Qiming Venture Partners’ Post

Are you struggling to unravel the complexities of the tumor microenvironment? Discover how cutting-edge technology is revolutionizing biomarker discovery in cancer research. Our friends at Ultivue have presented a game-changing solution. In a recent webinar, Dr. Angela Vasaturo, Director of Scientific Affairs at Ultivue, introduces a novel approach combining ultra-sensitive multiplex assays with AI-powered image analysis. By exploring this innovative method, you'll learn how to accelerate your biomarker discovery process and gain deeper insights into spatial biology. The presentation showcases a unique DNA-barcoded antibody technology that enables highly sensitive and robust multiplex biomarker detection, even for low-abundance targets. Don't miss this opportunity to enhance your research capabilities. Check out the webinar here: https://hubs.li/Q02HF5Hk0 #BiomarkerDiscovery #CancerResearch #SpatialBiology #BiotechWebinar #ImageAnalysis #Multiplex

Researchers at IRB Barcelona introduce #Oncodrive3D, a new computational tool that identifies cancer-causing genes by analyzing mutation clusters in protein structures. The tool leverages #AlphaFold2 to examine the entire human proteome, marking a significant advance over previous methods limited by incomplete protein structure data. According to the researchers, initial results suggest #Oncodrive3D can reveal new insights into cancer development mechanisms across different cancer types and in clonal hematopoiesis. Quick Read: https://lnkd.in/gg-rfjym #Bioinformatics #CancerResearch #AlphaFold #AIinBiology #ScienceNews

New potential avenues for cancer therapies through RNA-binding proteins. A new paper describes the role of two RNA-binding proteins in the development of sarcoma and carcinoma cancers, highlighting the important and emerging role of RNA-binding proteins in cancer research and offering a new avenue for therapeutic targets. Read: https://lnkd.in/e5XuQn3Q #sciencesdelavie #biotechnology #biotechnology #innovation #innovations #research #sciences #medicaments #research #drugresearch #laboratories #labs #chemistry #chemistry #biology #biologie #biopharma #rna #rnatherapeutics #arn #revolution #happ

Congratulations to Anthony Wilby, et al. & Hannah Harrison from Manchester Cancer Research Centre on the recent paper on "A novel preclinical model of the normal human breast"! The paper describes a normal breast explant model utilizing the xeno-free, tuneable hydrogel, VitroGel®, which helped maintain epithelial proliferation, hormone receptor expression, and residency of T cells and macrophages over 7 days. Unlike other organotypic tissue cultures, which are often limited by hyper-proliferation, loss of hormone signaling, and short treatment windows (<48h), the new model shows that tissue remains viable over 7 days with none of these early changes. 👁️🗨️Read the paper here: https://lnkd.in/gXvMufxB or explore the captivating webinar here: https://lnkd.in/g5VVFya2 Together, let's advance breast cancer research and work towards a future with fewer cases and improved outcomes. Move forward in your research. Animal-based ECM has its limitations. Explore the opportunities to enhance your studies through the utilization of the xeno-free VitroGel hydrogel system. https://lnkd.in/gk6v2MSc. #3DCellCulture #biotech #biotechnology #cellculture #organoid #stemcells #matrigel #cancerresearch #celltherapy #vitrogel #invivo #oncology #drugdiscovery #tissueengineering #regenerativemedicine #personalizedmedicine #precisionmedicine #cellbiology #lifescience #molecularbiology #VitroGelPublication

New potential avenues for cancer therapies through RNA-binding proteins. A new paper describes the role of two RNA-binding proteins in the development of sarcoma and carcinoma cancers, highlighting the important and emerging role of RNA-binding proteins in cancer research and offering a new avenue for therapeutic targets. Read: https://lnkd.in/eSpXZ2Qk #sciencesdelavie #biotechnology #biotechnology #innovation #innovations #research #sciences #medicaments #research #drugresearch #laboratories #labs #chemistry #chemistry #biology #biologie #biopharma #rna #rnatherapeutics #arn #revolution #happy

🚀 Innovation Alert: Roche’s Fully Automated Genomic Profiling Kit! 🧬 Roche is set to launch its tissue-based Comprehensive Genomic Profiling (CGP) Sequencing Kit in Q1 2025 — and it’s a game-changer for translational oncology research! 🎯 🌟 Key Features: ⏱️ Library preparation & target enrichment in just 24 hours. 🖐️ Only 3.5 hours of hands-on time, thanks to full automation. 🔬 Precision designed for tissue-based genomic profiling, advancing cancer research. This innovation promises to accelerate breakthroughs in oncology, empowering researchers with faster, more efficient workflows for personalized medicine. 💡 Let’s celebrate another leap towards better treatments and outcomes for patients. 👏 #Genomics #OncologyResearch #RocheInnovation #PrecisionMedicine #ComprehensiveGenomicProfiling #CancerResearch #BiotechBreakthroughs

