Nanolive SA’s Post

Check Molecular Devices Clone Screening much-anticipated demo with SEED Biosciences on the DispenCell Single-Cell Dispenser and CloneSelect Imager. Discover how they‘re transforming the landscape of cell isolation and monoclonality verification. Learn about their unparalleled precision, efficiency, and how they can elevate your research. 🎥 Watch the recorded demo and see firsthand the innovation that’s setting new standards in cell analysis. 👇 👇 https://lnkd.in/dt5Bh-uP #biotech #singlecellanalysis #singlecell #cellbiology #celllinedevelopment #biopharma #monoclonality

Curious about the future use of blood microsampling in decentralized clinical trials to support the development of antisense oligonucleotides therapies? Find out how our scientists achieved precision, accuracy, and linearity within acceptance criteria using our sensitive and selective bioanalytical method for determining ASOs. https://lnkd.in/dyK3vUzz #Bioanalysis #MassSpectrometry #Microsampling

📍 APP NOTE | Blood-Brain Barrier (BBB) Antibody Penetration Assay on Gri3D®. 🧑🏻🔬 Multiple models of #BBB have been established using transwell inserts or microfluidic devices. While these systems recapitulate key properties of the #BBB, they come with limitations in terms of scale, ease of use and analysis. With #Gri3D, we were able to #ScaleUp the generation of highly reproducible #BBB organoids from endothelial cells, pericytes and astrocytes. With more than #5000 datapoints in a single 96 well plate, the model was used for antibody penetration assay in #HighThroughput 📊. 👁️ Interested? Do you want to know more? Read our #ApplicatonNote here: https://lnkd.in/dsJGWm9 and drop us a message 📬! #3Dcellculture #organoids #biotechnology #research #personalizedmedicine #invitromodel #BBB

Check Molecular Devices Clone Screening much-anticipated demo with SEED Biosciences on the DispenCell Single-Cell Dispenser and CloneSelect Imager. Discover how they‘re transforming the landscape of cell isolation and monoclonality verification. Learn about their unparalleled precision, efficiency, and how they can elevate your research. 🎥 Watch the recorded demo and see firsthand the innovation that’s setting new standards in cell analysis. 👇 👇 https://lnkd.in/dt5Bh-uP #biotech #singlecellanalysis #singlecell #cellbiology #celllinedevelopment #biopharma #monoclonality

🚀 Exciting News: Introducing a new high-performance lyophilized product from New England Biolabs LyoSciences supporting molecular diagnostic developers! 🧬   Join us in revolutionizing nucleic acid amplification with our latest innovation: LyoPrime WarmStart Fluorescent LAMP/RT-LAMP Mix (with UDG)! https://lnkd.in/edcDg72A   Key Features: 🌿 Lyophilized format for ambient shipping and storage 🧬 One-step solution for Loop-Mediated Isothermal Amplification of DNA and RNA targets ⛔️ Thermolabile UDG and dUTP included to reduce carryover contamination 🌈 Includes fluorescent dye for real-time fluorescence measurement 🔥 WarmStart technology inhibits enzyme activity at room temperature   Whether you're in research, diagnostics, or biotech, our LyoPrime WarmStart fLAMP Mix offers unparalleled convenience and reliability. With a shelf life of 2 years at room temperature, you can trust in its performance whenever you need it.   Join the webinar on Lyophilizing Reagents to learn more about this groundbreaking technology and our expertise: https://lnkd.in/eTn4ZcEw   Let's amplify progress together! 💡 #NEB #NEBLS #Lyo #Lyophilisation #molecularbiology #DNA #RNA #diagnostics #biotech #LAMP

