This video provides a concise overview of a study on kidney tissue engineering, focusing on preclinical models of renal failure. Conducted by Milad Mirmoghtadaei et al., it systematically reviews the efficacy of various biomaterials in kidney reconstruction. The research examines the use of natural, synthetic, and hybrid scaffolds, with or without cells and growth factors, across 19 studies involving 937 animals. Findings indicate that combining biomaterials with bioactive moieties and cell seeding shows promise in improving renal function and regeneration, highlighting a step forward in addressing renal insufficiency and the limitations of organ transplantation. Full-Text: https://lnkd.in/eaZsQQVe https://lnkd.in/e8jPVaxR #TissueEngineering #KidneyRegeneration #RegenerativeMedicine #RenalFailureSolutions #BiomaterialsInMedicine #PreclinicalModels #KidneyHealth #StemCellResearch #BiomedicalEngineering #RenalInsufficiency #OrganTransplantation #SyntheticScaffolds #BioactiveMaterials #CellTherapy #MedicalInnovation #HealthcareResearch #AnimalModelStudies #Biotechnology #ClinicalTrials #FutureMedicine
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𝐆𝐥𝐨𝐛𝐚𝐥 𝐇𝐮𝐦𝐚𝐧 𝐎𝐬𝐭𝐞𝐨𝐛𝐥𝐚𝐬𝐭𝐬 𝐌𝐚𝐫𝐤𝐞𝐭: 𝐆𝐥𝐨𝐛𝐚𝐥 𝐒𝐢𝐳𝐞, 𝐒𝐡𝐚𝐫𝐞 & 𝐅𝐨𝐫𝐞𝐜𝐚𝐬𝐭 𝟐𝟎𝟑𝟒 ▶𝐑𝐞𝐪𝐮𝐞𝐬𝐭 𝐟𝐨𝐫 𝐒𝐚𝐦𝐩𝐥𝐞 𝐏𝐃𝐅: https://lnkd.in/giJBwCjm Human osteoblasts are specialized cells crucial for bone formation, originating from mesenchymal stem cells and playing a vital role in the development, maintenance, and repair of the skeletal system. They synthesize bone matrix and facilitate bone mineralization, helping maintain bone density and structure. This report offers a comprehensive analysis of the global Human Osteoblasts market, providing both quantitative and qualitative insights by company, region, type, and application. It explores market competition, supply and demand trends, and key factors driving demand across various markets. The report also includes company profiles, product examples, and market share estimates for selected leaders in 2024. 𝐒𝐞𝐠𝐦𝐞𝐧𝐭𝐚𝐭𝐢𝐨𝐧: ▶𝐁𝐲 𝐓𝐲𝐩𝐞: Human Cell Culture, Osteoblast Cell Lines. ▶𝐁𝐲 𝐀𝐩𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧: Hospitals, Specialty Clinics, Ambulatory Surgical Centers. ▶𝐆𝐞𝐨𝐠𝐫𝐚𝐩𝐡𝐲: North America, Europe, APAC, Latin America, and Middle East & Africa. 𝐊𝐞𝐲 𝐏𝐥𝐚𝐲𝐞𝐫𝐬 𝐜𝐨𝐯𝐞𝐫𝐞𝐝: Sigma-Aldrich, Athersys., Cerapedics Inc., Cryolife Inc, Cytori Therapeutics Inc, U.S. Stem Cell, Inc, Vericel® Corporation, Wright Medical, Biocomposites, BD, Zimmer Biomet, PromoCell. #GlobalHumanOsteoblasts #OsteoblastsMarket #BoneRegeneration #TissueEngineering #StemCellResearch #BoneHealthInnovation #OrthopedicResearch #fatposglobal
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On average, 16 lives are lost every day due to a lack of organ transplants and 9 out of 10 drugs in development fail in clinical stages due to poor models for testing. But what if you could create human tissue – or even organs? Or better biological models for drug testing? While the creation of human organs for transplantation is still in the early stages, 3D bioprinting of biological tissue like bone, skin cells and blood vessels for testing and research purposes is possible today, thanks to companies like Sweden-based CELLINK. Intertek has supported CELLINK by testing their third generation LUMEN X bioprinter, which provides researchers all over the world with the possibility to print tissue models to replace animal testing and make their data more reliable. Using the LUMEN X 3D bioprinter, researchers have even managed to biofabricate a cornea! The LUMEN X joins the ranks of products tested by Intertek for EMC and harmful UV-rays. We are proud to be helping innovative manufacturers, like CELLINK, safely bring groundbreaking new products to market that are making a difference to so many people's lives. www.intertek.com/amazed
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Magnetic Activated Cell Sorting (MACS) Magnetic Activated Cell Sorting (MACS) is a technique used in biological and medical research to separate cells based on specific surface markers or properties. In MACS, cells are labeled with magnetic nanoparticles conjugated to antibodies that bind to target molecules on the cell surface. Then, the cell suspension is passed through a magnetic field, causing the labeled cells to be retained while unlabeled cells flow through. By manipulating the magnetic field, labeled cells can be separated from the mixture and collected for further analysis or use. MACS is commonly used in various applications such as isolating specific cell populations for research, purifying cells for transplantation therapies, and enriching rare cell types from complex samples. It offers a rapid, efficient, and gentle method for cell separation with high purity and viability.
