Life Sciences Tech Network - Berlin’s Post

Do some grant reviewers have preferences for animal experiments? Does this impact the funding of grants that propose human-based in vitro approaches? What can we do to address this growing concern? 📌SAVE THE DATE 📌 for a virtual workshop discussing these topics on May 16th! Watch this space for more details!

SAVE THE DATE! Exciting news for those interested in alternative large animal models! Join us for a one-day scientific conference to discuss minipig care, handling, and use in biomedical research. Register now: https://lnkd.in/dcibBeg9 #ScientificConference #MinipigResearch #BiomedicalResearch #AnimalModels

You can't miss tomorrow's COST_TEATIME webinar! I will talk about the role of #Metadata in nonclinical, in-vivo biomedical research and animal welfare. We defined a minimal set of metadata (MNMS) that can be shared across all in-vivo biomedical experiments. This solution is bound to have a large, positive impact on biomedical research, animal welfare, and behavior discovery! Now is the moment for us to fully exploit the global potential hidden in our data. Let's openly share it using interoperable formats, fostering a global community of researchers who can flourish together through collaborative efforts. Following the MNMS we will empower in-silico discovery, revolutionizing the way we approach scientific advancements and embracing the principles of Replace, Reduce, and Refine! Link to register: https://lnkd.in/eBQpYwA3 Paper: https://lnkd.in/eGfSrqp5 #3R #animalwefare #reproducibility #opendata Co-authors: Stefano Gaburro, PhD, CCP | Anastasios Moresis | Eoin O'Connor | Alexandra Bannach-Brown, PhD | Giorgio Rosati | Gunnar Flik | Sophie Bromilow | Fabrizio Scorrano Many thanks to Vootele Voikar and COST_TEATIME for the invitation! PS This is what a generative AI produces when the input is: nonclinical research, and metadata :)

The #mdcBerlin is getting on #BOARD24! "𝗕𝗢𝗔𝗥𝗗" stands for 𝗕e 𝗢pen about 𝗔nimal 𝗥esearch 𝗗ay. This global social media campaign is organized by the European Animal Research Association (EARA) and supported by the wider biomedical community, both public and private. Below, you will find several #research findings from some of our labs that would not have been possible without animals. Transparency about #AnimalResearch is a fundamental value for us, as it is for #EARA, all of its members, and participants of today's campaign. Get on #BOARD24!   Learn more about the Max Delbrück Center's open and transparent communication regarding animal research: https://lnkd.in/eci5ijT3 𝗔 𝗻𝗲𝘄 𝗰𝗵𝗮𝗻𝗻𝗲𝗹 𝗳𝗼𝗿 𝘁𝗼𝘂𝗰𝗵 | Every hug requires touch perception. To understand its molecular basis, a team led by MDC-Berlin scientist Gary Lewin used mice – and discovered an ion channel associated with touch that is also a possible target for #PainTherapy. More information 👉 https://lnkd.in/dVWtHu9i 𝗚𝗲𝗻𝗲 𝗲𝗱𝗶𝘁𝗶𝗻𝗴 𝗽𝗿𝗲𝗰𝗶𝘀𝗲𝗹𝘆 𝗿𝗲𝗽𝗮𝗶𝗿𝘀 𝗶𝗺𝗺𝘂𝗻𝗲 𝗰𝗲𝗹𝗹𝘀 | Imagine you could help infants with a rare #ImmuneDisease by repairing a faulty gene in their T cells. The gene scissors #CRISPR-Cas9 would need to be precise –and MDC-Berlin's Klaus Rajewsky has shown that it’s possible in mice. More information 👉 https://lnkd.in/eQ9--zDD 𝗛𝗼𝘄 𝘀𝗸𝗮𝘁𝗲𝘀 𝗹𝗲𝗮𝗿𝗻𝗲𝗱 𝘁𝗼 𝗳𝗹𝘆 𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝘄𝗮𝘁𝗲𝗿 | A new way of thinking about how genomes evolve: Instead of looking at variations in the #DNA sequence, former MDC-Berlin scientist Darío Lupiáñez focuses on the 3D structures the DNA is folding into. He discovered how skates learned to fly through water. More information 👉 https://lnkd.in/erEAMuGq 𝗛𝗲𝗮𝗿𝘁 𝗿𝗲𝗽𝗮𝗶𝗿 𝘃𝗶𝗮 𝗻𝗲𝘂𝗿𝗼𝗶𝗺𝗺𝘂𝗻𝗲 𝗰𝗿𝗼𝘀𝘀𝘁𝗮𝗹𝗸 | Unlike humans, #zebrafish can regenerate their hearts after injury. They owe this ability to crosstalk between their autonomous nervous and immune systems, a team of MDC-Berlin group leader Suphansa Sawamiphak discovered studying zebrafish larvae. More information 👉 https://lnkd.in/e5dbe-H7

