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Syreon Middle East is excited to share the publication of our recent scientific manuscript, Framework for Developing Cost-Effectiveness Analysis Threshold: The Case of Egypt. This collaborative effort introduces a Cost-Effectiveness Threshold (CET) framework meticulously crafted for the Egyptian healthcare landscape, emphasizing the relationship between health gains and economic benchmarks. Central to our findings, the national expert panel advocates for the establishment of variable CETs in Egypt linked to the GDP per capita. This approach permits each new healthcare intervention to be evaluated against a base threshold, augmented by specific multipliers reflecting relative health gains and the rarity of conditions. Key Insights: · A foundational threshold set at 1X the GDP per capita serves as the cornerstone, with potential amplification up to 3X, guided by the Incremental Relative Quality-Adjusted Life Years (QALY) Gain and rarity. · For orphan drugs, a special CET multiplier ranging from 1.5 to 3.0 was recommended, further refining the assessment based on disease rarity. · The framework proposes a differential approach to private reimbursement, recommending a multiplier of two compared to public sectors to reflect distinct economic realities. A thoughtful one-year pilot phase for the framework's implementation was strongly recommended by participants, ensuring a meticulous evaluation of its applicability and impact. We would like to thank our co-authors and research contributors for their commitment to enhancing health economics practices within Egypt and the MENA region Ahmad Fasseeh Nada Korra Baher ElEzbawy Amal Sedrak mary kirollos Randa Eldessouki Mariam El-Debeiky,MBA mohsen george Ahmed Seyam Asmaa Abourawash Ahmed Yehia Khalifa Mayada Shaheen Sherif Abaza ,MBA Zoltán Kaló . This publication reaffirms our dedication to supporting sustainable, evidence-based healthcare policies. We invite our community of healthcare experts, policymakers, and scholars to read the publication here: https://lnkd.in/gWBp7set #HealthEconomics #PublicHealth #Egypt #CostEffectiveness #HealthcarePolicy #InnovationInHealthcare

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Zoltán Kaló

Professor of Health Economics at Center for Health Technology Assessment, Semmelweis University

3mo

The paper represents an important milestone in the development of evidence-based health policy in #Egypt. Simple solutions, such as using single 3 times GDP per capita cost-effectiveness #threshold (usually promoted by inexperienced consultants as the "threshold value recommended by WHO") can be harmful for implementing #HTA in the pricing and reimbursement decisions of new health technologies. I thank all coauthors and collaborators for supporting this initaitive.

Assem Amer

GCC Market Access Manager at CSL Vifor | Driving Access for Orphan Drugs

3mo

Happy to witness this advancement in Egypt 🥰

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