Explore the platform for protein and drug discovery. Innophore is a cutting-edge drug and enzyme discovery platform that uses an artificial intelligence guided point-cloud technology to identify and optimize protein candidates for various use cases. We have leading global customers in the biotech and pharmaceutical industry, including Henkel, Continental, Merck and leading companies in the field of flavours and fragrances. Our AI-driven platform, fueled by massive computing power, not only analyzes a protein’s 3D structure, but includes extended surface properties (HALOS) and volumetric cavities (catalophores), to predict its characteristics and reactivity. This puts our customers at the forefront of tackling problems in drug discovery/repurposing and opens new ways in the sustainable production of high-value compounds. Accelerate your R&D pipeline. Over the course of 20 years, protein structure database entries have grown from 13,587 to nearly a billion. This includes a recently published breakthrough database from DeepMind and the ESM Metagenomic Atlas. It is easy to get lost in the vast amount of bioinformatics information available to us today. To identify new drug candidates or enzymes based on this vast amount of data, we need to change the way we search and go beyond traditional algorithms and data types. By integrating our patented CatalophoreTM technology with a state-of-the-art conventional bioinformatics approach, as well as artificial intelligence, we are able to mine structural and sequence databases using three-dimensional (3D) search templates called “catalophores” (i.e., carrier of the catalytic function) defined by point clouds of physicochemical features. The Inventors of Catalophores. Our CatalophoreTM platform improves your wet-lab performance by minimizing the volume of in-vitro screening experiments. Our in-silico approach significantly decreases time to market and increases the probability of your success.
Externer Link zu Innophore
Am Eisernen Tor 3
c/o Humboldtstraße 50/III
Graz, 8010, AT
1700 Montgomery St
San Francisco, California 94111, US
Innophore hat dies direkt geteilt
Excited to join #GTC25 in San Jose, #SiliconValley. I'm looking forward to reconnecting with our customers, partners, and our friends at NVIDIA. It's an excellent opportunity to engage in insightful conversations, share ideas, and explore the latest innovations. See you there! The AI Factory trailer 2025 by NVIDIA and Innophore: https://lnkd.in/dXCH8kiR #GTC25 #GTC #AI #Cavitomix #drugdiscovery #enzymdiscovery #catalophore
🚀 Introducing the Human Protein Map – A Free, Open-Access Scientific Resource! 🧬🔍 We’re thrilled to launch the Human Protein Map, a powerful new tool for researchers and educators—free of charge and no registration required! 🌍 Navigate the entire human proteome with intuitive functional, structural, and target-based filters. 🔬 Compare 188,613 structural models from AlphaFold, ESMFold, OpenFold, and Homology Modeling, with PDB structures coming soon! 💊 Identify potential drug targets—explore ligand interaction data and uncover untapped possibilities. 🛠️ Analyze 400,000+ binding sites with electrostatic potential, and more! What’s the coolest or most surprising protein structure you’ve come across in your research? Let us know and get started here: https://lnkd.in/dGUSYh8k 🚀 #HumanProteinMap #Proteomics #DrugDiscovery #AI #OpenScience #Innophore
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I have officially completed my PhD! 🎉 I am incredibly grateful to Innophore and the team for the exciting opportunities, high-impact research questions, and the excellent scientific community they have provided. A special thank you to my supervisors Christian C. Gruber, Georg Steinkellner and Karl Gruber, for their invaluable guidance and support. I feel truly fortunate to have been able to learn from them! Excited for what's next 😊
I'm thrilled to congratulate Lena Parigger on graduating with her industrial PhD at Innophore! Her journey has been inspiring — a perfect blend of academic excellence at @University of Graz and innovative industrial research @Innophore. During her PhD, Lena not only deepened our understanding of AI-driven structural bioinformatics and molecular dynamics but also contributed to cutting-edge projects, such as the discovery of antivirals, our Cavitomix Copilot, optimizing variant-specific therapeutic decoys and monitoring emerging viral mutational dynamics. Lena’s work exemplifies how academic rigor paired with industry-driven solutions can accelerate drug discovery and biotechnology breakthroughs. Her contributions pave the way for more efficient, AI-powered tools in enzyme engineering, AI drug discovery, and viral variant tracking, truly impacting the field. Congratulations, Lena, on this well-deserved achievement! We can’t wait to see how your research and innovative spirit continue to drive progress at Innophore and beyond. 🧪 Statistical breakdown: Four PhD first-author papers 📰 , two PhD co-author papers 📰 and an accumulated IF of 30+ 🦾 #Congratulations #PhDGraduation #IndustrialPhD #Innovation #StructuralBioinformatics #DrugDiscovery #Innophore #GenAI #Innophore #Cavitomix #University of Graz #PhD #DrugDiscovery
Innophore hat dies direkt geteilt
