The Kidney Experts, PLLC’s Post

As someone in the healthcare/kidney disease community, I'm always interested in the latest research on phosphate binders. The potential benefits and safety concerns with lanthanum carbonate are worth considering. Curious to hear others' experiences or insights. #kidneydisease #nephrology #phosphatebinder #hyperphosphatemia #research #healthcare

We are fast approaching The Hypertension Scientific Sessions September 5-8th at the Hilton Chicago. Spacelabs looks forward each year to learning about the latest breakthroughs in hypertension research. This is where experts from various fields—cardiology, nephrology, endocrinology, and more—come together to explore the intricate connections between hypertension, cardiac health, kidney function, stroke risk, obesity, and even genetics. Will we see you there? #Hypertension24

https://lnkd.in/gRxU3qTA Article title: Phenazopyridine abuse presenting with acute kidney injury, hemolytic anaemia and jaundice   Author(s): Jaya Prakash Nath Ambinathan*; Mohamed Elbokyl; Rory McQuillan   Journal: Archives of Clinical Nephrology   Journal ISSN: 2581-3870 Abstract: Phenazopyridine, an azo dye, is commonly used to relieve dysuria caused by bladder irritation or infection. We report the case of a 64-year-old lady who presented with unexplained sub-acute onset hemolytic anaemia followed by acute kidney injury (AKI) and jaundice. This created a diagnostic dilemma until concealed phenazopyridine abuse was discovered. Discontinuation of Phenazopyridine improved renal function and hemoglobin level to baseline without any other intervention. Prompt urinalysis proved crucial in solving the diagnostic challenge. We also present a review of literature highlighting the association of this commonly used medication with renal tubular dysfunction, interstitial nephritis and hemolytic anemia. #DiabeticNephropathy #ChronicKidneyDiseases #AcuteKidneyDisease #KidneyFibrosis #KidneyCalculi #RenalFailure #RenalTransplantation #ChronicHaemodialysis #RenalCancer #RenalImpairment #Glomerulonephritis #Urogynecology #ReconstructiveUrology #RenalHypertension #Nephrolithiasis #RenalImmunology #RenalPhysiology #Peertechz #PeertechzPublications #RenalOsteodystrophy #RenovascularDisease #ClinicalNephrology #PediatricNephrology #Neurourology #PediatricUrology #TubulointerstitialDisorders #GeriatricNephrology #Haematuria

https://lnkd.in/gSRYjqEq Article title: Implications of Vitamin D Deficiency in Chronic Kidney Disease - A Systematic Review Author(s): Paola Cristina Ceratto; Maiara Vanusa Guedes Ribeiro; Renata Calciolari Rossi e Silva; Debora Tavares de Resende e Silva* Journal: Archives of Clinical Nephrology Journal ISSN: 2581-3870 Abstract: Vitamin D presents interesting pleiotropic effects for the CKD patient (effect and anti-inflammatory properties). Patients with chronic kidney disease (CKD) have impaired endothelial function and the Vitamin D and its analogs may play a role in regulation of endothelial function and inflammation. Therefore, it is increasingly observed that CKD is characterized by a state of chronic inflammation that appears to be linked to oxidative stress, endothelial dysfunction and vascular calcification. Previous studies have shown that vitamin D administration in chronic renal failure patients produces therapeutic effects suggesting an inverse relationship between the presence of 25-hydroxyvitamin D [25 (OH) D] and inflammatory biomarkers. It is emphasized so the importance of proper maintenance of the vitamin D status, since it plays an important role in the management of inflammation and immunity, contributing to the reduction of morbidity and mortality in patients with CKD. In addition there is cumulative evidence showing the low level of vitamin D associations with the development and progression of chronic kidney disease, cardiovascular complications and high mortality. #VitaminD #ChronicKidneyDisease #Mortality #DiabeticNephropathy #ChronicKidneyDiseases #AcuteKidneyDisease #KidneyFibrosis #KidneyCalculi #RenalFailure #RenalTransplantation #ChronicHaemodialysis #RenalCancer #RenalImpairment #Glomerulonephritis #Urogynecology #ReconstructiveUrology #RenalHypertension #Nephrolithiasis #RenalImmunology #RenalPhysiology #RenalOsteodystrophy #RenovascularDisease #Peertechz #PeertechzPublications #ClinicalNephrology #PediatricNephrology #Neurourology #PediatricUrology #TubulointerstitialDisorders #GeriatricNephrology #Haematuria