Complement Animal Research In Experimentation Here are the NIH “Complement-ARIE Challenge” Prize Winners! Congratulations! The National Institutes of Health has announced the winners of the Common Fund Complement Animal Research In Experimentation (Complement-ARIE) crowdsourcing competition for innovative ideas on New Approach Methodologies, or NAMs. The Complement-ARIE Challenge prize competition offered $1,000,000 in total prize money to diverse teams with ideas for new ways of using NAMs to conduct basic research, uncover disease mechanisms, and translate knowledge into products and practice. https://lnkd.in/dP3h2CtE

It's Microphysiological Systems Monday! Microphysiological systems (MPS) are currently considered most promising for early discovery studies prior to animal research and for use in conjunction with animal or human models. If you aren't sure what an MPS is, or you want to become more familiar with a specific organ model, our Microphysiological Systems initiative has created a webinar series that provides an introduction to MPS and an overveiw of nine different organ systems. Access the webinars here: https://lnkd.in/eUSCdTUG

Researchers, policimakers, funders of biomedical research, you might want to join us! Find out what it takes to change your research practice towards non animal models. Watch the preview: Webinar (free) 29/2 13h15-15h00 - TEN HELPATHONS - organizing trust

I had to read the title thrice before understanding it. Yes, because in their last paper, Ludwig et al. make a point that Adhesive Tape Impression (ATI) is better than trichogram and Wood's lamp for the fungal culture for diagnosis of dermatophytosis. What to say, in today's technological world, sometimes is the beauty of the simple things that impresses us. If you ever wondered what ATI is, here is a guideline from the University of Bristol: https://lnkd.in/ecgPPW58 Here is the link to the article: https://lnkd.in/eCBRUqCV Want to know what the top 5 mistakes in preclinical animal health studies are? Steal our eBook here: https://lnkd.in/gGn5EChK ————————— I am Davide - Founder & CEO of Lab4Paws. With my life science company I help #AnimalHealth scientists develop therapeutic & diagnostic solutions for companion animals and work to reduce animal testing for human drug development. Like my content? Click my name + follow + 🔔

Today, April 24th, is the world day for Laboratory animals. This day was instituted in 1979 to draw attention to animal research. At the Swedish 3Rs Center we work to replace, reduce and refine animal research. Here are a few recent things we have done within our mission: 📌 Webpage listing components for animal-free cell culture https://lnkd.in/dfuKceXX 📌 Supporting material in acclimatization of mice and rats (in Swedish) https://lnkd.in/dB5BC6uw 📌 Supporting material in choosing method of euthanasia for mice https://lnkd.in/dES5zjhV 📌 Webpage of online resources for development, evaluation and formal validation of in vitro methods https://lnkd.in/dZ3MJakr 📌 Statement and supportive material on tail free mouse handling https://lnkd.in/dDNUEFPC 📌 Films about replacing animal models https://lnkd.in/dxHY-inS 📌 Discussion material to work with Culture of Care (in Swedish) https://lnkd.in/d2wyj-RZ 📌 Document of good examples of refinement in Sweden (in Swedish) https://lnkd.in/d6QSbQXi

Can AI Transform Cell Diagnostics and Biomarker Discovery? 🔍🤖 Ai is changing the way biomarker discovery is performed, and Animal Health Scientists will be the first to benefit from it (if they work with the right partners) I discussed it in more detail in my previous livestream : https://lnkd.in/eJKYZRw7 Curious to learn about the 5 mistakes to avoid in preclinical animal health studies? Steal our last eBook free of charge: https://lnkd.in/gGn5EChK ————————— I am Davide - Founder & CEO of Lab4Paws. With my life science company I help #AnimalHealth scientists develop therapeutic & diagnostic solutions for companion animals and work to reduce animal testing for human drug development. Like my content? Click my name + follow + 🔔