Qubit Pharmaceuticals’ Post

There is still time to register to attend this exciting upcoming ''QM in Pharma'' 1-day meeting in London next month ! Event organised by Exscientia and Molecular Graphics and Modelling Society === QM in Pharma == SOAS, London, September 18th 2024    ==Synopsis Quantum Mechanics (QM) has established itself as a key tool in the pharmaceutical industry in areas such as elucidation of drug-target interactions, estimation of ligand binding affinities, descriptor calculation for QSPR/QSAR modelling and the prediction of molecular spectroscopic properties. The QM in Pharma meeting aims to highlight some of the key developments of quantum mechanics applied in the pharmaceutical industry and stimulate discussion about the future direction of new and emerging methodologies. We invite speakers to share their research focused on the following themes: – Quantum Mechanics or QM/MM approaches toward drug-target affinity or drug property prediction – Quantum Mechanics/Machine Learning models and their application to drug discovery problems – Quantum computing applications to drug discovery problems   == Confirmed speakers Fred Manby, Iambic Therapeutics, US David Pearlman, QSimulate, US Justin S. Smith , NVIDIA, US Jack Glancy, GSK, UK Georg Schusteritsch, Kuano, UK Christoph Riplinger, FACCTs, DE Beth Caine, Exscientia, UK   == Conference website  https://lnkd.in/ezJYMiGy #CADD #drugdiscovery #compchem #QM #machinelearning

From complex co-culture and organoids to microfluidics devices and microtissues, advanced in vitro platforms have the potential to revolutionize drug discovery. The MPS (Microphysiological Systems) World Summit 2023 kicked off in Berlin, bringing together over 1300 scientists and professionals from all over the world to discuss these tiny, but powerful, drug screening models. Axol CEO, Liam Taylor, and Product Manager, Jan Turner, attended to fly the flag for human iPSCs and how we're developing consistent, human-relevant cells at scale to fuel these advanced platforms. In this short article, we outline their 5 key highlights and takeaways from the Summit: https://hubs.la/Q021Dk-_0 Want to discuss how we can supply your MPS/microfluidics devices with consistent, high-quality iPSCs? Get in contact here: https://hubs.la/Q021Dkdj0 #iPSCs #organoids #microfluidics #OrganOnAChip #DrugDiscovery

5 Key Takeaways from The MPS (Microphysiological Systems) World Summit 2023 From complex co-culture and organoids to microfluidics devices and microtissues, advanced in vitro platforms have the potential to revolutionize drug discovery. In this short article, we outline their 5 key highlights and takeaways from the Summit: https://hubs.la/Q021Dk-_0 #biotechnology #mpsworldsummit #drugdevelopment #organonchip #biopharma #MPS #research #drugdiscovery

An interesting read on the role that quantum computing will potentially play in Life Sciences. The potential to revolutionize data science is tantalizing and major players are patenting and investing heavily (Amgen, Merck, Johnson & Johnson, Roche, AstraZeneca, Sanofi). Unlocking the ability to rapidly model complex interactions or match precision therapeutics to patients holds incredible potential. Conceptually, the balls are ready to start rolling. Practically, though, there is significant work to be done. The hardware and software needed to drive quantum computing to its potential is still in its infancy. https://lnkd.in/geMN99ak

Surface Plasmon Resonance (#SPR) #AffinityDetermination Services are revolutionizing the way we understand molecular interactions, particularly in the field of drug development and biomedical research. https://lnkd.in/g3RKU8au

A plasmonic platform that significantly improves the detection of the chirality of molecules, was developed by UCF NanoScience Technology Center professor Debashis Chanda. Chanda’s platform can quantify the purity of chiral enantiomers with a sensitivity nearly 13 orders of magnitude greater than the current method and provides cost savings due to the nanoimprinting based low-cost sensor fabrication, significantly lower concentrations and fewer molecules needed for accurate detection. #drugdevelopment #researchanddevelopment

The unique molecular fingerprint and non-destructive analysis provided by #Raman spectroscopy make it an ideal technique for drug identification and characterization. Read more about Raman, drug ID, and how the right optical filters make it all possible in our newest article from Hongbai Lao published by Photonics Online. https://lnkd.in/ekNA3AWV IDEX Optical Technologies

Exciting news! I've been invited to serve as a Guest Editor for the Journal Pharmaceutics MDPI for a special issue titled "Functional Nanomaterials for Drug Delivery in Photodynamic Therapy". I'm extending this invitation to all my colleagues to submit their manuscripts to this journal. If you're conducting groundbreaking research in this area, we want to hear from you! Please repost this announcement to ensure that no one misses this opportunity! Let's make advances in research together! Submit your manuscripts now. For more details on submission guidelines and the deadline, click here: https://shorturl.at/kxzAY #Nanomaterial #Drugdeliverysystems #Targetingagents #Nanotechnology #Nanoparticles #Nanomedicine #targetedtherapies #PhotodynamicTherapy #PDT #Photosensitizer #Thirdgenerationphotosensitizers #BiomedicalResearch #Pharmaceutics #MDPI #Specialissue #JournalPublication

🔬 Drs. Miyazaki and Cabral are transforming drug delivery with their groundbreaking Hoechst-based reporter system, providing unprecedented visibility into drug activation and target interaction. 🌐 Their research reveals key insights into the impact of drug-linker and nanoparticle properties on target-bound drug distribution. 🎯 💡 Drug engagement, defined as chemical detachment from a nanoparticle and binding to a subcellular target, is illuminated through nanoreporters. These nanoreporters examine how nanomedicine design influences drug distribution within subcellular targets, tracked via cellular nuclear fluorescence. 🚀 The versatile nanoplatform, compatible with common maleimide-based linkers, is applied to develop potent, targeted anticancer micelle nanoparticles delivering an MMAE prodrug. 🌟 Takuya Miyazaki, Ph.D. and Horacio Cabral's research expands our understanding of nanomedicine and paves the way for more effective and targeted therapies.  https://lnkd.in/d4WVnZwH 💊 #Nanomedicine #DrugDelivery #Innovation #ScienceAdvancements

TRC research chemicals are now fully available on the LGC Standards website. A better way to find the research chemicals needed for biopharma research along with all the reference materials you need for production. Everything at one site. View our entire solution for research, drug design and development, to drug manufacturing and qualification. Explore now at www.lgcstandards.com #ScienceForASaferWorld