https://lnkd.in/gtc_3nEM Article title: Some Aspects of the Evaluation of Brush Border Enzymuria Originating from Proximal Renal Tubules as Screening Test in Patients with Psoriatic Arthritis Author(s): Dejan Spasovski* Journal: Archives of Clinical Nephrology Journal ISSN: 2581-3870 Abstract: Aim: To compare diagnostic values and laboratory variables of alanine - aminopeptidase (microsomale AAP), γ-glutamyl transferase (γ−GT),β2-microglobuline (β2-M), C Reactive Protein (CRP) and index for disease activity (PASI) in early diagnosis in previously untreated Psoriatic arthritis (Psa). To determine the effect of untreated Psoriatic arthritis on tubular function, sensitivity of the Brush Border region as well as the diagnostic value of the enzymes originating from proximal renal tubules. #Alanine #Aminopeptidase #GammaGlutamylTransferase #Beta2Microglobulin #PsoriaticArthritis #DiabeticNephropathy #ChronicKidneyDiseases #AcuteKidneyDisease #KidneyFibrosis #KidneyCalculi #RenalFailure #RenalTransplantation #ChronicHaemodialysis #RenalCancer #RenalImpairment #Glomerulonephritis #Urogynecology #ReconstructiveUrology #RenalHypertension #Nephrolithiasis #RenalImmunology #RenalPhysiology #RenalOsteodystrophy #RenovascularDisease #Peertechz #PeertechzPublications #ClinicalNephrology #PediatricNephrology #Neurourology #PediatricUrology #TubulointerstitialDisorders #GeriatricNephrology #Haematuria

https://lnkd.in/g5fRgAt2 Article title: Antiphosphlipid Syndrome Presented with Renovascular Hypertension Author(s): Savas Ozturk; Mukremin Uysal; Fulya Cosan; Banu Buyukaydin*; Murat Inanc; Reyhan Diz-Kucukkaya; Isın Kılıcarslan; Aydin Turkmen; Rumeyza Kazancioglu Journal: Archives of Clinical Nephrology Journal ISSN: 2581-3870 Abstract: Renovascular pathologies are one of the treatable causes of hypertension. Antiphospholipid syndrome develops owing to a heterogeneous group of antiphospholipid antibodies which causes various thrombotic problems. This entity may effects very small vessels and sometimes leads to hypertension. We present a 55-year-old female with unilateral renal artery stent implantation because of renovascular hypertension. After application, a re-stenosis developed and in-stent angioplasty was performed, but it was required a nephrectomy because of haemorrhage. #AntiphospholipidSyndrome #ChronicKidneyDisease #RenovascularHypertension #DiabeticNephropathy #ChronicKidneyDiseases #AcuteKidneyDisease #KidneyFibrosis #KidneyCalculi #RenalFailure #RenalTransplantation #ChronicHaemodialysis #RenalCancer #RenalImpairment #Glomerulonephritis #Urogynecology #ReconstructiveUrology #RenalHypertension #Nephrolithiasis #RenalImmunology #RenalPhysiology #RenalOsteodystrophy #RenovascularDisease #Peertechz #PeertechzPublications #ClinicalNephrology #PediatricNephrology #Neurourology #PediatricUrology #TubulointerstitialDisorders #GeriatricNephrology #Haematuria

https://lnkd.in/gh_kx8tF Article title: Release of lysosomal enzymes from kidney lysosomes in seronegative rheumatoid artritis   Author(s): Dejan Spasovski*   Journal: Archives of Clinical Nephrology   Journal ISSN: 2581-3870 Abstract: Introduction: To determine the effects of non-treated seronegative Rheumatoid Arthritis (RA) on proximal renal tubule, sensitivity of Alanine Aminopeptidase (AAP), γ-Glutamyltransferase (γ--GT), β2 Microglobulin in urine (β2M), as well as relation with Rheumatoid Factor (RF) and C-Reactive Protein (CRP), DAS 28 disease activity index. Methods: RF was determined by agglutination test (Latex) RF test, while kinetic methods were used for determination of Alanine Aminopeptidase (AAP) and γ-Glutamyltransferase (γ-GT), as well as MEIA (Microparticle Enzyme Immunoassay) to determine β2 microglobulin in urine. Samples (serum and urine) of 70 participants were examined (35 RA not treated, 35 health control group). #AlanineAminopeptidase #GammaGlutamylTransferase #Beta2Microglobulin #RheumatoidArthritis #RheumatoidFactor #DiabeticNephropathy #ChronicKidneyDiseases #AcuteKidneyDisease #KidneyFibrosis #KidneyCalculi #RenalFailure #RenalTransplantation #ChronicHaemodialysis #RenalCancer #RenalImpairment #Glomerulonephritis #Urogynecology #ReconstructiveUrology #RenalHypertension #Nephrolithiasis #RenalImmunology #RenalPhysiology #Peertechz #PeertechzPublications #RenalOsteodystrophy #RenovascularDisease #ClinicalNephrology #PediatricNephrology #Neurourology #PediatricUrology #TubulointerstitialDisorders #GeriatricNephrology #Haematuria

