Dispelling the myth that we're far from understanding MPN progression, MPN Research Foundation is at the forefront, driving collaboration across institutions to unlock the mysteries of MPN progression to acute myeloid leukemia (AML).
One of our funded Thrive initiatives, led by Dr. John Crispino in partnership with co-PI, Dr. Ayalew Tefferi of Mayo Clinic, and esteemed collaborators Drs. Charlotte Brierly, Adam Mead, and Beth Psaila, targets the DYRK1A gene on chromosome 21.
This collaborative research uncovers its amplification as a key factor in MPN to AML progression, demonstrating the power of cross-institutional collaboration in advancing our understanding of MPNs.
Supported by our 2022 Thrive award, this study exemplifies our commitment to not just understanding but also interrupting the progression of MPNs, signaling a pivotal leap towards enhancing patient outcomes.
We invite industry professionals and researchers to join our community, gaining insight into the impactful projects we fund and access to the MPN community and foundation-funded research. Together, we can foster groundbreaking discoveries and transformative solutions in the battle against MPNs.
Learn more about our collaborative efforts and how you can be part of this pioneering journey.
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