Didn't catch our latest Patient Empowerment Program podcast episode? It's still warm for you. https://lnkd.in/gp2s448H Mutations affecting ion channels are the most common cause of 'applications for treatment' submitted to n-Lorem. These channels regulate the passage of essential electrically charged ions, like sodium, potassium, calcium, and chloride, into cells. Alas, ion channels pose a significant challenge in the ASO discovery process, as there is little room for error due to the need for highly allele-selective ASOs to achieve success. Let’s 'dive into the channel' and explore the complexities of treating patients with ion channel mutations.
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Learn all about positive ANA and what that means! In this fascinating episode of the UnabridgedMD Podcast, Dr. Amigues explains a positive ANA (antinuclear antibody) test means and its significance in diagnosing autoimmune disorders. Listen to the full episode here: https://lnkd.in/gyeX-HEe #positiveANA #antinuclearantibody #autoimmunedisorder #immunesystem #antibodies #inflammation #autoantibodies #titers #typesofANA #additionaltesting #infections #medications
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Luxatio Erecta is the specific term for inferior dislocation of the glenohumeral joint trapped underneath the coracoid and glenoid, very commonly associated with neurovascular injury. The pathogenesis is typically from a high-energy injury from a hyperabduction force applied to the arm, levering the proximal humerus onto the acromion, injuring inferior capsule/labrum, which subsequently allows for disengagement of HH inferiorly from glenoid, and it commonly involves variable sized tearing of static glenohumeral ligaments. Diagnosis is made clinically with the presence of the shoulder in a fixed, abducted position and confirmed with radiographs of the shoulder. Treatment is closed reduction and assessment of possible concomitant neurovascular injury. Learn more high-yield concepts about Luxatio Erecta on our DAILY Orthobullets podcast. Listen wherever you listen to podcasts! https://bit.ly/3vp1v3K
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Periosteal Chondromas are rare, benign, chondrogenic tumors that occur on the surface of long bones, most commonly the proximal humerus. Patients typically present between the ages of 10 and 20 years of age with regional pain secondary to irritation of overlying tendons. Diagnosis is made with radiographs showing a well-demarcated, shallow cortical defect with saucerization of the underlying bone. Treatment is usually observation. Marginal surgical excision of the lesion, including the underlying cortex, is indicated in patients with severe and progressive pain. Learn more high-yield concepts about Periosteal Chondromas on our DAILY Orthobullets podcast. Listen wherever you listen to podcasts! https://bit.ly/49RGZHB
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Listen to the podcast of "Effectiveness of endoscopic resection for colorectal neoplasms in ulcerative colitis: a multicenter registration study" by Hirai and colleagues. https://lnkd.in/gDCD_cD
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Fanconi Syndrome is a type of renal tubular acidosis (type 2) in the proximal convoluted tubules (PCT). Patients typically present with polyuria/polydipsia, bone pain and pathological fractures, myalgias and weight loss, and failure to thrive or developmental delay. On physical exam they show signs of rickets such as bowed legs, scoliosis, or teeth abnormalities. Treatment is supportive care with fluid/electrolyte repletion and vitamin D if osteomalacia is present and bicarbonate supplementation for metabolic acidosis. Learn more high yield-concepts about Fanconi Syndrome on our DAILY Medbullets Step 2 & 3 podcast. Listen wherever you listen to podcasts! https://bit.ly/3QYThaf
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Dunbar Ivy, MD discusses the value of repeat heart catheterization in patients with pulmonary hypertension and why cardiac MRI can be used as an alternative to heart caths in certain cases. phaware® podcast ep 480. Like, Subscribe and Follow. Scan QR Code to LISTEN NOW. #phaware #pulmonaryhypertension #podcast #pulmonary #lungs #pah @pphnet
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Osteoblastomas are benign, aggressive osteogenic bone lesions commonly found in the posterior elements of the spine. Patients typically present between ages 10 and 30 with regional pain with only partial response from NSAIDs. Diagnosis is made radiographically by a characteristic lesion that is > 2 cm in diameter with a sclerotic margin and radiolucent nidus. Treatment is usually curettage or marginal excision with bone grafting. Learn more high-yield concepts about Osteoblastomas on our DAILY Orthobullets podcast. Listen wherever you listen to podcasts! https://bit.ly/3OEitRI
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