Triducive®’s Post

Regular monitoring of chronic kidney disease (CKD) progression is crucial for timely interventions and treatment effectiveness assessment. Adults with CKD should undergo annual assessments of albuminuria, while children should be monitored for albuminuria/proteinuria and GFR at least annually. Understanding the variability of laboratory measurements in kidney disease is key to avoiding unnecessary changes in treatment strategies. Small fluctuations in GFR or albuminuria may not always signify clinically relevant progression. We consider the 95% confidence interval of test reproducibility for both estimated GFR (eGFR) and albumin-to-creatinine ratio (ACR) when determining thresholds for clinical evaluation. When observing changes in eGFR or ACR, it's essential to repeat the tests to differentiate between clinically significant progression of CKD and variations within biological and analytical variability. Children in the peripubescent phase require more frequent monitoring due to the high risk of progression during puberty. Individualized monitoring frequency should consider CKD severity, puberty stage, and recent progression rate. Monitoring CKD progression is a dynamic process that requires careful interpretation of changes in GFR and albuminuria. By adopting evidence-based monitoring practices, we aim to optimize patient care and treatment outcomes. Link to the 2024 KDIGO Guidelines: https://lnkd.in/gDVT83EE #KDIGO2024 #ClinicalPracticeGuideline #ESRD #CKD #ESKD #Kidneydisease #RenalFailure #RenalReplacment #dialysis #hemodialysis #ChronicKidneyDisease #KidneyHealth #PatientCare #MedicalMonitoring #Healthcare #Nephrology #MedicalPractice #HealthcareGuidelines

📅 Missed Eleva's webcast No. #Three on Oct. 17th? Get the gist and continue reading. ⬇️   👏👏👏 A heartfelt “Thank You” to our two fantastic guest speakers, Professor Sevcan Bakkaloğlu and Antonia King, for joining us last Thursday and for providing valuable insights into the #patientjourney and #pediatric aspects of diagnosing and treating #C3G.   Antonia's dual perspective as both a patient and speaker for Germany's leading self-help group, Selbsthilfe für seltene komplementvermittelte Erkrankungen e.V., how profound diseases like #C3G affect the patient's daily lives. The potential to improve the therapeutic options for patients like Antonia is what makes us come to work every day!   Sevcan shared a deep dive into the complement system and the prominent role of the #AlternativePathway in the physiology of #C3G. She also highlighted the need for continued research into novel treatment options and supporting biomarkers to manage complement disorders even better.   Meanwhile, our Factor H (CPV-104) program continues steadily towards the initiation of clinical studies to commence in 2025. As a recombinant version of human Factor H, CPV-104 has the potential to restore the natural balance in the complement system via the #AlternativePathway, thereby controlling over-activation while retaining its protective properties.   ⏯️ Feel free to watch the replay via: https://lnkd.in/euQKc_T6   #C3G #FactorH #complement #teameleva  

I'm proud to share and support this new American Heart Association Cardiovascular-Kidney-Metabolic Health Initiative to assess gaps in clinical care for cardiovascular-kidney-metabolic (CKM) syndrome patients, identify areas for future research and put science into practice to better treat this complex health threat! CKM syndrome was first defined by the American Heart Association in an October 2023 presidential advisory and scientific statement, both published in its flagship peer-reviewed scientific journal Circulation. About 1 in 3 U.S. adults have at least three risk factors for #ckmsyndrome, a health disorder related to the strong connections among cardiovascular disease, kidney disease and metabolic disease (such as Type 2 diabetes and obesity). As the underlying conditions of CKM syndrome worsen, the risk of heart attack, stroke, heart failure and kidney and liver diseases increase. This important initiative was made possible through the visionary leadership collective of people truly passionate about patients. Thank you to our founding sponsors Novo Nordisk and Boehringer Ingelheim and our many collaborators including American College of Physicians, American Diabetes Association, American Society of Nephrology, National Kidney Foundation, STOP Obesity Alliance at The George Washington University- Milken Institute School of Public Health and Cardiometabolic Center Alliance. The effort will engage 150 hospitals and sites across the nation, reaching more than 265,000 patients. You can follow this important initiative by visiting and bookmarking https://lnkd.in/dyWFU9C2. #cardiovasculardisease #kidneydiease #metabolicdisease #cardiometabolic #heartattack #stroke #heartfailure #kidney #liver #healthcare #medicine

