🔬 Molecular chemist Alice Ting and her team at Stanford University have devised a new tagging system that enables scientists to track protein traffic in living cells. This new method, dubbed "TransitID," was detailed in a paper published in Cell Press in 2023. 🇹🇼 Born in Taiwan, Ting received The Vilcek Foundation Prize for Creative Promise in Biomedical Science in 2012 for the development of sophisticated tools for the detection and visualization of individual biomolecules. 🔗 Read more on Ting's research and the potential for TransitID in the following article from Stanford University. #BiomedicalResearch #BiomedicalScience #DiversityinScience #DiversityinSTEM #Stanford #StanfordUniversity #WomeninScience #WomeninSTEM
The Vilcek Foundation’s Post
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** 𝐖𝐞𝐛𝐢𝐧𝐚𝐫 𝐀𝐥𝐞𝐫𝐭! ** [[ 𝐂𝐫𝐚𝐜𝐤𝐢𝐧𝐠 𝐁𝐚𝐬𝐢𝐜 𝐭𝐨 𝐓𝐫𝐚𝐧𝐬𝐥𝐚𝐭𝐢𝐨𝐧𝐚𝐥 𝐁𝐢𝐨𝐥𝐨𝐠𝐲 𝐰𝐢𝐭𝐡 𝐒𝐩𝐚𝐭𝐢𝐚𝐥 𝐏𝐫𝐨𝐭𝐞𝐨𝐦𝐢𝐜𝐬 ]] 𝐑𝐞𝐠𝐢𝐬𝐭𝐞𝐫 𝐍𝐨𝐰: https://lnkd.in/gBQCNc3W Leaps in imaging, mass spectrometry-based proteomics, protein engineering, and chemical probe technologies have empowered the study of the proteome at increasingly smaller resolutions. Instead of associating protein abundance at the organ or cell level with normal and disease physiology, it is possible to understand how subcellular trafficking and localization contribute to pathology. With the advancement of these technologies, several new approaches can be used to achieve a spatial view of the proteome. In this encore Cell Press Webinar, sponsored by Akoya Biosciences, Inc., Kathryn Lilley (University of Cambridge), Garry Nolan (Stanford University), and Jeffrey Spraggins (Vanderbilt University School of Medicine) will discuss the opportunities and challenges of using spatial proteomics to tackle basic research to disease biology. [[ Details ]] 📆Date: Jan 24, 2024 ⏰Time: 09:00 PM Singapore 😀Speakers: Kathryn Lilley - Professor, Department of Biochemistry; Director, Cambridge Centre for Proteomics University of Cambridge Garry Nolan - Rachford and Carlota A. Harris Professor, Stanford School of Medicine Jeffrey Spraggins - Associate Professor, Department of Cell & Developmental Biology; Director, VU Biomolecular Multimodal Imaging Center School of Medicine, Vanderbilt University --------------------- Contact us now for more details! 😉 🌐www.gaiascience.com.sg ☎️+65 6897 2772 📨enquiry@gaiascience.com.sg #webinar #gaiascience #akoyabiosciences #spatial #multiomics #research #disease
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Very interesting read on the rise of automation in proteomics. Check it out below!
A very timely article in Genetic Engineering and Biotechnology News from Opentrons’ own James Atwood and our friend Joao Paulo at Harvard Medical School on the rise of automation in proteomics! The article underscores the dominant role of mass spectrometry in advancing proteomic research, highlighting how recent technological advancements have continued to eclipse improvements in other approaches. From single-cell analysis to unbiased discovery proteomics, mass spectrometry researchers now have unprecedented tools at their disposal to study thousands of proteins with remarkable speed and efficiency. One key takeaway is the importance of automation in overcoming the upstream bottleneck of sample preparation—a challenge that Dr. Paulo overcame using his Opentrons robot. Our newly launched Flex robot offers a cutting-edge solution for streamlining sample processing, enabling sample preparation to keep pace with proteomic analysis. The article also features success stories from institutions like Universitätsmedizin Greifswald and the Københavns Universitet - University of Copenhagen, where Opentrons robots have played a pivotal role in accelerating proteomic research. From reducing hands-on time to enabling complete automation of sample preparation, our technology is driving innovation and efficiency across the proteomics landscape. As we look ahead, the integration of automation into proteomics promises to unlock even greater possibilities, empowering scientists to delve deeper into the proteome and revolutionize our understanding of disease. At Opentrons, we're committed to advancing the frontiers of laboratory automation, empowering researchers to focus on what matters most—scientific breakthroughs. Read the article in GEN: https://bit.ly/3Wlw6tN Links to more proteomics automation resources in the comments! #Proteomics #LabAutomation #Innovation #Opentrons #FlexRobot #MassSpectrometry
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Very interesting read on the rise of automation in proteomics. Check it out below!
