Metrion Biosciences’ Post

View organization page for Metrion Biosciences, graphic

4,444 followers

Our new neuroscience brochure is now available for you to download for insight into: 💡Panel of models with increasing complexity and translational relevance: • Cell lines for central and peripheral nervous system targets. • Primary neuronal cultures, such as dissociated cortical, trigeminal or DRG. • CNS drug discovery to understand the effects of test compounds on brain slice tissue. • Human iPSC-derived neurons. 💡Range of assay methodologies to help you investigate the mechanism of action for pre-clinical compounds, confirm compound effects, address the neurotoxicity of compounds and assess the effects of compounds on a range of excitability parameters: • Heterologous cell lines and integrative assays. • Selectivity and safety profiling of lead compounds and IND candidates. • Translational assays: central and peripheral neuronal firing, and native ion channel screening assays. 💡Studying ion channels on the lysosomal membrane. 💡CNS drug discovery to understand the effects of test compounds on brain slice tissue. 📄Case study: Multi-assay high-throughput repurposing screen for rare epilepsy mutation in KCNC1 gene. As a specialist preclinical drug discovery CRO, we pride ourselves on delivering high quality data, on time and on budget. Find out more about our neuroscience services and download the brochure: https://hubs.la/Q02GXJCC0 Contact us to request a meeting or quote: https://hubs.la/Q02GXhnX0 #neuroscience #drugdiscovery #cro #ionchannels #lifesciences #cns #electrophysiology

  • No alternative text description for this image

To view or add a comment, sign in

Explore topics