Shree Mulay’s Post

For nephrology professionals and kidney disease patients: Our latest blog post explores lanthanum carbonate, its potential, and the ongoing debate about its long-term use. What are your thoughts? #TKE #kidneydisease #nephrology #phosphatebinder #hyperphosphatemia #research #healthcare https://lnkd.in/eNA7k7HR

We are fast approaching The Hypertension Scientific Sessions September 5-8th at the Hilton Chicago. Spacelabs looks forward each year to learning about the latest breakthroughs in hypertension research. This is where experts from various fields—cardiology, nephrology, endocrinology, and more—come together to explore the intricate connections between hypertension, cardiac health, kidney function, stroke risk, obesity, and even genetics. Will we see you there? #Hypertension24

https://lnkd.in/gSRYjqEq Article title: Implications of Vitamin D Deficiency in Chronic Kidney Disease - A Systematic Review Author(s): Paola Cristina Ceratto; Maiara Vanusa Guedes Ribeiro; Renata Calciolari Rossi e Silva; Debora Tavares de Resende e Silva* Journal: Archives of Clinical Nephrology Journal ISSN: 2581-3870 Abstract: Vitamin D presents interesting pleiotropic effects for the CKD patient (effect and anti-inflammatory properties). Patients with chronic kidney disease (CKD) have impaired endothelial function and the Vitamin D and its analogs may play a role in regulation of endothelial function and inflammation. Therefore, it is increasingly observed that CKD is characterized by a state of chronic inflammation that appears to be linked to oxidative stress, endothelial dysfunction and vascular calcification. Previous studies have shown that vitamin D administration in chronic renal failure patients produces therapeutic effects suggesting an inverse relationship between the presence of 25-hydroxyvitamin D [25 (OH) D] and inflammatory biomarkers. It is emphasized so the importance of proper maintenance of the vitamin D status, since it plays an important role in the management of inflammation and immunity, contributing to the reduction of morbidity and mortality in patients with CKD. In addition there is cumulative evidence showing the low level of vitamin D associations with the development and progression of chronic kidney disease, cardiovascular complications and high mortality. #VitaminD #ChronicKidneyDisease #Mortality #DiabeticNephropathy #ChronicKidneyDiseases #AcuteKidneyDisease #KidneyFibrosis #KidneyCalculi #RenalFailure #RenalTransplantation #ChronicHaemodialysis #RenalCancer #RenalImpairment #Glomerulonephritis #Urogynecology #ReconstructiveUrology #RenalHypertension #Nephrolithiasis #RenalImmunology #RenalPhysiology #RenalOsteodystrophy #RenovascularDisease #Peertechz #PeertechzPublications #ClinicalNephrology #PediatricNephrology #Neurourology #PediatricUrology #TubulointerstitialDisorders #GeriatricNephrology #Haematuria

https://lnkd.in/gtc_3nEM Article title: Some Aspects of the Evaluation of Brush Border Enzymuria Originating from Proximal Renal Tubules as Screening Test in Patients with Psoriatic Arthritis Author(s): Dejan Spasovski* Journal: Archives of Clinical Nephrology Journal ISSN: 2581-3870 Abstract: Aim: To compare diagnostic values and laboratory variables of alanine - aminopeptidase (microsomale AAP), γ-glutamyl transferase (γ−GT),β2-microglobuline (β2-M), C Reactive Protein (CRP) and index for disease activity (PASI) in early diagnosis in previously untreated Psoriatic arthritis (Psa). To determine the effect of untreated Psoriatic arthritis on tubular function, sensitivity of the Brush Border region as well as the diagnostic value of the enzymes originating from proximal renal tubules. #Alanine #Aminopeptidase #GammaGlutamylTransferase #Beta2Microglobulin #PsoriaticArthritis #DiabeticNephropathy #ChronicKidneyDiseases #AcuteKidneyDisease #KidneyFibrosis #KidneyCalculi #RenalFailure #RenalTransplantation #ChronicHaemodialysis #RenalCancer #RenalImpairment #Glomerulonephritis #Urogynecology #ReconstructiveUrology #RenalHypertension #Nephrolithiasis #RenalImmunology #RenalPhysiology #RenalOsteodystrophy #RenovascularDisease #Peertechz #PeertechzPublications #ClinicalNephrology #PediatricNephrology #Neurourology #PediatricUrology #TubulointerstitialDisorders #GeriatricNephrology #Haematuria

