The only way we can overcome low awareness of #sicklecelldisease and the stigmas faced by people living with it is by starting more conversations. This #WorldSickleCellDay we’re asking you to join us in raising awareness. Have one conversation with one other person about Sickle Cell Disease today. You can learn more about it here: https://lnkd.in/dM-YdTN We are committed to a future where it is possible to #liveunlimited with sickle cell disease, are you? #WorldSickleCellDay #WSCD2024
CRISPR - discovered in the 1980s, and first demonstration of technology used in CRISPR-based genome editing ready app. a decade ago - had its first FDA approved treatment for sickle cell disease December last year: https://www.fda.gov/news-events/press-announcements/fda-approves-first-gene-therapies-treat-patients-sickle-cell-disease The fact that this is a historical milestone for the CRISPR technology will make sickle cell disease something we will never forget... even when it is CRISPR edited away...
Preventing sickle cell disease isn't just a goal; it's a moral imperative. Every child deserves a chance at a healthy life, free from the pain of sickle cell disease. Prevention is better than cure, especially when it comes to sickle cell disease. Let's invest in research, screening, and Public health initiatives to stop SCD in its tracks.
Sickle cell disease is a group of inherited red blood cell disorders. In SCD, the red blood cells become hard and sticky and look like a C-Shaped farm tool called a "Sickle".
Incredible contribution from Novo Nordisk to engage people to know, learn and teach more about #sicklecelldisease. Join #WorldSickleCellDay!!
General Manager,Nagoya International(Shanghai) Co. Ltd
1moPatients with sickle cell disease suffer from unpredictable and painful events when sickled red blood cells block blood flow to the point depriving tissues of oxygen. The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophils. More research needed on Pyruvate Kinase . PKM2 also regulates the rate-limiting step of glycolysis that shifts the glucose metabolism from the normal respiratory chain to lactate production in tumor cells. Besides its role as a metabolic regulator, it also acts as protein kinase, which contributes to tumorigenesis. PKM2 is a potential diagnostic marker and as a therapeutic target in cancer treatment also. .