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With LP(a) garnering more interest by the day as a risk factor for cardiovascular disease, here is a great presentation summarizing the latest developments and potential treatments. #cardiachealth #pharma #biotech #medtech #clinicaltrials #innovation https://lnkd.in/egkJHAPZ
"Final year student | Clinical Pharmacy Enthusiast | Aspiring Researcher | Focused on Improving Patient Care”
Sucralfate Sucralfate forms a protective coat and protects the gastric mucosa from pepsin, pectic acid, and bile salts. This drug binds to positively charged proteins in exudates, locally forming a thick viscous substance. Brands available Ulsanic Surlka Ulcocid Mechanism of Action Sucralfate prevents hydrolysis by preventing the enzyme-substrate complex formation. This drug adsorbs pepsin and decreases its concentration. Clinical uses Sucralfate is a drug used to treat various medical conditions including duodenal ulcers, epithelial wounds, chemotherapy-induced mucositis Radiation proctitis Ulcers in Behçet disease.
https://lnkd.in/diCcGxrV Risk proritization: towards identifying factors making a patient succeptive towards drug-induced cholestasis, following intrahepatic bile acid accumulation.
NEW PUBLICATION: See the safety data results on the risk of Candida infections when treating PsA, PsO, and axSpA with an IL-17A inhibitor. View video summary and publication here: https://e.lilly/3TzJ8lm #PsoriaticArthritis #Psoriasis #AxialSpondyloarthritis
Fosinopril is another member of the angiotensin-converting enzyme (ACE) inhibitor class, similar to Benazopril and Captopril. It's primarily prescribed to treat high blood pressure (hypertension) and congestive heart failure. Fosinopril works by inhibiting the action of the enzyme ACE, which helps relax blood vessels and lower blood pressure. Compared to other ACE inhibitors, Fosinopril has a longer duration of action, allowing for once-daily dosing in most cases. Common side effects may include dizziness, cough, and low blood pressure. However, as with any medication, individual responses can vary, so it's crucial to follow your doctor's instructions and report any unusual symptoms or concerns.
PROPIONIC ACIDS :: These drugs are the first choice for inflammatory joint disease because they have the lowest incidence of side effects Gastrointestinal irritation and bleeding is less as compared to aspirin ibuprofen and ketoprofen have half life of 2 hours Fenbufen is a prodrug activated in the liver and https://lnkd.in/dGtgMuaC
Chief Biohacker TrueMedX & Neighborly Wellness | Regulatory Consultant & Expert Speaker | Contributor, American Journal of Endocannabinoid Medicine | Host of 'Chip Talks' Podcast | Chickasaw Citizen
Why are we messing around with UNSAFE drugs for weight loss? Apparently we have known since 2012 that an endocannabinoid receptor called GRP119 was responsible for GLP-1 release from L and B cells. Our upcoming drug is based on SAFE endocannabinoid actions. We will work WITH your body and WITH your bodies natural processes and use Nature to do so. It turns out as you begin to truly understand the power of the Endocannabinoid System it truly dictates that we are a HEALING MACHINE. We need some supplemental help sometimes, and we need to better understand what to eat and how to defend ourselves against pathogens, but we are a HEALING MACHINE. "The G protein-coupled receptor 119 (GPR119) mediates insulin secretion from pancreatic β cells and glucagon-like peptide 1 (GLP-1) release from intestinal L cells." https://lnkd.in/gw6UPiE3
What is the difference between tests for fibrinogen, d-dimer, and fibrin degradation products (FDP)? •Fibrinogen activity testing :evaluates the conversion of fibrinogen into fibrin •fibrinogen antigen testing measures the amount of soluble Factor I (dissolved in the blood) before it has been turned into insoluble fibrin and been crosslinked into a fibrin net. ✍D-dimer and FDP testing both help evaluate the status of the fibrinolytic system, the body's ability to break blood clots apart when they are no longer needed so that they can be removed. •FDP :is a measurement of all of the fragments of the dissolving clot •D-dimer: is a more specific measurement for one of the crosslinked, break-down fragments.
PRODUCT NAME: Exporam 40mg Capsule GENERIC NAME: Each Capsule Contains: Esomeprazole Magnesium trihydrate enteric coated pellets eq. to Esomeprazole………..40mg (USP SPEC's) PACK SIZE: 2x7's SUMMARY: Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory MODE OF ACTION: Esomeprazole works by binding irreversibly to the H+/K+ ATPase in the proton pump. Because the proton pump is the final pathway for secretion of hydrochloric acid by the parietal cells in the stomach, its inhibition dramatically decreases the secretion of hydrochloric acid into the stomach and alters gastric pH
#MRCPI exam journey Day 13 #Parkinson’s disease medications 1. First line is levodopa, which is given in early stages of the disease in combination with a dopa decarboxylase inhibitor such as co- beneldopa or co-careldopa. 2. Oral dopamine agonists. 3. MAO-B ( monoamine oxidase-B) inhibitors 4. COMT inhibitors 5. Amantadine 6. Subcutaneous apomorphine.
PN Update: Orphan designation: Cyclo(-gamma-aminobutyryl-L-phenylalanyl-L-tryptophanyl-D-tryptophanyl-L-lysyl-L-threonyl-L phenylalanyl-N-3-carboxypropyl)-glycine amide, acetate salt Treatment of acromegaly, 06/12/2012 Positive
