Odimma Therapeutics’ Post

Thank You Labiotech.eu for hosting this podcast. In this almost 30 min I had the opportunity to talk about the exciting clinical development of ISTH0036 - a TGF-beta 2 targeting antisense. This is the lead compound of Isarna Therapeutics GmbH, currently in Phase 2 trials for wet AMD and DME (with positive data just presented at @OIS and @ARVO by our CMO, Prof. Marion Munk, M.D., Ph.D ...). I also discuss briefly the promising antisense technology and its use as clinical therapy in general. Check it out!

Can you make sense of antisense therapies? 🧐 Antisense therapies are single-stranded synthetic RNA or DNA molecules that bind to complementary nucleic acid sequences to modulate protein expression. 🧬 Isarna Therapeutics GmbH is developing a portfolio of antisense therapies to treat eye diseases. 👁️ Labiotech was in conversation with Rene Rückert, M.D. MBA, COO of Isarna Therapeutics, who discussed the potential role of these drugs in tackling diseases. 🎧 Tune into the latest episode of the Beyond Biotech Podcast to know more about this novel technology! 👇 https://lnkd.in/dhUnhhgH #BeyondBiotechPodcast #antisensetherapies #RNA #DNA #proteinexpression #eyediseases #biotechinnovation 

Today is #RNADay! #RNA is vital for transmitting genetic information, regulating genes, and enabling protein synthesis. At Elixirgen Therapeutics, we're reimagining the power of RNA by developing life-changing therapies for patients in need. Learn more: https://bit.ly/4euOyXI

𝗙𝗥𝗘𝗘 𝗚𝗨𝗜𝗗𝗘: 𝗘𝘅𝘁𝗿𝗮𝗰𝘁𝗶𝗼𝗻 𝗼𝗳 𝗢𝗹𝗶𝗴𝗼 𝗧𝗵𝗲𝗿𝗮𝗽𝗲𝘂𝘁𝗶𝗰𝘀 𝗳𝗿𝗼𝗺 𝗕𝗶𝗼𝗹𝗼𝗴𝗶𝗰𝗮𝗹 𝗦𝗮𝗺𝗽𝗹𝗲𝘀 𝗙𝗼𝗿 𝗟𝗖-𝗠𝗦 𝗕𝗶𝗼𝗮𝗻𝗮𝗹𝘆𝘀𝗶𝘀 Unlock the power of Clarity OTX solid phase extraction (SPE) and buffer products to isolate RNA and DNA-based therapeutics and metabolites from biological fluids and tissues in record time! Learn more in our guide: https://lnkd.in/g8HWjxzT

Extracellular vesicles (EVs) are garnering immense interest for their potential in diagnostics, therapeutics, and as biomarkers for a myriad of diseases. As the research community delves deeper into the microscopic marvels of EVs, the demand for technology advancement has surged. Learn more about how innovative tools from BD Biosciences can help you accelerate your discoveries. https://lnkd.in/em_yzWTM #BDBiosciences #flowcytometry #FACS

Are you attending the 29th Annual Meeting #RNA2024 of the The RNA Society in Edinburgh, Scotland? Don't miss Anahi Higuera´s poster presentation titled "Time-Dependent Binding of Molecules and Influence on RNA Modification: From Proteins to RNA-Based Therapeutics." Join Anahi to explore #switchSENSE, a cutting-edge biophysical technique for characterizing #RNA-binding proteins, nucleic acid aptamers, and antisense oligonucleotides. Connect with us on-site to dive into the world of molecular interactions and #drugdiscovery! #DiscoverMolecularInteractions

🍿 📽 In this video, we review the benefits of molecular therapies and their rise in prevalence. Discover the key role that plasmids play in the development and delivery of molecular therapeutics and the challenges presented by working with these constructs. #moleculartherapy #moleculartherapeutics #molecularmedicine #plasmiddna #plasmid #zymoresearch #zymoresearcheurope

My colleague, Omkar Kawalekar is discussing strategies to reduce batch to batch variation in cell therapy manufacturing. If you are in the cell therapy space and this challenge resonates with you, please join! Omkar Kawalekar Hussain Mooraj Laks Pernenkil Pete Lyons

📣ISCT 2024 is right around the corner, and we’d love to see you there! Looking to drive up batch productivity and drive down manufacturing COGS? Don’t miss our two presentations: ✔Poster Presentation: Evaluation of Small Molecule Antagonists of Cellular Innate Immunity for Efficient Manufacturing of T-cell Therapeutics. ✔Oral Presentation: Harnessing the Power of High-Throughput Virology and Design of Experiment for Rapid Vector Production Process Optimization. (9:15-10:15 PT, Friday, May 31st, 2024) 💡 Learn how we leverage the power of Viral Sensitizers (VSEs), high-throughput virology, and Design of Experiments (DoE) to rapidly optimize viral vector production and boost viral yields. 🤝 Connect with us to learn more: https://lnkd.in/gGXmj5Gu #innovation #biomanufacturing #ISCT2024

Developing oligonucleotide therapeutics? On the 21st May, I will be presenting a live webinar showcasing Patsnap's groundbreaking chemical modification search tool. Identifying modifications in sequences has previously been a laborious and incredibly time consuming task, but thanks to our comprehensive modification ontologies, and AI extraction model, these pains are a thing of the past. Come along to find out how we can revolutionise your oligonucleotide development. #RNA #oligonucleotide #innovation #chemicalmodification