Nanion Technologies’ Post

Did you know that over 1,300 human disorders have now been linked to mutations in ion channel genes? These channelopathies are crucial to disease mechanisms, opening new frontiers for drug discovery. In his latest blog, Marc Rogers explores how genetic screening is identifying more of these mutations, and how automated patch clamp (APC) technology is driving breakthroughs. This high-throughput technology enables rapid, precise characterization of ion channels, a key step toward developing effective, targeted therapies. Want to understand how this technology is accelerating precision medicine? Check out the blog for insights on: ◾ Case studies on cardiac and neuronal ion channels ◾ Comparisons of APC with methods like in silico modeling ◾ How APC is translating genetic discoveries into real-world clinical success Don't miss this chance to explore the latest channelopathy research insights! Read the full blog here: https://ow.ly/fcrs50TLt9B #Channelopathies #IonChannels #DrugDiscovery #GeneticScreening #APC #PrecisionMedicine

𝐀𝐝𝐯𝐚𝐧𝐜𝐞𝐬 𝐢𝐧 𝐋𝐢𝐪𝐮𝐢𝐝 𝐁𝐢𝐨𝐩𝐬𝐲 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐟𝐨𝐫 𝐃𝐢𝐬𝐞𝐚𝐬𝐞 𝐃𝐞𝐭𝐞𝐜𝐭𝐢𝐨𝐧, 𝐃𝐢𝐚𝐠𝐧𝐨𝐬𝐢𝐬, 𝐚𝐧𝐝 𝐓𝐫𝐞𝐚𝐭𝐦𝐞𝐧𝐭 𝐚𝐧𝐝 𝐖𝐡𝐚𝐭 𝐭𝐡𝐞 𝐅𝐮𝐭𝐮𝐫𝐞 𝐌𝐚𝐲 𝐇𝐨𝐥𝐝 𝐋𝐢𝐪𝐮𝐢𝐝 𝐛𝐢𝐨𝐩𝐬𝐲 is transforming the landscape of disease diagnostics! Compared to traditional biopsies, this minimally invasive method offers a simple blood draw to detect circulating #cancercells and genetic mutations. The ability to capture comprehensive data from across the body, combined with rapid results, allows for quicker, more precise treatment decisions. Advances in 𝐧𝐞𝐱𝐭-𝐠𝐞𝐧𝐞𝐫𝐚𝐭𝐢𝐨𝐧 𝐬𝐞𝐪𝐮𝐞𝐧𝐜𝐢𝐧𝐠 (𝐍𝐆𝐒) and multi-analyte approaches are significantly enhancing the sensitivity and accuracy of 𝐥𝐢𝐪𝐮𝐢𝐝 𝐛𝐢𝐨𝐩𝐬𝐢𝐞𝐬. Technologies like CancerSEEK and OneTest are pushing the boundaries, enabling early detection of various #cancers. Discover more about the cutting-edge research and future possibilities of liquid biopsies with Courtney Noah, PhD 🔗𝐋𝐞𝐚𝐫𝐧 𝐌𝐨𝐫𝐞: https://lnkd.in/gt42HtU6 #LiquidBiopsy #DiseaseDetection #CancerResearch #HealthcareInnovation #MedicalTechnology #NGS #EarlyDetection #PrecisionMedicine #Biotech #Genomics #AIinHealthcare #NeurodegenerativeDiseases #FutureOfHealthcare #MedicalResearch #ClinicalTrials

Nanocarriers: The Tiny Couriers Revolutionizing Medicine! 🚀 Did you know that nanocarriers can deliver life-saving treatments directly to the cells that need them most? Instead of medicine traveling blindly through the body, these microscopic messengers guide drugs straight to their target—whether it’s a cancer cell or an infection—leaving healthy cells untouched! 🎯 It’s like sending a special delivery package, equipped with a secret key to unlock the right door. Once the medicine is delivered, the nanocarrier is safely broken down, leaving your body treated and ready to heal. 🛡️ Why are nanocarriers a game-changer? They minimize side effects, boost drug effectiveness, and can even bypass barriers like the blood-brain barrier that traditional treatments can’t reach. 🧬 From targeting cancer to fighting infections, nanocarriers are transforming the future of medicine, and the possibilities are limitless. Researchers are already exploring how they can tackle antibiotic resistance, deliver gene therapies, and more! 🌟 To dive deeper into this cutting-edge technology, check out the full article through the link below! 💊✨ https://lnkd.in/dBAde_5Z #biology #biotech #biotechnology #molecularbiology #genetics #science #medicine #nanocarriers #drugdelivery #nano #nanotechnology #bio #bioengineering #cell #medical #medicalinnovation #futureofmedicine #nanomedicine #biologyto

