Episode 4 of the R-Files is here. Longevity scientist Matt Kaeberlein discusses the results, methodology, and unanswered questions of research suggesting potential immune-boosting effects of rapamycin in mice and humans. https://lnkd.in/ghgc5kgR
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A study from the International Journal of Molecular Sciences reveals microplastics' impact on mice, showing behavioral changes and enhanced immune responses in young and old subjects. This expands our understanding of these pollutants. Source: PsyPost PsyPost Published Date: January 6, 2024 Author: Stacey Coleen Lubag #Microplastics #EnvironmentalHealth #ResearchDiscovery #MammalianImpact #ScienceInsights
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Our new preprint on out red squirrel genomics in Scotland, showing landscape-wide spatial structure and long-term depression in heterozygosity due to historical founder effects. https://lnkd.in/e92faui3
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From Spark to Stent: Unveiling the Physiology Secrets in the FIRE Trial for Older M.I. Population: Dr. Simone Biscaglia sheds light on the advantages of Supraflex Cruz within the Fire Trial study firsthand. Watch the full video: https://lnkd.in/dvkC_Y9q #FIREtrial #Supraflex #Cruz #Cardiosolutions
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Can you imagine measuring the pulse 📈 and strength 🏋♀️ of tiny beating heart muscles 💓 in space 🌌 for 26 days? We did it and the results are out: As the Smithsonian Institution nicely summarized, our partners Deok-Ho Kim, Devin Mair, and Jonathan Tsui, PhD from John Hopkins University have found that "the heart tissues had grown to beat half as strongly as the Earth-bound samples, and the period between beats stretched to five times longer. Heartbeat irregularity, known as arrhythmia, can cause heart failure, but the tissue’s contractions regained a normal cadence after returning to Earth. On a molecular level, sarcomeres—proteins that aid contraction—were shorter and disordered after space exposure, and cells’ mitochondria, responsible for energy production, had become deformed." Read the full publication here: https://lnkd.in/eEsp7emB
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National Neighborhood Data Archive researchers and colleagues recently published this incredible paper in PNAS Nexus, official journal of the National Academy of Sciences! To learn more about how the neighborhood socioeconomic environment gets under the skin to impact immune system aging, check out the full paper at https://lnkd.in/gH9En8SU.
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#JNeurosci: How can neuromodulator acetylcholine promote memory formation? Researchers from National Institute of Environmental Health Sciences (NIEHS) revealed a transient upregulation of oscillatory brain activities named theta rhythm in the hippocampus that is central for memory formation in mice. Learn more ▶️ https://bit.ly/45hrQ18
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#TPeducational - Understanding how 𝗰𝗶𝗿𝗰𝗮𝗱𝗶𝗮𝗻 𝗿𝗵𝘆𝘁𝗵𝗺𝘀 are regulated in different tissues is a prominent research focus, to learn how genetic, environmental and behavioral factors can contribute to increased 𝗿𝗶𝘀𝗸 𝗼𝗳 𝗺𝗲𝘁𝗮𝗯𝗼𝗹𝗶𝗰 𝗱𝗶𝘀𝗼𝗿𝗱𝗲𝗿𝘀. 𝗟𝗘𝗗𝗗𝗬 is the innovative 𝘄𝗶𝗿𝗲𝗹𝗲𝘀𝘀, 𝗳𝘂𝗹𝗹𝘆 𝗽𝗿𝗼𝗴𝗿𝗮𝗺𝗺𝗮𝗯𝗹𝗲 𝗜𝗩𝗖 𝗹𝗶𝗴𝗵𝘁𝗶𝗻𝗴 𝗰𝗼𝗻𝘁𝗿𝗼𝗹 𝘀𝘆𝘀𝘁𝗲𝗺 for circadian rhythms studies. ▶️ 𝗖𝗵𝗲𝗰𝗸 𝘁𝗵𝗲 𝘃𝗶𝗱𝗲𝗼 below and learn how every cage can be independently programmed with a specific light cycle, without interfering with adjacent cages. With LEDDY there’s 𝗻𝗼 𝗻𝗲𝗲𝗱 𝘁𝗼 𝗵𝗮𝘃𝗲 𝗮 𝗱𝗲𝗱𝗶𝗰𝗮𝘁𝗲𝗱 𝗿𝗼𝗼𝗺 𝘁𝗼 𝘀𝗲𝘁 𝘂𝗽 𝗮 𝗰𝗶𝗿𝗰𝗮𝗱𝗶𝗮𝗻 𝗿𝗵𝘆𝘁𝗵𝗺 𝘀𝘁𝘂𝗱𝘆. LEDDY improves the reproducibility if your studies thanks to the standardization of light intensity and time. 𝗦𝗶𝗺𝗽𝗹𝘆 𝗽𝗼𝘀𝗶𝘁𝗶𝗼𝗻 𝘁𝗵𝗲 𝗟𝗘𝗗𝗗𝗬 𝗰𝗮𝗴𝗲 𝗼𝗻 𝘆𝗼𝘂𝗿 𝗜𝗩𝗖 𝗿𝗮𝗰𝗸𝘀 𝘁𝗼 𝗯𝗲𝗴𝗶𝗻 𝘆𝗼𝘂𝗿 𝗱𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆!
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On #thisDayInScience in 1940, Oxford scientists revived Fleming’s work by testing #penicillin on mice with lethal streptococci. Those treated survived, showing penicillin’s remarkable effects. This led to mass production, saving countless lives in WWII and beyond.#Antibiotics Read this post and more on my Typeshare Social Blog: https://lnkd.in/gaDmzsm7
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Welcome to 'MicroMiracle,' the episode where we dive into the world of microRNA – the cellular superstars so small, yet so mighty, they've just been celebrated with a 𝐍𝐨𝐛𝐞𝐥 𝐏𝐫𝐢𝐳𝐞 𝐟𝐨𝐫 𝐭𝐡𝐞𝐢𝐫 𝐝𝐢𝐬𝐜𝐨𝐯𝐞𝐫𝐲! Join us as we unravel how these minuscule molecules act like master switches, controlling everything from eye color to disease resistance, right within our cells. We'll break down the science into bite-sized, easy-to-understand pieces, exploring how microRNA impacts our health, influences aging, and even shapes the future of medicine. Whether you're fascinated by biology or just curious about what makes you, tune in to discover why these 'micro' wonders are a 'macro' deal in the grand scheme of life! https://lnkd.in/e9n7ikf4
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Humans and naked mole rats are 2 outliers in the largely linear relationship between body size and aging across species (on a log scale). Matt Kaeberlein discusses how body size affects aging in our latest Longevity Science episode: https://lnkd.in/gDQJuqe8
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