𝗠𝗲𝗲𝘁𝗶𝗻𝗴 𝗢𝗿𝗴𝗮𝗻𝗶𝘇𝗲𝗿: 𝗜𝘀 𝘁𝗵𝗲𝗿𝗲 𝗮 𝗱𝗼𝗰𝘁𝗼𝗿 𝗶𝗻 𝘁𝗵𝗲 𝗵𝗼𝘂𝘀𝗲?
𝘠𝘰𝘶𝘳 𝘔𝘋 𝘧𝘳𝘪𝘦𝘯𝘥: 𝘠𝘦𝘴, 𝘐'𝘮 𝘢𝘯 𝘦𝘮𝘦𝘳𝘨𝘦𝘯𝘤𝘺 𝘱𝘩𝘺𝘴𝘪𝘤𝘪𝘢𝘯. 𝘏𝘰𝘸 𝘤𝘢𝘯 𝘐 𝘩𝘦𝘭𝘱?
𝗠𝗲𝗲𝘁𝗶𝗻𝗴 𝗢𝗿𝗴𝗮𝗻𝗶𝘇𝗲𝗿: 𝗠𝘆 𝗮𝗽𝗼𝗹𝗼𝗴𝗶𝗲𝘀. 𝗟𝗲𝘁 𝗺𝗲 𝗯𝗲 𝗰𝗹𝗲𝗮𝗿𝗲𝗿. 𝗔𝗿𝗲 𝘁𝗵𝗲𝗿𝗲 𝗮𝗻𝘆 #VariantClassification 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝘀𝘁𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗵𝗼𝘂𝘀𝗲? 𝗪𝗲 𝗵𝗮𝘃𝗲 𝗮𝗻 𝘂𝗿𝗴𝗲𝗻𝘁 #ClinicalGenetics 𝘀𝗶𝘁𝘂𝗮𝘁𝗶𝗼𝗻 𝘁𝗼 𝗱𝗲𝗮𝗹 𝘄𝗶𝘁𝗵.
𝘠𝘰𝘶 𝘢𝘯𝘥 𝘺𝘰𝘶𝘳 𝘤𝘰𝘭𝘭𝘦𝘢𝘨𝘶𝘦𝘴 𝘴𝘵𝘳𝘪𝘥𝘪𝘯𝘨 𝘧𝘰𝘳𝘵𝘩 𝘸𝘪𝘵𝘩 𝘥𝘦𝘵𝘦𝘳𝘮𝘪𝘯𝘢𝘵𝘪𝘰𝘯: 𝘏𝘰𝘸 𝘤𝘢𝘯 𝘸𝘦 𝘩𝘦𝘭𝘱?
𝗠𝗲𝗲𝘁𝗶𝗻𝗴 𝗢𝗿𝗴𝗮𝗻𝗶𝘇𝗲𝗿: *𝘄𝗲𝗲𝗽𝗶𝗻𝗴 𝘄𝗶𝘁𝗵 𝗴𝗿𝗮𝘁𝗶𝘁𝘂𝗱𝗲* 𝗙𝗼𝗹𝗹𝗼𝘄 𝗺𝗲 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝘀𝘁𝘀. 𝗜𝘁'𝘀 𝘁𝗶𝗺𝗲 𝘁𝗼 𝘂𝗽𝗱𝗮𝘁𝗲 𝘁𝗵𝗲 𝘃𝗮𝗿𝗶𝗮𝗻𝘁 𝗰𝗹𝗮𝘀𝘀𝗶𝗳𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝘀𝘁𝗮𝗻𝗱𝗮𝗿𝗱𝘀 𝗮𝗻𝗱 𝗴𝘂𝗶𝗱𝗲𝗹𝗶𝗻𝗲𝘀.
This is it. This is your moment. #VariantClassification 𝗦𝗰𝗶𝗲𝗻𝘁𝗶𝘀𝘁𝘀 assemble!
See: https://lnkd.in/g-zfAmwA
Corporate Workshop: ACMG/AMP/CAP/ClinGen DRAFT Standards for Sequence Variant Classification v4.0
Join members of the ClinGen community at the Association for Molecular Pathology (AMP) 2023 Annual Meeting & Expo in Salt Lake City.