We are excited to share some of the activities from our Pathfinder Challenge #IMPACT, which aims to revolutionize how we understand and treat Arrhythmogenic Cardiomyopathy (ACM). 🧬❤️ 🔍 We aim to use AI to integrate clinical and genomics data from ACM patients to uncover the secrets ACM and pinpoint actionable therapeutic targets. 🌐 Our approach entails: ✅ Patient Data Analysis in order to explore gene variants, and identify potential drug targets. ✅ Innovative Techniques: employing single nucleus RNA sequencing, in situ capturing, small RNA sequencing, and proteomics on deeply phenotyped patients to correlate findings and identify drug targets. ✅ Utilizing unsupervised algorithms and models to discover patient clusters with common traits, predict disease risk, and validate our findings. This integration of clinical information and -omics data through advanced AI and HPC technologies paves the way for personalized treatment strategies. 🌟 Stay tuned as we continue to push the boundaries of ACM research and work towards improving patient outcomes. 💡🔬 Be a part of our journey and follow us! Stay tuned and visit https://lnkd.in/dZv23Xku for more! #ACM #IMPACT #Cardiogenomics

Germany’s biotech industry on the rise: The latest report by EY and BIO Deutschland e. V. highlights a promising first half of 2024, with venture investments in German biotech reaching €494 million—already 93% of last year’s total. Explore the German Biotechnology Report 2024 here: https://lnkd.in/e8AH7WtH A new aging atlas from Howard Hughes Medical Institute (HHMI)’s Janelia Research Campus offers a detailed look at how cells and tissues in worms age. This comprehensive atlas maps gene expression changes, providing insights that could pave the way for innovative anti-aging treatments: https://lnkd.in/errCRzHc New research at the University of Wisconsin-Madison outlines how protein restriction in a mouse model of Alzheimer’s slows disease pathology, promotes metabolic health, and extends lifespan. The study observed significant benefits, particularly in female mice, demonstrating reduced disease markers and enhanced cognitive performance, potentially offering a new dietary intervention approach to combat Alzheimer’s: https://lnkd.in/eedZKrWu #ICYDK #ApolloVC #Lifespan #Healthspan #Longevity #VentureCapital

𝐅𝐫𝐨𝐦 𝐆𝐞𝐧𝐞𝐬 𝐭𝐨 𝐌𝐨𝐥𝐞𝐜𝐮𝐥𝐞𝐬: 𝐓𝐡𝐞 𝐅𝐮𝐭𝐮𝐫𝐞 𝐨𝐟 𝐌𝐞𝐝𝐢𝐜𝐢𝐧𝐞 𝐌𝐮𝐥𝐭𝐢-𝐨𝐦𝐢𝐜𝐬, the simultaneous analysis of multiple biological data types (e.g., genomics, transcriptomics, proteomics, metabolomics), is significantly enhancing our understanding of complex biological systems. By integrating these diverse datasets, researchers are: 𝐈𝐝𝐞𝐧𝐭𝐢𝐟𝐲𝐢𝐧𝐠 𝐧𝐨𝐯𝐞𝐥 𝐛𝐢𝐨𝐦𝐚𝐫𝐤𝐞𝐫𝐬: Pinpointing specific molecular markers that can predict disease risk, aid in early diagnosis, and monitor treatment response. For example, multi-omics studies have identified new biomarkers for cancer, neurodegenerative diseases, and cardiovascular disorders. 𝐃𝐢𝐬𝐜𝐨𝐯𝐞𝐫𝐢𝐧𝐠 𝐧𝐞𝐰 𝐝𝐫𝐮𝐠 𝐭𝐚𝐫𝐠𝐞𝐭𝐬: Uncovering previously unknown biological pathways involved in disease, leading to the development of more effective and targeted therapies. By analyzing the interactions between genes, proteins, and metabolites, researchers can identify novel therapeutic targets that were previously overlooked. 𝐔𝐧𝐝𝐞𝐫𝐬𝐭𝐚𝐧𝐝𝐢𝐧𝐠 𝐝𝐢𝐬𝐞𝐚𝐬𝐞 𝐦𝐞𝐜𝐡𝐚𝐧𝐢𝐬𝐦𝐬: Gaining a deeper understanding of how genetic, transcriptional, protein, and metabolic changes contribute to the development and progression of diseases. Multi-omics studies have provided insights into the complex interplay of factors involved in various diseases. Multi-omics has the potential to transform healthcare by enabling personalized medicine, improving disease prevention, and accelerating drug discovery. Join the conversation and learn more about the exciting advancements in this field! #multiomics #healthcare #medicalresearch #medicine #clinicalresearch #biotechnology #innovation #translationalmedicine #translationalresearch

