Yvonne Couch’s Post

Progress with xenotransplantation for liver and kidney disease: https://lnkd.in/gVYJxHWD #liverdisease #livercancer #kidneydisease

The Composition of the Fecal and Mucosa-adherent Microbiota Varies Based on Age and Disease Activity in Ulcerative Colitis

Lupus is one of the autoimmune diseases for which Car-T holds so much promise, but stubborn barriers of cost and supply constraints have kept it from helping more patients. Cellares is one of the companies helping to break them down, as Oliver Barnes of Financial Times explores in an inspiring story on a life turned around by Car-T. https://lnkd.in/gxs7ssg4 #celltherapy

Exciting to read about a breakthrough in identifying the cause of IBD (Ulcerative Colitis and Crohn's disease)! They have discovered "a weak spot in our DNA that is present in 95% of people with the disease. It makes it much easier for some immune cells to go haywire and drive excessive inflammation in the bowels. The team have found drugs that already exist seem to reverse the disease in laboratory experiments and are now aiming for human trials." https://lnkd.in/gSK_uWMs #IBD #Crohn's #UC #UlcerativeColitis

Systemic lupus erythematosus (SLE) remains a challenging disease to control, and historically care options have been limited.     #ACR23 is a key moment to share and discuss the latest findings in lupus as we pursue our bold commitment to transform care and advance innovation to address the high remaining unmet need in this disease. Find out more about why change in lupus care is so urgently needed, and how we’re working to build a future where remission is a reality: http://bit.ly/47bZill

Identification of pyroptosis-associated genes with diagnostic value in calcific aortic valve disease Frontiers https://lnkd.in/gizBvW4d

Multiple Sclerosis, or MS, impacts millions of people worldwide as one of the most common neurological diseases. Though there is no cure for the disease, scientists are beginning to unravel one of MS’ potential causes: Epstein-Barr Virus, or EBV, a typically symptomless virus latent in more than 90% of the population that has been implicated in a variety of diseases. Read about how Wistar’s resident EBV experts Drs. Paul Lieberman and Italo Tempera are investigating the links between EBV and MS that could be a first step in preventing the development of MS in certain cases: https://lnkd.in/eTc2n2-Z - Want to know more about Wistar research? Sign up for our newsletter here: https://bit.ly/3UInm0g #MSAwarenessWeek #multiplesclerosis #epsteinbarr #research

Policy | In the First Catalogue of Rare Diseases, which was jointly developed by the National Health Commission of the PRC and five other departments in 2018, there is a rare disease called IgG4-Related Disease (IgG4-RD). As of now, clinical diagnosis of IgG4-RD relies on the following 3 aspects: https://lnkd.in/g4kD4G_v #IVD #diagnostics #raredisease #bloodtest #tumor #immunedisease #organ #tissue

Robust, Long-Term Culture of Endoderm-Derived Hepatic Organoids for Disease Modeling https://lnkd.in/eCACiNfN

Multicellular factor analysis of single-cell data for a tissue-centric understanding of disease