A very timely article in Genetic Engineering and Biotechnology News from Opentrons’ own James Atwood and our friend Joao Paulo at Harvard Medical School on the rise of automation in proteomics! The article underscores the dominant role of mass spectrometry in advancing proteomic research, highlighting how recent technological advancements have continued to eclipse improvements in other approaches. From single-cell analysis to unbiased discovery proteomics, mass spectrometry researchers now have unprecedented tools at their disposal to study thousands of proteins with remarkable speed and efficiency. One key takeaway is the importance of automation in overcoming the upstream bottleneck of sample preparation—a challenge that Dr. Paulo overcame using his Opentrons robot. Our newly launched Flex robot offers a cutting-edge solution for streamlining sample processing, enabling sample preparation to keep pace with proteomic analysis. The article also features success stories from institutions like Universitätsmedizin Greifswald and the Københavns Universitet - University of Copenhagen, where Opentrons robots have played a pivotal role in accelerating proteomic research. From reducing hands-on time to enabling complete automation of sample preparation, our technology is driving innovation and efficiency across the proteomics landscape. As we look ahead, the integration of automation into proteomics promises to unlock even greater possibilities, empowering scientists to delve deeper into the proteome and revolutionize our understanding of disease. At Opentrons, we're committed to advancing the frontiers of laboratory automation, empowering researchers to focus on what matters most—scientific breakthroughs. Read the article in GEN: https://bit.ly/3Wlw6tN Links to more proteomics automation resources in the comments! #Proteomics #LabAutomation #Innovation #Opentrons #FlexRobot #MassSpectrometry
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Very interesting read on the rise of automation in proteomics. Check it out below!
A very timely article in Genetic Engineering and Biotechnology News from Opentrons’ own James Atwood and our friend Joao Paulo at Harvard Medical School on the rise of automation in proteomics! The article underscores the dominant role of mass spectrometry in advancing proteomic research, highlighting how recent technological advancements have continued to eclipse improvements in other approaches. From single-cell analysis to unbiased discovery proteomics, mass spectrometry researchers now have unprecedented tools at their disposal to study thousands of proteins with remarkable speed and efficiency. One key takeaway is the importance of automation in overcoming the upstream bottleneck of sample preparation—a challenge that Dr. Paulo overcame using his Opentrons robot. Our newly launched Flex robot offers a cutting-edge solution for streamlining sample processing, enabling sample preparation to keep pace with proteomic analysis. The article also features success stories from institutions like Universitätsmedizin Greifswald and the Københavns Universitet - University of Copenhagen, where Opentrons robots have played a pivotal role in accelerating proteomic research. From reducing hands-on time to enabling complete automation of sample preparation, our technology is driving innovation and efficiency across the proteomics landscape. As we look ahead, the integration of automation into proteomics promises to unlock even greater possibilities, empowering scientists to delve deeper into the proteome and revolutionize our understanding of disease. At Opentrons, we're committed to advancing the frontiers of laboratory automation, empowering researchers to focus on what matters most—scientific breakthroughs. Read the article in GEN: https://bit.ly/3Wlw6tN Links to more proteomics automation resources in the comments! #Proteomics #LabAutomation #Innovation #Opentrons #FlexRobot #MassSpectrometry
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Outside Sales Representative | Automation Specialist @ Opentrons | Making the world better by making the lives of scientists easier
Very interesting read on the rise of automation in proteomics. Check it out below!
