MilliporeSigma’s Post

At Merck Life Science, we're proud to be playing a crucial role in shaping the future of global health. Our commitment to impact life and health with science is evident in every step we take, like the recent signing of a non-binding Memorandum of Understanding with Afrigen Biologics (Pty) Ltd, as we support the development of mRNA vaccine technology manufacturing capabilities. mRNA technology is a breakthrough in vaccination due to its ability to rapidly develop adaptable, safe, and highly effective vaccines against various pathogens, offering significant advancements in public health responses. We are dedicated to making a meaningful impact and improving health outcomes for South Africa and low- and middle-income countries (LMICs). #life #science #mRNA #vaccine #health #impact #technology 

A project dear to my heart, and a proof point of how determined we are to contribute to the empowerment of the life science industry on a global scale - this time with the mRNA platform technology!" :-) #MerckLifeScience #Afrigen #MedicinePatentPool #mRNA #TechnologyTransfer #Partnerships

Boosting antibody purification productivity and reducing clinical trial costs are major trends impacting the therapeutic antibody drug space. Read how AGC Biologics implemented a fully single-use manufacturing suite to accomplish both. Great work! https://lnkd.in/gvUbTtCh #antibodies #proteinpurification

Updates to the Changing Therapeutic Landscape 2023: - A minor revenue contraction is noted, attributed to decreased COVID vaccine utilization. - Biologics, including mAb, peptides, and vaccines, are experiencing ongoing growth. - The landscape of top revenue therapies is evolving, showcasing a dynamic shift.

Accelerate your biologics candidate selection with the ability to measure affinities in solution from samples like crude lysate or cell media. Learn how the new Human Fc labeling kit and Spectral Shift technology are simplifying affinity screening workflows. https://lnkd.in/gNXA6AHw

Register today for "Innovative Strategies for the Development & Manufacture of Challenging Bispecific Antibodies and Fusion Proteins." Novel or next-generation biologics such as bispecific antibodies and fusion proteins present unique challenges in their development and manufacturing processes due to complex formats, suboptimal stability, product aggregation, or low productivity. These issues impact product quality and consistency, as well as the ability to develop efficient and scalable processes. Successfully addressing these challenges while reducing cost of goods requires the strategic utilization of advanced technologies, appropriate analytical methods, extensive experience, and adopting a proactive approach to de-risk the drug development efforts of this emerging class of biotherapeutics. This webinar will review WuXi Biologics’ advanced solutions for overcoming the myriad of obstacles associated with the development and manufacture of these complex biologics. Register here: https://lnkd.in/dnU9cix9

⏳ Final week to save up to $1200 on the Advancing Purification for Complex Biologics Summit (28-30th November | Philadelphia, PA). 💵 Our early-registration discount concludes this Friday 22nd September. 'As inflation rises, biopharma leaders excelling drug development are in the search for efficient solutions and software to boost downstream processing efficiency' 💊 It is clear there is value to be found in learning how others have applied advanced multivariate analytics, automated platform adjustments, digital twins and DoE optimizations to eliminate bottlenecks to their project delivery caused by personnel constraints and material costs. Join us as we host 80+ experts in Purification, Downstream Processing, Process Development, Data Science, and Chromatography to strive for robust and efficacious purification, platform the ‘un-platformable’ and ensure rapid delivery of high-quality medicines to clinical trials and the market. To learn more on this data-driven summit and how you can register by the end of the week to save up to $1200 on attendance, check out the post below or our website using the following link: https://ter.li/rejnri

Did you know about a local mRNA production facility and expertise right here in Atlantic Canada? Read the article to learn more....

Charged variant analysis is an important tool to understand the bio-functionality of biologics. In this on-demand webinar, Catalent experts discuss challenges involved with the isolation, purification and characterization of charged variants of biotherapeutics, including monoclonal antibodies and fusion proteins. https://ow.ly/7jcq50QpiCK

Live webinar! March 20th, 2024 @ 11 AM ET Impurities can induce immune reactions in patients, forcing scientists to restart process development. Thus, detecting and removing biopharmaceutical impurities such as host cell proteins is important for biotherapeutic development and production, and necessary for maintaining drug efficacy and ensuring patient safety. In this webinar brought to you by Cytiva, Andrew Hamilton and Joe Hirano will discuss how to identify, detect, and measure impurities in biologics manufacturing. Register here #AD: https://ow.ly/cKoC50QEbNV