Specialized neurologic care significantly improves the quality of life for children with complex neurologic diseases and their families, according to Dr. David Neil Toupin of Kentucky Children’s Hospital. Personalized, multidisciplinary care—delivered by a team of physicians, therapists, genetic counselors, and social workers—addresses the broad range of challenges these children face, from health issues like seizures and scoliosis to developmental and psychosocial difficulties. Recent advancements in treatments, such as gene therapy for Spinal Muscular Atrophy (SMA) and Duchenne Muscular Dystrophy (DMD), offer new hope, but require careful coordination among specialists. Beyond medical treatment, this collaborative approach provides crucial support for families, helping them navigate the emotional, physical, and financial challenges of caring for a child with a complex neurologic condition. Ultimately, specialized care goes beyond treating the disease; it focuses on improving the overall well-being of both the child and their family, ensuring the best possible outcomes now and in the future. #neurology #specialized #personalized With the Specialist combines artificial intelligence with a board certified neurologist to enhance neurological care in the primary care setting. When you don’t have access to a neurologist, we can help bring specialized neurologic care to you and your patients. #withthespecialist #aiinhealthcare #innovation https://lnkd.in/gzJzN8UZ https://lnkd.in/gExrwg2P

This high-level guide is designed to help #nephrologists initiate essential conversations about kidney disease with patients and their care partners. Kidney disease, including chronic kidney disease (CKD) and acute kidney injury (AKI), affects millions globally. Early detection, proactive management, and patient education are crucial in preventing disease progression to end-stage renal disease (ESRD), which requires dialysis or transplantation. The cheat sheet provides a concise overview of risk factors, stages of kidney disease, preventive strategies, lifestyle modifications, and holistic care practices. By using this guide, nephrologists can better educate patients about their condition, engage them in their care, and implement evidence-based preventive measures. This comprehensive approach aims to improve patient outcomes, enhance quality of life, and foster a collaborative care environment. Understanding and managing kidney disease holistically can significantly impact patients' health and well-being. #KidneyDisease #ChronicKidneyDisease #AcuteKidneyInjury #Nephrology #KidneyHealth #EarlyDetection #PatientEducation #PreventiveCare #HolisticHealth #KidneyCare #HealthManagement #PatientEngagement #KidneyDiseaseAwareness #CKD #ESRD #RenalHealth #HealthyLiving #MedicalGuide #HealthcareProfessionals #KidneySupport

A third of U.S. adults are at high risk for CKM syndrome, but many patients receive fragmented care. Today we are proud to launch an initiative to change that with American College of Physicians, American Diabetes Association, American Society of Nephrology, National Kidney Foundation, STOP Obesity Alliance at The George Washington University- Milken Institute School of Public Health and Cardiometabolic Center Alliance. Over the next four years, the Cardiovascular-Kidney-Metabolic Health Initiative will work to implement a person-centered approach to awareness, professional and patient education, and treatment of #CKMSyndrome. #cardiology #nephrology

On #WorldKidneyDay, let's remember that managing chronic kidney disease (CKD) requires a comprehensive approach. Providing CME/CE education to nephrologists and other HCPs can make a significant difference in the fight against CKD. Through this education, we can emphasize the latest treatment advances, guideline updates, evidence-based medicine, and real-world data. Let's champion these tools and holistic approaches for the benefit of our patients and prevent end-stage renal disease (ESRD). #CKD #CME #CE #nephrology #GlobalKidneyAcademy https://lnkd.in/dEMXykjY

📢Breaking news! Is the pathophysiology of #OropharyngealDysphagia the same in older, post-stroke, dementia or Parkinson's disease patients? Read our last article to find out! https://lnkd.in/d5qtpH8Q

The evolution of public attention in acute kidney injury and continuous renal replacement therapy: trends analysis from 2004 to 2024 @jingmiao2019 @NephMao @kianoushbk @MayoClinicNeph @FrontMedicine #Nephrology #AKI #CRRT #DigitalHealth https://lnkd.in/gsC5k4mp

Why implement Chronic Care Management for your Stage 3a and 3b patients? Ishan Ghildyal hears from a lot of nephrologists who are deciding whether to implement chronic care management for their patients with earlier-stage Chronic Kidney Disease. Here's his advice. #nephrology #chroniccaremanagement #chronickidneydisease