https://lnkd.in/gRxU3qTA Article title: Phenazopyridine abuse presenting with acute kidney injury, hemolytic anaemia and jaundice   Author(s): Jaya Prakash Nath Ambinathan*; Mohamed Elbokyl; Rory McQuillan   Journal: Archives of Clinical Nephrology   Journal ISSN: 2581-3870 Abstract: Phenazopyridine, an azo dye, is commonly used to relieve dysuria caused by bladder irritation or infection. We report the case of a 64-year-old lady who presented with unexplained sub-acute onset hemolytic anaemia followed by acute kidney injury (AKI) and jaundice. This created a diagnostic dilemma until concealed phenazopyridine abuse was discovered. Discontinuation of Phenazopyridine improved renal function and hemoglobin level to baseline without any other intervention. Prompt urinalysis proved crucial in solving the diagnostic challenge. We also present a review of literature highlighting the association of this commonly used medication with renal tubular dysfunction, interstitial nephritis and hemolytic anemia. #DiabeticNephropathy #ChronicKidneyDiseases #AcuteKidneyDisease #KidneyFibrosis #KidneyCalculi #RenalFailure #RenalTransplantation #ChronicHaemodialysis #RenalCancer #RenalImpairment #Glomerulonephritis #Urogynecology #ReconstructiveUrology #RenalHypertension #Nephrolithiasis #RenalImmunology #RenalPhysiology #Peertechz #PeertechzPublications #RenalOsteodystrophy #RenovascularDisease #ClinicalNephrology #PediatricNephrology #Neurourology #PediatricUrology #TubulointerstitialDisorders #GeriatricNephrology #Haematuria

https://lnkd.in/gh_kx8tF Article title: Release of lysosomal enzymes from kidney lysosomes in seronegative rheumatoid artritis   Author(s): Dejan Spasovski*   Journal: Archives of Clinical Nephrology   Journal ISSN: 2581-3870 Abstract: Introduction: To determine the effects of non-treated seronegative Rheumatoid Arthritis (RA) on proximal renal tubule, sensitivity of Alanine Aminopeptidase (AAP), γ-Glutamyltransferase (γ--GT), β2 Microglobulin in urine (β2M), as well as relation with Rheumatoid Factor (RF) and C-Reactive Protein (CRP), DAS 28 disease activity index. Methods: RF was determined by agglutination test (Latex) RF test, while kinetic methods were used for determination of Alanine Aminopeptidase (AAP) and γ-Glutamyltransferase (γ-GT), as well as MEIA (Microparticle Enzyme Immunoassay) to determine β2 microglobulin in urine. Samples (serum and urine) of 70 participants were examined (35 RA not treated, 35 health control group). #AlanineAminopeptidase #GammaGlutamylTransferase #Beta2Microglobulin #RheumatoidArthritis #RheumatoidFactor #DiabeticNephropathy #ChronicKidneyDiseases #AcuteKidneyDisease #KidneyFibrosis #KidneyCalculi #RenalFailure #RenalTransplantation #ChronicHaemodialysis #RenalCancer #RenalImpairment #Glomerulonephritis #Urogynecology #ReconstructiveUrology #RenalHypertension #Nephrolithiasis #RenalImmunology #RenalPhysiology #Peertechz #PeertechzPublications #RenalOsteodystrophy #RenovascularDisease #ClinicalNephrology #PediatricNephrology #Neurourology #PediatricUrology #TubulointerstitialDisorders #GeriatricNephrology #Haematuria

Do You Have Kidney Cysts? Hi, Would like to share some important information about cysts in the kidneys. Cysts are fluid-filled sacs that develop in the kidney. They are usually not dangerous and are seen in many in the general population. Usually, no treatment is needed except for drinking more water, which may help in the reduction of the size of the cyst with the help of anti-diuretic hormone. But when can they be dangerous? 1. When They Are Multiple and Complex: Multiple and complex cysts may develop cancer in them. Regular monitoring and medical attention are crucial in such cases. 2. ADPKD (Autosomal Dominant Polycystic Kidney Disease): This is a genetic condition where kidneys are filled with cysts, leading to kidney failure. It requires medical attention and management to slow down the progression of the disease. I hope this information helps in understanding kidney cysts better and encourages timely medical intervention when necessary. Dr. B. Vijay Kiran Former Assistant Professor Department of Nephrology Nizam's Institute of Medical Sciences, Hyderabad. Now - Senior consultant nephrologist and kidney transplant physician, Asian institute of nephrology and urology, Siliguri. #kidneycysts #kidney #kidneydisease #ADPKD #complexcyst #kidneydisease

