Mauro Dionisi’s Post

#Didyouknow From 01 July 2025, the rabbit pyrogen test #RPT will no longer be required as per new chapter adopted by European Pharmacopoeia Commission. An alternative in-vitro test (e.g. the monocyte-activation test) can be used to control the #pyrogenicity of a #medicinalproduct, based on a #riskassessment. Read more: https://lnkd.in/eUe3acms 📌The European Pharmacopoeia Commission adopted 57 revised texts from which the RPT has been deleted and added a new general chapter on Pyrogenicity (5.1.13). The revised texts will be published in Supplement 11.8 of the European Pharmacopoeia. Implementation date is the 1st of July 2025. #medtech #medicaldevices #medtechnews #biologicalsafety

In a couple of weeks Aranit Harizaj, Jan Van Hauwermeiren en Philip Mathuis will attend Advanced Therapies taking place in London March 19-20 and showcase Trince's gentle non-viral transfection technology. In a nutshell our platform is: ·         Very gentle, leading to high yields. ·         Versatile, we have experience with different cargo (DNA, siRNA, #mRNA, proteins, #CRISPR Cas, #CAR,…) and cell types (#iPSCs, #Tcells, #NKcells, #MSCs,…). ·         Proven to be an excellent tool for bio-imaging. ·         Ideal for screening since we can work with different vessels (flasks, 6 up to 384 well plates). ·         Fast: we can transfect all wells in less than 10 minutes (up to approx. 1M cells/sec) ·         We can transfect suspension and adherent cell lines (without trypsinization). ·         On track to become cGMP approved. We happily answer all your questions during the event, so don't hesitate to book a meeting through the conference app or via info@trincebio.com. #celltherapy #cellengineering #nonviral #celltherapymanufacturing #transfection

FDA approves break-through innovative gel to stop bleeding in seconds Aug 15, 2024 Severe blood loss can be life-threatening. It can kill in a matter of minutes, whether from a gunshot wound or a massive injury-related hemorrhage. At present several hemostatic agents and gauze bandages are available. Many products require preparation and lengthy application time. Cresilon’s Traumagel is a Hemostatic Gel, available in a 30 ml PFS. It is easy-to-apply at point of care , and requires no preparation. This revolutionary plant-based (algae- and fungi-based ) gel stops life-threatening bleeding quickly across all types of bleeds. traumagel’s “flowable” properties can improve the safety of treating a gunshot wound. Traumagel, will be launched later in 2024 #researchanddevelopment #innovation

FDA approves break-through innovative gel to stop bleeding in seconds Aug 15, 2024 Severe blood loss can be life-threatening. It can kill in a matter of minutes, whether from a gunshot wound or a massive injury-related hemorrhage. At present several hemostatic agents and gauze bandages are available. Many products require preparation and lengthy application time. Cresilon’s Traumagel is a Hemostatic Gel, available in a 30 ml PFS. It is easy-to-apply at point of care , and requires no preparation. This revolutionary plant-based (algae- and fungi-based ) gel stops life-threatening bleeding quickly across all types of bleeds. traumagel’s “flowable” properties can improve the safety of treating a gunshot wound. Traumagel, will be launched later in 2024 #researchanddevelopment #innovation #hemostatics #lifesavinggel #biotechnology #medicaldevices #criticalcare #biotechnology

In our upcoming webinar in partnership with Gyros Protein Technologies our experts will present a case study highlighting the advantages of using the Gyrolab® platform in clinical ADA method development to minimize matrix interference. Save your seat here >>> https://bit.ly/3tLYzNE

Join Ingrid Pan, Pharm.D, BCPPS, as she discusses the mechanism of action of Upadacitinib in this new FAQ video module! Discover how this JAK inhibitor works and its impact on treating various conditions. Check it out here: https://loom.ly/4ODUwZQ

🔬 PCR Workflow Made Simple! 🔬 Say goodbye to complicated setups and hello to streamlined efficiency! 🧪💡 Our infographic, sponsored by Promega Corporation , dives into the benefits of lyophilized master mix solutions—making your PCR workflow faster, more reliable, and easier to manage. Check it out and discover how you can save time without compromising results: https://bit.ly/3XYGVTb 📊 Explore the infographic now and share it with your fellow scientists—you know they’ll thank you! #PCR #LaboratoryScience #Lyophilization #ClinicalTesting

The #Digital #PCR (dPCR) allows sensitive and accurate absolute quantitation of nucleic acid samples without the need for a standard curve. Its improved precision and accuracy assist diagnosing various diseases at an early stage, monitoring treatment in higher resolution, and hence improving the recovery and survival rate of patients 𝐕𝐢𝐞𝐰 𝐅𝐮𝐥𝐥 𝐑𝐞𝐩𝐨𝐫𝐭 (https://lnkd.in/gHZ6a9gy) QIAGEN, Takara Bio Inc., Agilent Technologies, Promega Corporation , Abbott, bioMérieux, Thermo Fisher Scientific, RainDance Technologies, Fluidigm Sciences, Inc., JN Medsys #marketanalysis #marketgrowth #marketdata #marketsize #marketshare #markettrends #marketreport #marketoutlook #marketoverview #drivers #marketresearchreport #marketsegmentation #marketsummary #restraints #researchanddevelopment #researchmethods #researchreport #marketdemand

Concerned about cytokine stability in T cell media? PRIME-XV T Cell CDM supplemented with Shenandoah CTGrade GMP rh Proteins can withstand room temperature conditions for extended times and still perform as intended. See the data in our latest tech note “Stability of Cytokine-Supplemented PRIME-XV T Cell CDM at Room Temperature.” https://brnw.ch/21wLYEI

Bioanalysis of nicotine PK samples and nicotine pouches   At Lablytica Life Science AB, we are prepared to support you in the process of developing your nicotine product. Our fully validated nicotine in plasma analysis is semi-automated to allow us to deliver high quality results in record time. Along with our plasma analysis, we are also prepared to extract and analyze nicotine pouches to fulfill all your analytical needs. Our methods have been put to the test, already producing quality results for thousands of samples.    👉 Sounds interesting? Most welcome to contact us to find out how our high throughput nicotine analysis methods can help you with your next study.   #lablytica #bioanalysis #plasmaanalysis #nicotine #samples #pouches #weknowbioanalysis