Primrose Bio’s Post

One of the key steps in the #westernblot workflow is the #transferofproteins from the polyacrylamide gel after electrophoresis to the nitrocellulose or polyvinylidene difluoride (PVDF) membrane so that specific proteins can be detected using immune-detection techniques in downstream. The Invitrogen™ #iBlot™ 3 Western Blot Transfer System is the latest generation of iBlot™, combining an innovative, all-new robust design that delivers exceptional performance and convenience with proven iBlot technology. Setup, teardown, and cleanup only takes minutes compared with the much more cumbersome and hands-on steps required for wet-tank transfer. Check this short to see how easy it is to make a protein transfer with the iBlot3. Want to know more: visit https://lnkd.in/dh9Nv-Xc

One of the key steps in the #westernblot workflow is the #transferofproteins from the polyacrylamide gel after electrophoresis to the nitrocellulose or polyvinylidene difluoride (PVDF) membrane so that specific proteins can be detected using immune-detection techniques in downstream. The Invitrogen™ #iBlot™ 3 Western Blot Transfer System is the latest generation of iBlot™, combining an innovative, all-new robust design that delivers exceptional performance and convenience with proven iBlot technology. Setup, teardown, and cleanup only takes minutes compared with the much more cumbersome and hands-on steps required for wet-tank transfer. Check this short to see how easy it is to make a protein transfer with the iBlot3. Want to know more: visit https://lnkd.in/dh9Nv-Xc

One of the key steps in the #westernblot workflow is the #transferofproteins from the polyacrylamide gel after electrophoresis to the nitrocellulose or polyvinylidene difluoride (PVDF) membrane so that specific proteins can be detected using immune-detection techniques in downstream. The Invitrogen™ #iBlot™ 3 Western Blot Transfer System is the latest generation of iBlot™, combining an innovative, all-new robust design that delivers exceptional performance and convenience with proven iBlot technology. Setup, teardown, and cleanup only takes minutes compared with the much more cumbersome and hands-on steps required for wet-tank transfer. Check this short to see how easy it is to make a protein transfer with the iBlot3. Want to know more: visit https://lnkd.in/dh9Nv-Xc

One of the key steps in the #westernblot workflow is the #transferofproteins from the polyacrylamide gel after electrophoresis to the nitrocellulose or polyvinylidene difluoride (PVDF) membrane so that specific proteins can be detected using immune-detection techniques in downstream. The Invitrogen™ #iBlot™ 3 Western Blot Transfer System is the latest generation of iBlot™, combining an innovative, all-new robust design that delivers exceptional performance and convenience with proven iBlot technology. Setup, teardown, and cleanup only takes minutes compared with the much more cumbersome and hands-on steps required for wet-tank transfer. Check this short to see how easy it is to make a protein transfer with the iBlot3. Want to know more: visit https://lnkd.in/dh9Nv-Xc

See below Axxam boot camp webinar on Solute Carrier Proteins

In the dynamic landscape of bioprocessing, where innovation is the key to success, MiD ProteinID® shines as a beacon of innovation, reshaping upstream processes to be smarter, more efficient, and incredibly cost-effective. Imagine harnessing the power of mass spectrometry precisely where you need it the most – seamlessly integrated into your bioprocessing workflow. Check out the latest video from Microsaic Systems featuring the MiD ProteinID®! https://lnkd.in/er65P4hh #Microsaic #MSYS #MiDProteinID #MiDPlatform #MassSpec #Bioprocessing #Innovation

Peptides are fast gaining traction in 2024, with #Semaglutide and #Tirzepatide at the top of the list! Both in today's pharma industry and in popular culture, these two products are hugely in demand. Now is the time for you to jump on the bandwagon to source these and other peptide APIs. In this webinar, get a holistic perspective on peptide APIs from a wide variety of experts including Tomer Simon, Nir Koyfman, Olga Pogrebinsky, Lior Stern and Keren Ofer. Mark your calendars - it's one you won't want to miss. Register here >> https://lnkd.in/ddNcckan #webinar #peptides #tevaapi #activepharmaceuticalingredients

Peptides are fast gaining traction in 2024, with #Semaglutide and #Tirzepatide at the top of the list! Both in today's pharma industry and in popular culture, these two products are hugely in demand. Now is the time for you to jump on the bandwagon to source these and other peptide APIs. In this webinar, get a holistic perspective on peptide APIs from a wide variety of experts including Tomer Simon, Nir Koyfman, Olga Pogrebinsky, Lior Stern and Keren Ofer. Mark your calendars - it's one you won't want to miss. Register here >> https://lnkd.in/d7dZ7h7D #webinar #peptides #tevaapi #activepharmaceuticalingredients

From the abstract: In this study, we present a comprehensive peptidomimetic structure–activity relationship (SAR) approach, combined with cellular NanoBRET target engagement assays to enhance the existing VHL ligands. Through systematic modifications of the molecule, we identified the 1,2,3-triazole group as an optimal substitute of the left-hand side amide bond that yields 10-fold higher binding activity. Moreover, incorporating conformationally constrained alterations on the methylthiazole benzylamine moiety led to the development of highly potent VHL ligands with picomolar binding affinity and significantly improved oral bioavailability. We anticipate that our optimized VHL ligand, GNE7599, will serve as a valuable tool compound for investigating the VHL pathway and advancing the field of targeted protein degradation.

Peptides are fast gaining traction in 2024, with #Semaglutide and #Tirzepatide at the top of the list! Both in today's pharma industry and in popular culture, these two products are hugely in demand. Now is the time for you to jump on the bandwagon to source these and other peptide APIs. In this webinar, get a holistic perspective on peptide APIs from a wide variety of experts including Tomer Simon, Nir Koyfman, Olga Pogrebinsky, Lior Stern and Keren Ofer. Mark your calendars - it's one you won't want to miss. Register here >> https://lnkd.in/d2C5Z6qF #webinar #peptides #tevaapi #activepharmaceuticalingredients