Xaira Therapeutics’ Post

DNA polymerase plays a key role in synthesizing new DNA strands. Because of the sensitive and specific nature of PCR, it is important to choose high-quality enzymes and reagents to produce optimal results.  Watch this webinar for tips to optimize PCR reagents and enzymes for your experiment: https://lnkd.in/gbjwGrTx #DNAPolymerase #PCREnzyme #PCR #iloveMolBio #MolecularBiology

DNA polymerase plays a key role in synthesizing new DNA strands. Because of the sensitive and specific nature of PCR, it is important to choose high-quality enzymes and reagents to produce optimal results.  Watch this webinar for tips to optimize PCR reagents and enzymes for your experiment: https://lnkd.in/gbjwGrTx #DNAPolymerase #PCREnzyme #PCR #iloveMolBio #MolecularBiology

DNA polymerase plays a key role in synthesizing new DNA strands. Because of the sensitive and specific nature of PCR, it is important to choose high-quality enzymes and reagents to produce optimal results.  Watch this webinar for tips to optimize PCR reagents and enzymes for your experiment: https://lnkd.in/gbjwGrTx #DNAPolymerase #PCREnzyme #PCR #iloveMolBio #MolecularBiology

DNA polymerase plays a key role in synthesizing new DNA strands. Because of the sensitive and specific nature of PCR, it is important to choose high-quality enzymes and reagents to produce optimal results.  Watch this webinar for tips to optimize PCR reagents and enzymes for your experiment: https://lnkd.in/gbjwGrTx #DNAPolymerase #PCREnzyme #PCR #iloveMolBio #MolecularBiology

DNA polymerase plays a key role in synthesizing new DNA strands. Because of the sensitive and specific nature of PCR, it is important to choose high-quality enzymes and reagents to produce optimal results.  Watch this webinar for tips to optimize PCR reagents and enzymes for your experiment: https://lnkd.in/gbjwGrTx #DNAPolymerase #PCREnzyme #PCR #iloveMolBio #MolecularBiology

DNA polymerase plays a key role in synthesizing new DNA strands. Because of the sensitive and specific nature of PCR, it is important to choose high-quality enzymes and reagents to produce optimal results.  Watch this webinar for tips to optimize PCR reagents and enzymes for your experiment: https://lnkd.in/gbjwGrTx #DNAPolymerase #PCREnzyme #PCR #iloveMolBio #MolecularBiology

📊💊 Join this exciting webinar on February 28, exploring the synthesis structural impact of posttranslational modifications on disordered proteins with Dr. Anne C. Conibear. Don't miss this unique chance to stay at the forefront of chemical protein synthesis! REGISTER HERE: https://buff.ly/3I7wkg5 💡 What you will learn:  👉🏽 How posttranslational modifications regulate the structures and biological roles of proteins 👉🏽Strategies for accessing proteins with site-specific posttranslational modifications for structural and biochemical experiments 👉🏽Considerations and approaches to manual and automated synthesis of modified peptides 👉🏽Practical strategies for addressing some of the challenges of synthesizing difficult sequences Our Field Application Specialist Luísa Aguiar will join Anne in a special interactive part of the webinar to explore challenges and solutions for the synthesis of complex peptides. #peptide #synthesis #purification #purepep

#ICYMI: Sapient has expanded our metabolite identification capabilities to further enhance & accelerate small molecule #biomarkerdiscovery. Read the full #pressrelease to learn how our comprehensive Metabolite Standards Library, comprised of >10,000 chemical reference standards and enabling Tier 1 identifications for more than 1,000 metabolites and lipids routinely measured in human plasma, brings critical scientific value to discovery #metabolomics and #lipidomics screenings in two key ways: 1) Providing the highest possible confidence to #biomarker identification using multi-parameter data 2) Enabling putative structural insights for hundreds to thousands of additional unknown #metabolites and #lipids, enabling advancement of novel discoveries Read more: https://lnkd.in/gNZZScf3

Recently, I read two papers on lymphatic filariasis (LF) discussing Cofactor-independent phosphoglycerate mutase (iPGM) as a potential drug target for LF, published in Oxford Academy-2024 (PMID:37481257) and Bentham Publications-2023 (PMID:31244425). I'm glad to have discovered this back in 2015. Here are some insights from my original article if you're interested: https://lnkd.in/eTdnyXs3. We delved into the structural stability of Wb-iPGM through molecular dynamics simulations, shedding light on its interaction with cofactors 3-phosphoglycerate (3PGA) and Mn2+ ions. Notably, we unveiled domain motions and the catalytic significance of Mn2+ ions, offering insights crucial for drug development. #LymphaticFilariasis #DrugDiscovery #ResearchInsights #Structuralbiology #simulations #bioinformatics #computationalbiology

A new study published in Nature details a chemoproteomic workflow that allows for precise protein binding site determination of photoaffinity probes in cells. This method enables high-resolution mapping of reversible small-molecule interactions and provides a powerful tool for photoaffinity probe analysis. Learn more about this exciting development at the link below. #drugdiscovery #drugdevelopment https://lnkd.in/eMT6eQzy