🚨 Important Update for Patients and Health Professionals: FDA Warning on #Prolia and Advanced #CKD Attention patients, health professionals, and specialists in endocrinology, nephrology, and pharmacy: The #FDA has issued a critical update regarding the osteoporosis medication Prolia (denosumab). A completed review has concluded that Prolia increases the risk of severe hypocalcemia, particularly in patients with advanced chronic kidney disease (CKD), including those on dialysis. Severe hypocalcemia can present with symptoms such as confusion, seizures, irregular #heart rhythm, and #muscle spasms, and can lead to hospitalization or even be life-threatening. As a result, the FDA is adding a Boxed Warning, its most prominent warning, to the Prolia prescribing information. Patients considering or currently on Prolia treatment should discuss their kidney function and risk of severe hypocalcemia with their healthcare provider. Healthcare professionals are advised to assess patients' kidney function before prescribing Prolia and to closely monitor blood calcium levels, especially in patients with advanced CKD. Let's spread awareness of this crucial update to ensure patient safety and effective treatment management. Connect, Repost & Follow for more healthcare updates and recommendations 🌍 #PatientSafety #HealthcareProfessionals #Endocrinology #Nephrology #Pharmacy #FDAWarning #Prolia #ChronicKidneyDisease #PublicHealthAlert

https://lnkd.in/gyg8Ch6R Article title: Rapidly Progressive Glomerulonephritis Associated with Systemic Lupus Erythematosus Author(s): Jastrzębska K*; Gozdowska J; Perkowska-Ptasińska A; Durlik M Journal: Archives of Clinical Nephrology Journal ISSN: 2581-3870 Abstract: Lupus nephritis is a frequent manifestation of multisystem autoimmune disease - Systemic Lupus Erythematosus and a significant cause of both acute renal injury and the end stage renal disease. Renal involvement is observed in approximately 60% of patients with SLE. We report a case of crescentic glomerulonephritis in a previously healthy 21-year old man who showed signs of insidious symptoms (lower limbs and facial mild edema) in February 2011 and within a brief period developed such clinical features as fever, nausea, vomiting, headache, loin pain, hematuria, oliguria and hypertension. Rapidly worsening renal function became an important determinant of renal failure therefore hemodialysis therapy was introduced. #LupusNephritis #RapidlyProgressiveGlomerulonephritis #CrescenticGlomerulonephritis #DiabeticNephropathy #ChronicKidneyDiseases #AcuteKidneyDisease #KidneyFibrosis #KidneyCalculi #RenalFailure #RenalTransplantation #ChronicHaemodialysis #RenalCancer #RenalImpairment #Glomerulonephritis #Urogynecology #ReconstructiveUrology #RenalHypertension #Nephrolithiasis #RenalImmunology #RenalPhysiology #RenalOsteodystrophy #RenovascularDisease #Peertechz #PeertechzPublications #ClinicalNephrology #PediatricNephrology #Neurourology #PediatricUrology #TubulointerstitialDisorders #GeriatricNephrology #Haematuria

EC Pulmonology and Respiratory Medicine journal's article from Volume 13 issue 11 𝐀𝐫𝐭𝐢𝐜𝐥𝐞 𝐓𝐢𝐭𝐥𝐞: Antibiotics as a Cause of Stagnation in Solving the Problem of Acute Pneumonia 𝐀𝐮𝐭𝐡𝐨𝐫𝐬: Igor Klepikov* 𝐀𝐛𝐬𝐭𝐫𝐚𝐜𝐭: The discovery and use of antibiotics is rightfully considered one of the greatest discoveries in medicine of the 20th century, which allowed saving millions of lives. However, it was initially known that this direction of treatment could not have a long-term, much less permanent effect, quickly accompanied by side effects. Unfortunately, medicine has long concentrated its attention and sought to support only the therapeutic activity of these drugs, without paying due attention to their side effects. 𝐕𝐢𝐬𝐢𝐭 𝐜𝐨𝐦𝐩𝐥𝐞𝐭𝐞 𝐚𝐫𝐭𝐢𝐜𝐥𝐞 𝐡𝐞𝐫𝐞: https://lnkd.in/g8QFnZTq If you have any questions or need further information, reach me out: Phone: +44 7897 023755, E-Mail: pulmonology@ecronicon.net #Pulmonology #RespiratoryMedicine #Tuberculosis #Lungs #Asthama #ChestDisease #ECPRM #Submission #Research #Review #Casereport #Comorbidities #Onlinepublication #RheumatoidArthritis #LatentTuberculosis #AsthmaRemission #Predictors #RemissionofAsthma #AcutePneumonia #Etiology #Pathogenesis #Antibiotics #SideEffects #DiseaseConcept #Misconceptions