📃Scientific paper: Management of the congenital solitary kidney: consensus recommendations of the Italian Society of Pediatric Nephrology Abstract: Background In recent years, several studies have been published on the prognosis of children with congenital solitary kidney (CSK), with controversial results, and a worldwide consensus on management and follow-up is lacking. In this consensus statement, the Italian Society of Pediatric Nephrology summarizes the current knowledge on CSK and presents recommendations for its management, including diagnostic approach, nutritional and lifestyle habits, and follow-up. Summary of the recommendations We recommend that any antenatal suspicion/diagnosis of CSK be confirmed by neonatal ultrasound (US), avoiding the routine use of further imaging if no other anomalies of kidney/urinary tract are detected. A CSK without additional abnormalities is expected to undergo compensatory enlargement, which should be assessed by US. We recommend that urinalysis, but not blood tests or genetic analysis, be routinely performed at diagnosis in infants and children showing compensatory enlargement of the CSK. Extrarenal malformations should be searched for, particularly genital tract malformations in females. An excessive protein and salt intake should be avoided, while sport participation should not be restricted. We recommend a lifelong follow-up, which should be tailored on risk stratification, as follows: low risk: CSK with compensatory enlargement, medium risk: CSK without compensatory enlargement and/or additional CAKUT, and high risk: decreased GFR and/or proteinuria, and/or hypertens... Continued on ES/IODE ➡️ https://etcse.fr/CE7 ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you.

https://lnkd.in/gnNCmaED Article title: Closing the Mortality Gap in Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State: Implications of a Clinical Decision Support App   Author(s): Yair Saperstein; Joongheum Park; Samy I McFarlane   Journal: International Journal of Clinical Endocrinology and Metabolism   Journal ISSN: 2640-7582 Abstract: Case 1: A 65- year-old man was accidentally injured by wooden hammer on his top of head on 34 years before. He was suffered from vomiting, diarrhea and hypotension, and the laboratory examination revealed increased CRP level, hyponatremia and decreased plasma cortisol and ACTH levels, suggesting isolated ACTH deficiency and Crohn disease diagnosed by colonoscopic biopsy, and finally transferred to University Hospital. LH-RH, TRH, CRH and GHRP stimulation tests showed normal response of plasma pituitary hormones except for no response of plasma ACTH and cortisol levels by CRH stimulation. ACTH stimulation test showed no response of plasma cortisol levels although hydrocotisone replacement therapy had already been started. MRI imaging showed bottom of anterior lobe was crushed and pituitary gland was atrophied, which suggested brain might be injured by any strong trauma. #Diabetes #ClinicalDecisionSupport #EndocrineGlands #Hormones #HormoneMetabolism #StructureAndPhysiochemicalProperties #HormonalReceptors #SignalingMechanisms #HormoneRegulatedGeneExpression #IntracellularSteroidAndLipidMetabolism #BoneAndMineralMetabolism #Infertility #Peertechz #PeertechzPublications #SexualDifferentiation #Puberty #PediatricEndocrinology #EndocrinePharmacology #MolecularEndocrinology #GastrointestinalEndocrinology #Neuroendocrinology #ComparativeEndocrinology #CardiovascularEndocrinology #ReproductiveEndocrinology

https://lnkd.in/gyg8Ch6R Article title: Rapidly Progressive Glomerulonephritis Associated with Systemic Lupus Erythematosus Author(s): Jastrzębska K*; Gozdowska J; Perkowska-Ptasińska A; Durlik M Journal: Archives of Clinical Nephrology Journal ISSN: 2581-3870 Abstract: Lupus nephritis is a frequent manifestation of multisystem autoimmune disease - Systemic Lupus Erythematosus and a significant cause of both acute renal injury and the end stage renal disease. Renal involvement is observed in approximately 60% of patients with SLE. We report a case of crescentic glomerulonephritis in a previously healthy 21-year old man who showed signs of insidious symptoms (lower limbs and facial mild edema) in February 2011 and within a brief period developed such clinical features as fever, nausea, vomiting, headache, loin pain, hematuria, oliguria and hypertension. Rapidly worsening renal function became an important determinant of renal failure therefore hemodialysis therapy was introduced. #LupusNephritis #RapidlyProgressiveGlomerulonephritis #CrescenticGlomerulonephritis #DiabeticNephropathy #ChronicKidneyDiseases #AcuteKidneyDisease #KidneyFibrosis #KidneyCalculi #RenalFailure #RenalTransplantation #ChronicHaemodialysis #RenalCancer #RenalImpairment #Glomerulonephritis #Urogynecology #ReconstructiveUrology #RenalHypertension #Nephrolithiasis #RenalImmunology #RenalPhysiology #RenalOsteodystrophy #RenovascularDisease #Peertechz #PeertechzPublications #ClinicalNephrology #PediatricNephrology #Neurourology #PediatricUrology #TubulointerstitialDisorders #GeriatricNephrology #Haematuria