Organoids in Cancer Biology: Advancements in Drug Screening and Clinical Utilization Excited to share insights on the transformative role of cancer organoids in biomedical research! Discover how these advanced models revolutionize biomarker discovery, drug screening, and personalized treatment in cancer research. Explore the latest advancements in organoids-on-a-chip technology and genomics integration, propelling new drug development and precision medicine forward. Join the discussion on LinkedIn to delve into the cutting-edge applications of cancer organoids in clinical trials across diverse fields! If you're curious about truthful information, please click the link below! https://lnkd.in/dqjJNqUH #CancerResearch #Organoids #PrecisionMedicine

⭐ 𝗣𝗢𝗦𝗧𝗘𝗥 𝗦𝗣𝗢𝗧𝗟𝗜𝗚𝗛𝗧 A #ThrowbackThursday to this posterpresented at the American Association for Cancer Research (AACR) 2020 and later selected for publication in Karger Publishers (link at the bottom of this post). The paper, ‘ICOS-Positive Regulatory T Cells in Hepatocellular Carcinoma: The Perspective from Digital Pathology Analysis‘, contains work from OracleBio alongside National Taiwan University Hospital and Kymab Ltd (now part of Sanofi). This study demonstrates the impact that Quantitative and Spatial Digital Pathology can have on understanding the expression of a novel therapeutic target in the context of Hepatocellular cancer (HCC) biology and patient outcomes. A fantastic collaboration! 🤝 Karger paper: https://lnkd.in/dqKy9XQA —— 👋 Liking our content? Follow us, OracleBio, for more image scientific posters, case studies, and opinions from our scientists. #digitalpathology #scientificposter #biotech #biopharma #cancerresearch #hepatocellularcarcinoma #spatialpathology #spatialanalysis #therapeutictargets #scientificpublication

🚀 Exciting New Publication Alert in Molecular Carcinogenesis! 🚀 I'm thrilled to share our latest research, now published in Molecular Carcinogenesis: "The Mechanism of TRIM21 Inhibiting the Invasion and Migration of ccRCC by Stabilizing ASS1." This study, conducted by our dedicated team at Kunming Medical University, dives into the molecular mechanisms behind clear cell renal cell carcinoma (ccRCC), a highly aggressive kidney cancer. 🔍 Key Highlights: We uncovered that TRIM21, a critical E3 ubiquitin ligase, plays a significant role in inhibiting ccRCC progression by stabilizing argininosuccinate synthase 1 (ASS1), an enzyme in the urea cycle. Our findings show that TRIM21 is often downregulated in ccRCC patients, which correlates with poorer outcomes. By stabilizing ASS1 through K63 ubiquitination, TRIM21 reverses urea cycle dysregulation, potentially limiting ccRCC's invasive characteristics. 💡 Implications for Cancer Therapy: This research fills a critical knowledge gap in ccRCC tumorigenesis and suggests that TRIM21 could be a promising therapeutic target, offering new pathways for tackling ccRCC's invasive nature. We hope these insights contribute to advancing treatment options and improving patient outcomes. A huge thank you to our co-authors, collaborators, and funding supporters at the National Natural Science Foundation of China and the Yunnan Province Applied Research Funds for making this work possible. To learn more, check out the full article in Molecular Carcinogenesis. https://lnkd.in/eN69HpB8 #Research #CancerResearch #RenalCellCarcinoma #TRIM21 #ccRCC #Biochemistry #MedicalResearch #Oncology #LinkedInResearch #wiley #molecularcarcinogenesis

Personalized Healing Exploring the Word of Cancer Biomarkers (Updated PDF 2023) Click Here Request PDF:- https://lnkd.in/gE9SqCFM The global 𝐂𝐚𝐧𝐜𝐞𝐫 𝐁𝐢𝐨𝐦𝐚𝐫𝐤𝐞𝐫𝐬 𝐌𝐚𝐫𝐤𝐞𝐭 is rapidly expanding, driven by advancements in genomics, proteomics, and personalized medicine. These biomarkers are critical in improving early detection, diagnosis, and treatment efficacy for various cancers. With increasing investment in precision medicine and rising cancer prevalence, the market is projected to see significant growth. Key players are focusing on biomarker discovery for tailored therapies, aiming to reduce side effects and improve survival rates. 🔬💡The future of cancer care lies in innovative biomarker technologies! #CancerResearch #PrecisionMedicine #Biotechnology #Oncology #CancerBiomarkers #HealthcareInnovation