A very timely article in Genetic Engineering and Biotechnology News from Opentrons’ own James Atwood and our friend Joao Paulo at Harvard Medical School on the rise of automation in proteomics! The article underscores the dominant role of mass spectrometry in advancing proteomic research, highlighting how recent technological advancements have continued to eclipse improvements in other approaches. From single-cell analysis to unbiased discovery proteomics, mass spectrometry researchers now have unprecedented tools at their disposal to study thousands of proteins with remarkable speed and efficiency. One key takeaway is the importance of automation in overcoming the upstream bottleneck of sample preparation—a challenge that Dr. Paulo overcame using his Opentrons robot. Our newly launched Flex robot offers a cutting-edge solution for streamlining sample processing, enabling sample preparation to keep pace with proteomic analysis. The article also features success stories from institutions like Universitätsmedizin Greifswald and the Københavns Universitet - University of Copenhagen, where Opentrons robots have played a pivotal role in accelerating proteomic research. From reducing hands-on time to enabling complete automation of sample preparation, our technology is driving innovation and efficiency across the proteomics landscape. As we look ahead, the integration of automation into proteomics promises to unlock even greater possibilities, empowering scientists to delve deeper into the proteome and revolutionize our understanding of disease. At Opentrons, we're committed to advancing the frontiers of laboratory automation, empowering researchers to focus on what matters most—scientific breakthroughs. Read the article in GEN: https://bit.ly/3Wlw6tN Links to more proteomics automation resources in the comments! #Proteomics #LabAutomation #Innovation #Opentrons #FlexRobot #MassSpectrometry
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A very timely article in Genetic Engineering and Biotechnology News from Opentrons’ own James Atwood and our friend Joao Paulo at Harvard Medical School on the rise of automation in proteomics! The article underscores the dominant role of mass spectrometry in advancing proteomic research, highlighting how recent technological advancements have continued to eclipse improvements in other approaches. From single-cell analysis to unbiased discovery proteomics, mass spectrometry researchers now have unprecedented tools at their disposal to study thousands of proteins with remarkable speed and efficiency. One key takeaway is the importance of automation in overcoming the upstream bottleneck of sample preparation—a challenge that Dr. Paulo overcame using his Opentrons robot. Our newly launched Flex robot offers a cutting-edge solution for streamlining sample processing, enabling sample preparation to keep pace with proteomic analysis. The article also features success stories from institutions like Universitätsmedizin Greifswald and the Københavns Universitet - University of Copenhagen, where Opentrons robots have played a pivotal role in accelerating proteomic research. From reducing hands-on time to enabling complete automation of sample preparation, our technology is driving innovation and efficiency across the proteomics landscape. As we look ahead, the integration of automation into proteomics promises to unlock even greater possibilities, empowering scientists to delve deeper into the proteome and revolutionize our understanding of disease. At Opentrons, we're committed to advancing the frontiers of laboratory automation, empowering researchers to focus on what matters most—scientific breakthroughs. Read the article in GEN: https://bit.ly/3Wlw6tN Links to more proteomics automation resources in the comments! #Proteomics #LabAutomation #Innovation #Opentrons #FlexRobot #MassSpectrometry
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Very interesting read on the rise of automation in proteomics. Check it out below!