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🔬 Research Alert! published in #DrugDevIndPharm. 2023, VOL. 49, NO. 2, 240–247 🌟"Hesperetin-loaded polymeric nanofibers: assessment of bioavailability and neuroprotective effect "🌟 👉 This research article focuses on the assessment of the bioavailability and neuroprotective effect of hesperetin (Hesp)-loaded polymeric nanofibers. The study involved preclinical experiments conducted on Wistar rats, where different treatments were administered to evaluate their effects on memory and brain health. The results showed that Hesp-loaded nanofibers significantly improved bioavailability and protected rats from scopolamine-induced amnesia. The nanofibers also reduced acetylcholinesterase activity, lipid peroxidation, degeneration, and inflammation in the hippocampus. 📖 Read the full article here: https://lnkd.in/gkrzZR-n
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At Nomisma Healthcare PVT. LTD. we are proud to be at the forefront of biomedical innovation, manufacturing high-quality PEG-PLGA Block Copolymers. These advanced materials combine PEG’s hydrophilicity with PLGA’s biodegradability, making them a game-changer in various medical applications. 🔬 Key Applications: - Drug Delivery Systems: Ideal for formulating nanoparticles, micelles, and hydrogels for controlled and targeted drug delivery. - Tissue Engineering: Essential in developing scaffolds for tissue repair and regeneration. - Medical Devices: Used in the creation of bioresorbable implants, stents, and sutures. - Cancer Therapy: Designed for nanocarriers that deliver chemotherapeutic agents directly to tumor sites. Transform your research and product development with our PEG-PLGA Block Copolymers. Reach out to us at info@nomismahealthcare.com to learn more or to place an order. #NomismaHealthcare #Biopolymers #DrugDelivery #TissueEngineering #MedicalDevices #CancerTherapy #Innovation
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🔬 𝐓𝐫𝐚𝐧𝐬𝐟𝐨𝐫𝐦𝐢𝐧𝐠 𝐓𝐫𝐚𝐧𝐬𝐩𝐥𝐚𝐧𝐭 𝐒𝐮𝐜𝐜𝐞𝐬𝐬: 𝐓𝐡𝐞 𝐇𝐋𝐀 𝐓𝐲𝐩𝐢𝐧𝐠 𝐓𝐫𝐚𝐧𝐬𝐩𝐥𝐚𝐧𝐭 𝐌𝐚𝐫𝐤𝐞𝐭 🔬 𝐂𝐥𝐢𝐜𝐤 𝐇𝐞𝐫𝐞, 𝐓𝐨 𝐆𝐞𝐭 𝐅𝐫𝐞𝐞 𝐒𝐚𝐦𝐩𝐥𝐞 𝐑𝐞𝐩𝐨𝐫𝐭 https://lnkd.in/gP3x98Bj The HLA Typing Transplant Market is at the forefront of advancing transplant medicine, ensuring better compatibility and outcomes for patients undergoing organ and tissue transplants. With cutting-edge technologies and precision diagnostics, HLA typing is revolutionizing the field of transplantation. 🌟 Key Highlights: Precision Matching: Advanced HLA typing technologies provide highly accurate and detailed matching of donor and recipient HLA profiles, significantly reducing the risk of transplant rejection. Innovative Techniques: The market is witnessing the development of novel techniques such as next-generation sequencing (NGS) and polymerase chain reaction (PCR), which offer faster and more reliable results. Improved Outcomes: Better HLA matching leads to improved graft survival rates and overall patient outcomes, enhancing the quality of life for transplant recipients. 📈 Market Dynamics: Growing Transplantation Needs: The increasing number of organ and tissue transplants worldwide is driving demand for precise HLA typing to ensure successful transplantation. Technological Advancements: Continuous innovations in HLA typing methodologies are making the process more efficient, accurate, and accessible. Regulatory Support: Supportive regulatory frameworks and guidelines are facilitating the adoption of advanced HLA typing techniques in clinical practice. #Company Immucor, Inc. Illumina Thermo Fisher Scientific Biofortuna Bio-Rad Laboratories GenDx HistoGenetics Linkage Biosciences | A Thermo Fisher Scientific Brand Omixon #Type Non-Molecular Assays Molecular Assays #Application Hospitals Academic and Research Institutes #HLATyping #TransplantMedicine #PrecisionMedicine #HealthcareInnovation #PatientCare #OrganTransplant #MedicalResearch #GlobalHealth #LinkedInPost
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Light-Sheet Microscopy awardee Michael Welte, PhD published in Advanced Healthcare Materials: "Sided Stimulation of Endothelial Cells Modulates Neutrophil Trafficking in an In Vitro Sepsis Model." https://ow.ly/FyHz50Tm8Av #published #phd #lightsheet #microscopy #article #sepsis #therapeutics #biology #molecularbiology #cellbiology