💻 Have you registered for our upcoming webinar with Bruker? 📅 29 November at 15:00 GMT 💭 Learn about the biophysical characterisation of binary and ternary drug-target complexes Key takeaways include: 💭 Support of Hit ID and Hit characterisation in early drug discovery by biophysical methods 💭 Case studies on assay development for binary and ternary complex formation assays 💭 SIERRA SPR-32 PRO Platform applications to obtain insights on binding affinities and binding kinetics for small (NCE) and large (NBE) binders 💭 SPR method development to support kinetic characterisation of recalcitrant drug targets directly from cellular extracts. You'll be able to ask questions of our speakers Daniel Schwarz from Merck Healthcare and Pedro Sousa from iBET - Instituto de Biologia Experimental e Tecnológica too. Register through the link in the comments 👇 #Webinar #DrugDiscovery

If L-glutamine is not added to the cell culture media, several adverse effects can occur: 1.Reduced Cell Growth and Viability: Cells may exhibit significantly slower growth rates or fail to proliferate effectively due to insufficient energy and building blocks for macromolecule synthesis. 2.Metabolic Stress: Lack of L-glutamine can lead to metabolic stress, as cells struggle to meet their energy and biosynthetic demands, potentially leading to cell death or apoptosis. 3.Altered Cellular Functions: Essential cellular functions dependent on proteins and nucleotides might be impaired, affecting cell signaling, maintenance, and overall functionality. 4.Unstable pH: The culture medium's pH may become less stable, potentially creating an inhospitable environment for cell growth and survival. In summary, L-glutamine is indispensable in mammalian cell culture media for maintaining cellular energy, growth, viability, and proper metabolic functions. Without it, cell cultures would likely suffer from poor growth, reduced viability, and increased susceptibility to metabolic stress. #aminoacid #biotech #research #upstream #bioprocess #biopharma #mammaliancellculture #cellculture

Explore the link between histone deacetylases and #epigenetic modifications with our peer reviewed HDAC1 recombinant #antibody. Tested for WB, IHC-P, IF + IP with human, mouse and rat reactivity View info here: https://hubs.li/Q02gCBRD0 #phdlife #research #biotech #cancerresearch

🔬With just 3 days to go until  #GermanPeptideSymposium2023, the excitement is buzzing at Gyros Protein Technologies! Our team is busy preparing to showcase the power of #PurePep solutions in Jena, Germany. We're bringing speed, sustainability, and reliability to peptide synthesis and purification - it's time to redefine the future of biomedical research. At Gyros Protein Technologies, we understand the need for speed without sacrificing quality. Our peptide synthesizers and purification technologies can help you take your R&D to the next level and unlock the potential for new therapeutic discoveries. 💡Remember to visit us for interactive and informative sessions. 📅On Tuesday August 29, Robert Zitterbart will give a short talk at 4.40pm. See first-hand how our #PurePep solutions can accelerate your molecular journey. Our team of experts is ready to engage, discuss, and define new opportunities for peptide innovation. We look forward to seeing you soon, and let's make this year's  #GermanPeptideSymposium2023 a remarkable milestone on the path to the next medical breakthrough! The countdown to innovation begins now!⏳ https://lnkd.in/dJA57q6Y #peptides #synthesis #purification #purepep

🔬 Rely On Our 20+ Years Of #LCMS Expertise For Your #Oligonucleotides—ASOs, SiRNAs, Aptamers, MiRNA, And Beyond. We’re Trusted Partners Of #Biotech, Pioneering Treatments For The #Undruggable.🧬 🚀 Swift LC-MS Method Development For #DrugDiscovery To #GLP Studies 🔍 Unmatched #Selectivity, With Low LLOQ In Tissues And Fluids 📈 Advanced Sample Prep For High #Specificity And #ExtractionRecovery 🎯 Consistent Assay Reproducibility For #PK And #Biodistribution Data 👨🔬 Trust Our Mass Spec And Hybrid ELISA Experts To Propel Your Oligonucleotide Methods. Speak To Our Scientists And Explore Case Studies Demonstrating Our Hand-On Experience With Oligos. https://lnkd.in/dw2ra3KM