Wednesday, November 15, 2023 I 4:00 PM – 4:50 PM MST
Steven Harrison, PhD FACMG & Heidi Rehm
It is FREE to attend Corporate Workshop Day; however, this year registration is REQUIRED. If you are already registered for the AMP Annual Meeting – as an attendee or booth staff – please pick up your badge prior to attending any Corporate Workshops. If you are not registered for the AMP Annual Meeting, you will need to register for Corporate Workshop Day. Registration is FREE, you will just need to complete the registration form linked below and pick-up your badge from the Main registration area.
Association for Molecular Pathology (AMP), ClinGen Resource, ACMG - American College of Medical Genetics and Genomics, College of American Pathologists (CAP)#ClinicalGenetics#Genetics#Genomics#PrecisionMedicine#RareDisease#FDA#LDT#LDTs#CAP#CLIA#PrecisionOncology#GCchat#ELEVATEGENETICS
🔎 Join our expert panel as they discuss the current and future perspectives for bispecific antibodies in #MultipleMyeloma.
The symposium was led by Sagar Lonial, Winship Cancer Institute of Emory University, Atlanta, US. He was joined by guest speakers Naresh Bumma, Amrita Krishnan, and Sergio Giralt; together they explored BCMA-directed and alternative novel strategies using bispecific antibodies and the practical management of adverse events with immunotherapies.
The speakers used example clinical cases to emphasize how their findings can be applied to real-world scenarios.
A must watch!
Don’t miss out!
https://loom.ly/P-xfbwghttps://loom.ly/inOoec8https://loom.ly/KQW4lAUhttps://loom.ly/_VtODJ4#bispecific#myeloma#mmsmEuropean School of Haematology (ESH)
Watch Sagar Lonial’s presentation from our latest symposium on the current and future perspectives for bispecific antibodies in #MultipleMyeloma.
Key points covered in this presentation include:
▪️ The increasing options for patients with relapsed/refractory multiple myeloma
▪️ The mechanism of action of BsAbs works by binding to CD3 and a plasma cell target
▪️ BsAbs bring T-cells in close proximity to malignant tumor cells, resulting in #myeloma cell death
▪️ Rational targets include BCMA, GPRC5D, and FcRH5
https://loom.ly/P-xfbwg#mmsm
Travel Clinical Pharmacist, International Health Consultant at SF US-Vietnam Sister City Committee, NuSkin AgeLOC Anti-Aging & Red LED Light, Intl Guest Speaker, Member NSS & MARS Societies
"Non-invasive tests may actually hold more predictive value than imaging tests, which makes sense because they can detect disease at a much lower level...perhaps this is an opportunity to improve the way we define remission."
Mark Roschewski discusses the findings and implications from his recent study presented at #ash23 that compared the performance of PhasED-Seq ctDNA vs. PET/CT scans for response assessment after frontline therapy for aggressive #DLBCL.
These findings require us to rethink how we best measure response in lymphoma - and this is particularly critical for clinical trials. When used in conjunction with standard PET/CT imaging, PhasED-Seq's ultra-sensitive ctDNA platform may be a more accurate measure of response, and thereby, a more confident indicator of therapeutic efficacy for drug development and approvals.
Watch the full video here: https://lnkd.in/dqJvbfw9#mrd#ctdna#lymphoma#clinicaltrials
Check out my interview with "The Onc Doc": Sanjay Juneja, M.D. on his podcast "Target Cancer."
We discuss how the SAGE Oncotest can guide you and your oncologist to identify the best treatment for your very unique cancer.
Don't miss our interview with Sanjay Juneja, M.D.
We're covering several important topics:
1. How to catch cancer much earlier to "live long and prosper!"
2. Why current diagnostics, including genomic testing, fall short of finding the best therapy for you.
3. How the SAGE Oncotest can help you to receive the most effective treatment.
https://lnkd.in/g9AAuH8v
Many thanks to all involved in this work. The central observation of a PGF2a induced phenotype change is a fascinating one. Raises questions of whether this is unique to PGF2a or also applies to other agonists of human labour such as oxytocin or PGE2. We also need to understand the relationship of these changes to the effects of progesterone.
Insights on how prostaglandin F2α initiates labor, by transforming the myometrium from a myofibroblast to smooth muscle, pro-labour like state. #maipltx celebrates this important scientific discovery through a collaboration between former #ferring colleagues and the Andrew Blanks lab!