A very timely article in Genetic Engineering and Biotechnology News from Opentrons’ own James Atwood and our friend Joao Paulo at Harvard Medical School on the rise of automation in proteomics! The article underscores the dominant role of mass spectrometry in advancing proteomic research, highlighting how recent technological advancements have continued to eclipse improvements in other approaches. From single-cell analysis to unbiased discovery proteomics, mass spectrometry researchers now have unprecedented tools at their disposal to study thousands of proteins with remarkable speed and efficiency. One key takeaway is the importance of automation in overcoming the upstream bottleneck of sample preparation—a challenge that Dr. Paulo overcame using his Opentrons robot. Our newly launched Flex robot offers a cutting-edge solution for streamlining sample processing, enabling sample preparation to keep pace with proteomic analysis. The article also features success stories from institutions like Universitätsmedizin Greifswald and the Københavns Universitet - University of Copenhagen, where Opentrons robots have played a pivotal role in accelerating proteomic research. From reducing hands-on time to enabling complete automation of sample preparation, our technology is driving innovation and efficiency across the proteomics landscape. As we look ahead, the integration of automation into proteomics promises to unlock even greater possibilities, empowering scientists to delve deeper into the proteome and revolutionize our understanding of disease. At Opentrons, we're committed to advancing the frontiers of laboratory automation, empowering researchers to focus on what matters most—scientific breakthroughs. Read the article in GEN: https://bit.ly/3Wlw6tN Links to more proteomics automation resources in the comments! #Proteomics #LabAutomation #Innovation #Opentrons #FlexRobot #MassSpectrometry
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Introducing The Lab for Molecular Biology of Aging, led by Dr. Bar Daniel Zvi. The lab addresses the critical need to understand and treat the aging process, as it remains the primary risk factor for many diseases. Employing innovative methods, such as novel protein environment analysis and proximity-labeling techniques, the lab investigates age-related changes in subcellular structures and DNA-protein interactions. By comprehensively exploring these mechanisms, the lab aims to contribute to the modulation of aging and ultimately improve healthspan and lifespan. To learn more about this lab, its capabilities and potential applications, please contact Tali Aloya, Ph.D., VP of Business Development in Life Sciences at Ramot: tali.aloya@Ramot.org #aging #biology #lab #innovation #research #researchinnovation #longevity
The lab for Molecular Biology of Aging - Ramot
ramot.org
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Observing #proteins precisely within #cells is extremely important for many branches of research but has been a significant technical challenge—especially in living cells, as the required #fluorescentlabeling had to be individually attached to each protein. The research group at CeMM has overcome this hurdle: With a method called "vpCells," it is possible to label many proteins simultaneously, using five different fluorescent colors. This automated high-throughput approach, aided by #artificialinteligence AI-assisted image recognition, opens up entirely new applications in various disciplines, from fundamental cell biology to drug discovery #biopharma. The study has been published in the journal Nature Cell Biology. To understand and explore the function of proteins, it is essential to precisely determine and track their location within the cell. Proteins often shuttle dynamically between different organelles and compartments of the cell. To visualize them under the microscope, they are often linked to a fluorescent, brightly shining protein component. However, this method has faced technical difficulties: Typically, the fluorescent component could only be attached to one protein at a time, and to label multiple proteins, cells usually had to be killed and fixed. #nih #cdc https://lnkd.in/eT94ydac
Light show in living cells: New method allows simultaneous fluorescent labeling of many proteins
phys.org
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🔬 Exciting News for Scientists! 🔬 Introducing: Nature Springer’s Borrelia burgdorferi: Methods and Protocols. Methods in Molecular Biology. Editor Leona Gilbert. https://lnkd.in/dyW8d6V6 📚 From cell and molecular biologists to statisticians and clinical researchers, these methods cater to all fields. Explore techniques for in vitro, in vivo, in situ, de novo, and clinical studies of Borrelia burgdorferi. Let's advance our understanding of infectious diseases! 💪🌍 Chapter 9 Revealed. 🔬 New Insights in Lyme Disease Research 🔍 Excited to share the latest chapter in clinical proteomics, pushing the boundaries of what's possible with the analysis of Borrelia-derived peptides in human urine. 🧬💧 Cornero and colleagues have developed a cutting-edge method that combines advanced mass spectrometry with enrichment-based sample preparation, significantly enhancing the analytical capabilities of clinical proteomics. A strong bioinformatic peptide authentication algorithm supports this novel approach, which also uses a sample affinity enrichment method and liquid chromatography tandem mass spectrometry analysis. Stay tuned for more details on how this breakthrough could pave the way for new diagnostics and a better understanding of #Borrelia infections. #ClinicalProteomics #MassSpectrometry #MedicalResearch #InnovationInHealthcare #LymeDisease #BorreliaBurgdorferi
