Moira Gunn’s Post

Learn more about a Phase 3 Clinical Trial Launched from Johns Hopkins of NAC for RP Patients in this short podcast!

"Miscommunication leads to misunderstanding' A phenomenon particularly prevalent in our industry. We often encounter instances where genetic terminology is used inaccurately, leading to confusion and misinterpretation. For instance, the term 'DNA' might be used to refer to a microsatellite parentage certificate, while 'haplotype' is often used to refer to a genetic defect. 'Haplotype' stands out as one of the most misconstrued terms in our field. Simply a sequence of alleles, haplotypes are not inherently indicative of a genetic defect, despite common misconception. Instead, haplotypes serve as a tool for identifying specific defects, especially when the causal variant is unknown or when a direct gene test is not yet available. ❕ Haplotype tests are not done in the laboratory, but instead at the evaluation center ❕ Haplotype tests are estimates and statuses are thereby subject to change. This can happen when data gets updated and/or genotypes get re-imputed To communicate efficiently it's important to differentiate between haplotypes, recessive traits, and gene tests. By familiarizing ourselves with the correct definitions we can avoid misunderstandings and instead correctly manage genetic conditions. Check out the below article for more information #haplotypes #knowledgeispower #genetics

Learn how disease impacts calves and explore the heritability ranges for respiratory disease and diarrhea. 📊 Find out why accurate data recording is crucial for effective genetic selection. . . . . . . . . . . . #DairyResearch #CalfDiseases #GeneticParameters https://ow.ly/qpXA50QwwMC

🚨I hope you didn't forget our preprint about the use of RenSeq to uncover canola NLRome (still under review): https://lnkd.in/eUJyp5eQ 🎧 If you need a refresh, listen to this amazing podcast created by Google Notebook! This will change how we share science: https://lnkd.in/e8m793wE

Never heard of Metformin?     Thomas Szucs is an expert in that field and explains the importance of #telomeres in our #podcast «The Longevity Code». In the discussion with Anna Erat (MD, PhD, IDP INSEAD) they talk about how #longevity can be achieved within the molecules of our body.   But what do those words mean exactly?   Here is a quick guide:   ►Metformin: #Metformin is a well researched molecule used in type 2 diabetes. It is also a drug hyped by some in the longevity field. The podcast sheds more light on Metformin and healthy aging.   ► Telomeres: #Telomeres are the specific DNA-protein structures that are found on both ends of chromosomes. They protect the genome from nucleolytic degradation, unnecessary recombination, repair, and intrachromosomal fusion.   ► Telomere shortening: With each round of cell division, telomeres shrink. Because a telomere can only shrink to a certain degree, it is deeply intertwined with our longevity.   Today’s research is still ongoing but with enough patience, the results could be astonishing.   Where do you see further #potential in today’s research regarding telomeres?   👉 Listen to this episode as we talk about the possibility of a prolonged lifespan with deep insights from a leading #expert in the field! You can find the links to the episode below.   Comment: ► Listen to the podcast on Spotify here: https://lnkd.in/ehW32h6G   ► Listen to the podcast on Apple Podcast here: https://lnkd.in/eFdeWit9   ► Listen to the podcast on YouTube here: https://lnkd.in/eSQucbdC

Didn't catch our latest Patient Empowerment Program podcast episode? It's still warm for you. https://lnkd.in/gp2s448H   Mutations affecting ion channels are the most common cause of 'applications for treatment' submitted to n-Lorem. These channels regulate the passage of essential electrically charged ions, like sodium, potassium, calcium, and chloride, into cells. Alas, ion channels pose a significant challenge in the ASO discovery process, as there is little room for error due to the need for highly allele-selective ASOs to achieve success. Let’s 'dive into the channel' and explore the complexities of treating patients with ion channel mutations. 

Nature versus nurture!     In the third episode of our podcast "The Longevity Code", we explore the role and interplay of nature and nurture when it comes to longevity and chronic disease with Thomas Szucs, Professor of Pharmaceutical Medicine.   According to Thomas Szucs, this is the question of questions, and he uses a metaphor to illustrate his point:   ► Loading a gun with ammunition is the sum of your genes   ► Pulling the trigger is your lifestyle   Thomas Szucs has years of experience in both academia and industry, making him a leading authority on health economics, policy and management.   His research focuses on the impact of genetic predisposition and how lifestyle choices can influence our health outcomes.   👉 Listen to this episode as we unravel the mysteries of our genes and lifestyle with deep insights from a leading expert in the field! You can find the Links to the current episode as a comment in the attachment.   #longevity #thelongevitycode #podcast

In an age where researchers are looking for viable alternatives to working with animals, Dr. Thomas Hartung is intrigued by organoids, which carry the intelligence needed to offer rapid insights into disease progression and treatment. Join us as we explore their creation, functionality, and more in the first chapter of Vital Science’s limited series, Bold New Approaches. https://okt.to/1GVzjd #VitalScience #Podcast

✅️Gene Mutations Can Affect Glutathione Production 👉Glutathione helps protect cells from damage and if you’re deficient, it can cause a slew of problems, from fatigue and depression to type 2 diabetes and Alzheimer’s. Nayan Patel PharmD 🎧 Listen or watch the full Metabolic Freedom Podcast episode with Dr. Nayan Patel. A Ben Azadi Production | MFP Ep #795 (link in bio)

The latest episode of the Preparing for a Cell and Gene Future podcast series addresses a rising trend in the adoption of accelerated regulatory pathways for fast tracking promising novel medicines through clinical development. Parexel experts Jamie Pierson and Kim MacDonnell discuss the criticality of accelerated development in rare diseases, promising signals from the FDA and stakeholder engagement strategies to ensure broader access to new treatments. Listen here: https://lnkd.in/gdGQhfyv