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🔬📚 Exciting News! 📚🔬 Our first HTS paper was recently published in Advanced Healthcare Materials, with Maximilian Fusenig, PhD, Lisa Grönnert and me as joint first authors! https://lnkd.in/eD75AvPT In a close collaboration between the Leibniz-Institut für Polymerforschung Dresden (IPF) and the Ophthalmology Team at Roche, we developed Precision Culture Scaling (PCS-X), a statistics-driven approach to develop 3D cell cultures for high-throughput screening applications. Our methodology opens new avenues for creating HTS models of healthy and diseased tissues for drug discovery and individualized therapies. 🚀 Manfred Maitz, Maria Alejandra Ramirez Martinez, Manja Wobus, Uwe Freudenberg, Martin Bornhäuser, Jens Friedrichs, Peter Westenskow, Carsten Werner #Science #Research #DrugDiscovery #Vasculogenesis #HighThroughput
Precision Culture Scaling to Establish High‐Throughput Vasculogenesis Models
onlinelibrary.wiley.com
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Associate Professor| Department of Pharmaceutical Chemistry| Bengal college of Pharmaceutical Sciences and Research|Pharmaceutical Chemistry| Computational Chemist| GPAT-2015| NIPER-2015| CSIR|
🔶🔶 𝗖𝗮𝗹𝗹 𝗳𝗼𝗿 𝗕𝗼𝗼𝗸 𝗖𝗵𝗮𝗽𝘁𝗲𝗿 𝗖𝗼𝗻𝘁𝗿𝗶𝗯𝘂𝘁𝗶𝗼𝗻𝘀: 🔶🔶 Dear Academicians, Scientists, and Researchers, We are thrilled to announce the call for Book Chapters for the upcoming book, entitled "2D Nanomaterials in Biomedical Applications: Therapeutics, Diagnostics, and Regenerative Medicine" to be published by NOVA Publications. We invite you and your research team to contribute a chapter to this upcoming publication. This book will delve into the role of 2D nanomaterials, their unique properties, synthesis techniques, and how they can be tailored for drug delivery systems, bioimaging, diagnostics, tissue engineering, regenerative medicine, antimicrobial applications, and cancer therapy. The book will also address safety, toxicological aspects, and the challenges associated with clinical translation. Recent advancements in 2D nanomaterials have significantly impacted biomedical applications, offering innovative solutions in therapeutics, diagnostics, and regenerative medicine. These nanomaterials, such as graphene, transition metal dichalcogenides (TMDs), black phosphorus (BP), MXenes, and hexagonal boron nitride (h-BN), have unique properties like high surface area, biocompatibility, tunable surface chemistry, and exceptional electronic and photonic characteristics. Please find the attached flyer for more information on submission guidelines and deadlines. We look forward to your valuable contributions. Share your topic of choice, email ID, and contact number with bookproposal94@gmail.com. ✉ Best Regards Editors
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🌟 Revolutionairy Biotechnology: Discover Gelnest Matrix Products! 🧬 GelNest™ Matrix is derived from mouse tumor tissue and contains extracellular matrix components such as laminin, type IV collagen, heparan sulfate proteoglycans, and more. These components support cell adhesion, differentiation, and proliferation, providing signals for these processes. Additionally, they simulate the characteristics of the basement membrane in the physiological environment, enhancing the success rate and effectiveness of cell culture. In addition to the matrix components, GelNest™ Matrix is rich in various growth factors. These growth factors promote cell differentiation, proliferation, and migration, mimicking cellular signaling pathways and interactions in the physiological environment. GelNest™ Matrix has a wide range of applications, particularly in tissue engineering, cell culture, and research. It can be used for organoid culture, stem cell differetiation, angiogenesis, migration or invasion assays, and in vivo tumor studies. Contact us to receive more product information, prices or send us your sample request to info@labdeal.nl Wuxi NEST Biotechnology Co.,Ltd #NEST #labdeal #laboratory #laboratorium #lifesciences #Matrigel #corning #2dculturecoating #celltherapy #cellandgenetherapy #organoids #organoid #invivo #invivotumor #invitro #invitrodiagnostics #stemcells #stemcelltherapy #stemcell #stemcellresearch
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