I'm thrilled to congratulate Lena Parigger on graduating with her industrial PhD at Innophore! Her journey has been inspiring — a perfect blend of academic excellence at @University of Graz and innovative industrial research @Innophore. During her PhD, Lena not only deepened our understanding of AI-driven structural bioinformatics and molecular dynamics but also contributed to cutting-edge projects, such as the discovery of antivirals, our Cavitomix Copilot, optimizing variant-specific therapeutic decoys and monitoring emerging viral mutational dynamics. Lena’s work exemplifies how academic rigor paired with industry-driven solutions can accelerate drug discovery and biotechnology breakthroughs. Her contributions pave the way for more efficient, AI-powered tools in enzyme engineering, AI drug discovery, and viral variant tracking, truly impacting the field. Congratulations, Lena, on this well-deserved achievement! We can’t wait to see how your research and innovative spirit continue to drive progress at Innophore and beyond. 🧪 Statistical breakdown: Four PhD first-author papers 📰 , two PhD co-author papers 📰 and an accumulated IF of 30+ 🦾 #Congratulations #PhDGraduation #IndustrialPhD #Innovation #StructuralBioinformatics #DrugDiscovery #Innophore #GenAI #Innophore #Cavitomix #University of Graz #PhD #DrugDiscovery
Innophore hat dies direkt geteilt
I'm honored we have been invited to present Innophore's #Cavitomix Technology for #AI #offtarget prediction in the context of #kinase #drugdiscovery at the Cell Signaling Symposium 2025, held in #Vancouver 🇨🇦. This engaging and insightful event brought together 120+ leading experts from academia and industry to explore the frontiers of #cellsignaling research. With a focus on cutting-edge discoveries in kinases and their pathways — and their therapeutic potential in treating complex diseases — the symposium featured inspiring keynote speeches, dynamic panel discussions, and invaluable networking opportunities. Sharing our advancements with our new foundation model SITE-1 and connecting with passionate professionals was a pleasure. I look forward to further collaborations and innovative breakthroughs in drug discovery! Thanks to Sino Biological, Inc. / Dario P. and team for the fantastic organization and for orchestrating such a remarkable event and great talks by: - Zu-hua Gao, The University of British Columbia | #BCCancer - David Vocadlo, #SimonFraserUniversity | Alectos Therapeutics Inc. - Steven Pelech, The University of British Columbia | Kinexus - Linda Malkas, #BeckmanResearchInsitute - Xin-Yuan Fu, Sichuan University | #WestChinaHospital - Zaihui Zhang, SignalChem Lifesciences Corporation (SLC) - Hicham Zegzouti, Promega Corporation - Jason Crawford, Gandeeva Therapeutics and many more. #DrugDiscovery #CellSignaling #Innovation #Biotech #Networking #AI
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A partnership with NVIDIA has enabled Innophore to go from modeling hundreds of drug interactions per second to 5 million. In a recent conversation with Innophore CEO Christian C. Gruber, we also explored how the circa 30-person startup from Austria was highlighted by NVIDIA CEO Jensen Huang at both the J.P. Morgan Healthcare Conference and CES in January. Link to the full coverage below
Innophore hat dies direkt geteilt
🌟 Exciting news! 🌟 We are thrilled to share our latest research contribution to the field of enzyme engineering and sustainable biocatalysis! Our Innophore researchers, Bettina Nestl and Katharina Rauchenwald-Köchl, contributed to the excellent research led by Jin-Byung Park and Uwe Bornscheuer on exploring the modification of positional specificity or regioselectivity of the lipoxygenase enzyme from Pseudomonas aeruginosa (Pa-LOX). By fine-tuning the enzyme’s substrate-binding cavity through targeted mutations, PaLOX is now producing 11S-HPETE and 8S-HPETE from arachidonic acid for the first time at high conversions. 📚 Read the full paper published in ACS (American Chemical Society) Sustainable Chemistry & Engineering here: https://lnkd.in/dJtnekmm 🙏 A big thank you to our amazing collaborators, Prof. Jin-Byung Park, Prof. Uwe Bornscheuer, and their groups! #Biocatalysis #Lipoxygenase #Sustainability #Biotechnology #Oxylipins
🌟 Exciting news! 🌟 We are thrilled to share our latest research contribution to the field of enzyme engineering and sustainable biocatalysis! Our Innophore researchers, Bettina Nestl and Katharina Rauchenwald-Köchl, contributed to the excellent research led by Jin-Byung Park and Uwe Bornscheuer on exploring the modification of positional specificity or regioselectivity of the lipoxygenase enzyme from Pseudomonas aeruginosa (Pa-LOX). By fine-tuning the enzyme’s substrate-binding cavity through targeted mutations, PaLOX is now producing 11S-HPETE and 8S-HPETE from arachidonic acid for the first time at high conversions. 📚 Read the full paper published in ACS (American Chemical Society) Sustainable Chemistry & Engineering here: https://lnkd.in/dJtnekmm 🙏 A big thank you to our amazing collaborators, Prof. Jin-Byung Park, Prof. Uwe Bornscheuer, and their groups! #Biocatalysis #Lipoxygenase #Sustainability #Biotechnology #Oxylipins
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IBPRO2025 | Meet the Invited Speakers (3/8) We’re delighted to welcome Dr. Bettina Nestl as a keynote speaker at IBPRO2025! Dr. Nestl received her Ph.D. in Organic and Bioorganic Chemistry from the University of Graz, Austria, in 2007. She then pursued postdoctoral research at the The University of Manchester, UK, with Prof. Nick Turner before leading a biocatalysis research group at the University of Stuttgart, Germany. Since 2020, Dr. Nestl has been Senior Scientist and COO at Innophore, a biotech company based in Graz and San Francisco. Innophore leverages AI-driven enzyme discovery and development for applications in biotech and pharmaceuticals. Join us at IBPRO2025 to hear from Dr. Nestl and learn about the future of AI-powered biocatalysis with her talk, titled: Leveraging AI for catalophore-guided enzyme developments! #KeynoteSpeaker #IBPRO2025 #Biocatalysis #AIinBiotech #EnzymeDiscovery #ScientificInnovation #ResearchExcellence #NetworkingOpportunity