliximab trough thresholds associated with aspirational treatment targets in Crohn’s disease and ulcerative colitis to guide choice of infliximab dose intensification strategy. #inflammatoryboweldisease #infliximab #doseintensification #openaccess https://lnkd.in/gncJ8NHA
Treatment Targets Should Influence Choice of Infliximab Dose Intensification Strategy in Inflammatory Bowel Disease: A Pharmacokinetic Simulation Study - BioDrugs
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This study in BioDrugs compared plasma exposure of tocilizumab with intravenous vs. subcutaneous administration regimens in kidney transplant recipients with chronic active antibody-mediated rejection (CAAMR). #pharmacokinetics #Tocilizumab #kidneytransplantrecipient https://lnkd.in/gmJDm2Vi
A Population Pharmacokinetic Model of Tocilizumab in Kidney Transplant Patients Treated for Chronic Active Antibody-Mediated Rejection: Comparison of Plasma Exposure Between Intravenous and Subcutaneous Administration Schemes - BioDrugs
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Noninvasive skin imaging techniques provide new means for rapid, objective, quantitative, and accurate evaluation of acne scars. #acnescars #imaging https://lnkd.in/ggh-davW
Advances in the Application of Noninvasive Skin Imaging Techniques in Acne Scars - American Journal of Clinical Dermatology
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This case-control study in the US by Gil Yosipovitch and colleagues demonstrated that patients with chronic spontaneous urticaria (CSU) may be at an increased risk for comorbid cardiac conditions. #ChronicSpontaneousUrticaria #comorbidities #heartdisease https://lnkd.in/gGWt-igP
Association of Cardiovascular Disease and Chronic Spontaneous Urticaria: A Case–Control Study - American Journal of Clinical Dermatology
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This review describes dapsone and its diverse applications in dermatology practice. #dermatology #Dapsone #leprosy #openaccess https://lnkd.in/gCC5bewS
Dapsone Use in Dermatology - American Journal of Clinical Dermatology
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This review in BioDrugs highlights the synergistic potential of local therapies and CAR T cell treatment to overcome challenges posed by solid tumors and provides an overview of current research combining these two strategies. #carttherapy #SolidTumors #combinationtherapy https://lnkd.in/ggJ5Uju6
Prospects of Synergy: Local Interventions and CAR T Cell Therapy in Solid Tumors - BioDrugs
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Read the top downloaded papers in BioDrugs in 2024. A special thanks to the contributing authors, including Achim Prof. Dr. Aigner, William Strohl, Sivan Cohen, Serge Muyldermans, Beate Bittner, Allison Keeler, Danielle Stanisic, Rakesh N. Veedu https://lnkd.in/gaB_hcF2
Top Downloaded Papers in 2024
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Alexa B. Kimball, and colleagues review the current research on targeted therapies for hidradenitis suppurativa, including FDA-approved biologics and therapies in phase III and II trials. #hidradenitisSuppurativa #biologics #JAKinhibitors https://lnkd.in/g-SNJNhY
Hidradenitis Suppurativa: New Targets and Emerging Treatments - American Journal of Clinical Dermatology
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This AdisInsight report in BioDrugs summarizes the milestones in the development of insulin icodec leading to this first approval for diabetes mellitus. https://lnkd.in/g8gCXc3q #insulin #diabetes #firstapproval
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Editor In Chief at Adis, Springer Nature
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