Neurologi DK’s Post

The Alzheimer's Disease International 'From Plan to Impact VII' report has just been launched. Wyllians Vendramini Borelli, MD, PhD and Eduardo Zimmer contributed with an essay describing how dementia state plans can help in collecting massive amounts of biomarker and clinical data in collaboration with SUS Ministério da Saúde in Brazil 🇧🇷 Read the full report here 🔗 https://lnkd.in/eabgzyz6

Coya is leveraging the potential of Tregs in #neurodegenerative diseases and expanding its pipeline for COYA 302 beyond ALS to include frontotemporal dementia (FTD) and Parkinson’s disease (PD). Our updated pipeline can be viewed here: https://lnkd.in/gcumdV2G #ALSawareness #BiotechInnovators #Biotech #Science

The pathological hallmarks of fibrillary amyloid-beta and tau tangles are similar between early-onset Alzheimer's disease (EOAD) and late-onset Alzheimer's disease (LOAD), but many other pathological characteristics differ between the two. For instance, the medial temporal lobe (MTL) has previously been described as being spared in EOAD compared to LOAD. However, the classification of EOAD is based solely on age of onset, and it is known that clinical differences exist within EOAD. Laura Wisse and her team have explored how the MTL is affected in amnestic (memory-impaired) EOAD and compared it to amnestic LOAD, finding evidence of MTL atrophy in amnestic EOAD. Lead author: Anika Wuestefeld Link to article: https://lnkd.in/dvBzgfxF #MedialTemporalLobe #Alzheimers #EOAD #LOAD #amnesticEOAD #atrophy

It is such an honor to contribute to the most important Report in Alzheimer's disease globally with Dr Eduardo Zimmer. Check Chapter 7 to read our piece on the potential of game-changing strategies that the Brazilian Public Health System has.

🤲 To mark World Alzheimer's Day, we reaffirm our commitment to the fight against neurodegenerative diseases. Early detection and accurate diagnosis are crucial for effective management of these conditions. Our advanced quantitative brain MRI solution, VUNO Med-DeepBrain, provides invaluable insights by analyzing subtle changes in brain volume and white matter hyperintensity (WMH) burden. By leveraging this technology, healthcare professionals can be supported in detecting the early signs of neurodegenerative diseases and identifying patients who may be suitable for anti-amyloid therapy. We believe that technology can be a powerful ally in the battle against Alzheimer's. Together, let's work to enhance early detection, support groundbreaking research, and improve the quality of life for those affected by this challenging disease. 👊 Join us in raising awareness and advocating for innovation in the diagnosis and treatment of Alzheimer's. #WorldAlzheimersDay #AlzheimersAwareness #NeurodegenerativeDiseases #EarlyDetection #HealthcareInnovation #BrainHealth #MedicalTechnology #MedicalAI #VUNO

The earliest possible diagnosis and active prevention measures are important pillars in countering the rising number of Alzheimer's cases. However, a lot of valuable time usually passes before the correct diagnosis is made and the procedures are complex and expensive.   A new, simple blood test based on the detection of the phosphorylated tau protein at threonine 217 (P-tau217) in blood plasma has demonstrated an impressive diagnostic accuracy of 90 percent in studies. The new test, developed under the leadership of Lund University, Sweden, could significantly expand the possibilities of early Alzheimer's detection thanks to the use of this biomarker and could also be used in primary care in the future:   https://lnkd.in/dq6X9Qi9   #alzheimers #alzheimersresearch #alzheimersdiagnosis #alzheimersearlydetection #dementia #dementiaearlydetection #alzheimersbloodtest #alzheimerstauprotein #alzheimersbiomarker #ptau217#universitylund  

🚀 Exciting Breakthrough in Alzheimer's Research! Alzheimer's disease, the leading cause of dementia, has long challenged the medical community due to limited treatment options with considerable risks and side effects. But hope is on the horizon! Recent studies reveal that sodium-glucose cotransporter 2 inhibitors (SGLT-2i) could offer neuroprotective benefits. This comprehensive review highlights the intricate mechanisms of SGLT-2i in combating AD, including antioxidative stress, anti-neuroinflammation, improved autophagy, and endothelial protection. As research progresses, SGLT-2i is emerging as a promising candidate for Alzheimer's treatment. Let's look forward to a future where we can better combat this challenging disease and improve patient outcomes! 🌟 Read Research 👉🏻 https://lnkd.in/dvXA69my #research #pubmed

Check out this fascinating interactive timeline by Nature that explores the history of #Alzheimer's #disease. From its discovery over a century ago by Dr. Alois Alzheimer to the cutting-edge research happening today, this timeline highlights the major milestones in our understanding of the disease. As Alzheimer's continues to impact millions of people worldwide, advancements in diagnostics, treatments, and prevention are more critical than ever. This resource provides an insightful journey through the scientific breakthroughs and challenges faced in the battle against this complex neurodegenerative disease. Whether you're in the healthcare field, a caregiver, or just interested in the subject, this timeline offers a comprehensive view of how far we've come—and how far we still have to go. Explore the timeline here: Nature - History of Alzheimer's Disease (https://lnkd.in/gsWSn328)

A new frontier in neurodegenerative disease treatment: a recent study published in #APNexus introduces a noninvasive photonic approach using near-infrared light. 💡 This innovative method holds great promise for the future of #photomedicine, potentially offering a noninvasive, cost-effective treatment for millions of individuals suffering from diseases such as Parkinson's, Alzheimer's, and ALS: https://lnkd.in/gyB8YCXu

If confirmed, this study will be amongst the top cited papers in the field of neurodegenerative pathologies in the years to come. Evidence that Alzheimer could be be transmitted by prions!? https://lnkd.in/eEADr4c7