Future of JMML Treatment is Bright Advancements in precision medicine and genomic technologies are transforming JMML care. By understanding the genetic and molecular underpinnings of this disease, researchers are developing more effective, targeted therapies for children. #CancerCare #PrecisionOncology #FutureOfMedicine #JMMLHope

A Complete Guide of 𝐌𝐨𝐥𝐞𝐜𝐮𝐥𝐚𝐫 𝐃𝐢𝐚𝐠𝐧𝐨𝐬𝐭𝐢𝐜𝐬 - [PDF Guide] ➡ 𝐂𝐥𝐢𝐜𝐤 𝐡𝐞𝐫𝐞 𝐟𝐨𝐫 𝐏𝐃𝐅>> https://lnkd.in/dbyTkMFB Molecular #diagnosis helps to analyze the #DNA or #RNA sequences for the potential emergence of specific #diseases. These tests determine whether a patient has gene mutations associated with a specific disease. The growth of this market is driven by the technological advancements in molecular diagnostics, the increasing use of #PoC diagnostic tests, an increase in funding for the R&D of diagnostic products, the rising geriatric population, and the increasing prevalence of target diseases. However, unfavorable regulatory framework and cost of molecular diagnostic tests hamper the growth of this market to a notable extent. 𝐃𝐫𝐢𝐯𝐞𝐫𝐬 ·      Rising Global Geriatric Population ·      Rising Prevalence of Communicable and Non-communicable Diseases ·      Technological Advancements in Molecular Diagnostics ·      Rising Healthcare Expenditure 𝐛𝐲 𝐓𝐞𝐜𝐡𝐧𝐨𝐥𝐨𝐠𝐲 ·      Polymerase Chain Reaction (PCR) ·      In Situ Hybridization (ISH) ·      Isothermal Nucleic Acid Amplification Technology (INAAT) ·      Microarrays ·      Mass Spectrometry ·      Sequencing ·      Other Technologies #MolecularDiagnostics #GenomicTesting #PCR #NextGenSequencing #NGS #DNASequencing #RNASequencing #MolecularBiology #PrecisionMedicine #PersonalizedMedicine #Biomarkers #GeneticTesting #InfectiousDiseaseDiagnostics #CancerDiagnostics #healthcare

📢 #EPUAP2024 abstracts included in a special edition of the Journal of Wound Care (JWC)! This special #EPUAP issue of JWC will include these key highlights: 🧬 The role of biomarkers in predicting pressure and diabetic foot ulcers. 📊 The use of epidemiological data to enhance pressure ulcer/injury management strategies. 🛏️ Evaluation of air-filled mattresses in #neonatal PU prevention. 🔬 A randomized trial exploring autologous whole blood clot for #diabetic foot ulcer healing. 🧪 A study on continuous topical oxygen therapy and its impact on biofilm gene expression. Would you like to know more? Attend the EPUAP 2024 Annual Meeting starting in less than a week in Lausanne, Switzerland! 👉 https://lnkd.in/e6ciDMEh Find the full issue here 👉 bit.ly/JWC_EPUAP24 #EPUAP #WoundCare #PressureUlcers #HealthcareInnovation #JWC #WoundHealing #StopThePressure

#Molecularmedicine is important for a couple of reasons: It revolutionizes our understanding of diseases (#FutureofMedicine) and allows for the development of more #targetedtreatments (#PrecisionMedicine). Traditionally, medicine focused on symptoms and affected organs. Molecular medicine dives deeper, examining the underlying causes of diseases on a molecular level. This can include things like genetic mutations or malfunctioning proteins. By understanding these mechanisms, researchers can develop more precise treatments aimed at the root cause of the illness, rather than just managing symptoms. This approach has led to significant advancements in various areas. For instance, it has enabled the creation of personalized medicine, where treatments are tailored to an individual's specific genetic makeup (#Genomics #PersonalizedHealthcare). It also plays a crucial role in developing new drugs and gene therapies for diseases that were previously untreatable (#DrugDiscovery #GeneTherapy). Overall, molecular medicine holds immense potential for improving diagnosis, treatment, and prevention of a wide range of diseases. (#HealthcareInnovation #TheFutureisNow)