ToxMinds

At ToxMinds India, we joyfully celebrated Holi, the festival of colors, with great enthusiasm and spirit! Together, we form a beautiful harmony, each adding our unique touch. Wishing you and your loved ones a vibrant and joyful Holi! #Holi2025 #FestivalOfColors #TeamSpirit #ToxMindsIndia #JoyfulCelebrations #HoliVibes #WorkplaceCulture #HappyHoli #TeamBonding #FestiveSpirit

EU Commission presents the Clean Industrial Deal In January 2025, the Commission presented the Competitiveness Compass, a new roadmap to restore Europe’s dynamism and boost its economic growth. This roadmap builds on the analysis of Mario Draghi’s report on the future of European competitiveness and identifies a strategy for decarbonisation and competitiveness. The clean industrial deal is a direct result of this strategy. - The Clean Industrial Deal brings together climate action and competitiveness under one overarching growth strategy. - The focus will be mainly on two closely linked sectors – energy-intensive sectors (steel, metals and chemicals) and clean tech sector.  - Another key focus is circularity of the economy, which has a target of 2030. - Access to affordable energy is a cornerstone of the Clean Industrial Deal. Three key focus areas have been identified here – lowering energy bills, accelerating the roll out of clean energy and electrification and ensuring well-functioning gas markets.   Read more at:  https://lnkd.in/dqEa7CHm https://lnkd.in/eUzK7Nvu #greentechnology #decarbonisation #renewable #industrialdecarbonisationacceleratoract #cleanindustrial_deal #circulareconomy

🚨 European Commission launches evaluation of the cosmetic products regulation 🚨 The European Commission has initiated a comprehensive review of the Cosmetic Products Regulation (EC No 1223/2009) to assess its effectiveness in protecting human health, ensuring a harmonized EU market, and supporting innovation in the cosmetics industry 🔍 Call for Evidence open until 21 March 2025 As a first step, the Commission has opened a one-month Call for Evidence from 21 February to 21 March 2025 and stakeholders are invited to submit their views on the strengths, challenges, and potential gaps in the Regulation. 📌 Key areas under review: ✔ Consumer safety & ingredient risk assessment – Strengthening regulatory oversight on high-risk ingredients. ✔ Labelling & digitalization – Exploring digital labelling and refining information requirements. ✔ Market surveillance & online sales – Addressing compliance challenges in e-commerce and cross-border trade. ✔ Environmental considerations – Evaluating whether environmental impacts should be integrated into the Regulation. ✔ International competitiveness & trade – Ensuring alignment with global regulatory frameworks. ✔ Regulatory simplification – Reducing compliance burdens, particularly for SMEs. 💡 This evaluation will run from Q2 2025 to Q2 2026, with a 12-week public consultation following the Call for Evidence. 🔗 Submit your feedback here: https://lnkd.in/djcdy6xZ #RegulatoryToxicology #CosmeticsRegulation #EUcompliance #CosmeticsIndustry #Toxicology #Sustainability #DigitalLabelling #EUcosmetics #EuropeanCommision

🚀 Join Our Team – Senior Manager, Product Safety & Regulatory Compliance🚀 ToxMinds is scaling, and we need a strong product safety leader to make an impact and drive our next phase. If this resonates with you, apply directly on LinkedIn or get in touch with someone you know in our company. ✅ Lead and manage high-impact projects ✅ Mentor a talented team ✅ Work in a dynamic, collaborative environment Apply now: https://lnkd.in/gQDt6FDQ #Hiring #RegulatoryCompliance #Toxicology #ToxMinds

🚀 Join Our Team – Senior Manager, Product Safety & Regulatory Compliance🚀 ToxMinds is scaling, and we need a strong product safety leader to make an impact and drive our next phase. If this resonates with you, apply directly on LinkedIn or get in touch with someone you know in our company. ✅ Lead and manage high-impact projects ✅ Mentor a talented team ✅ Work in a dynamic, collaborative environment Apply now: https://lnkd.in/gQDt6FDQ #Hiring #RegulatoryCompliance #Toxicology #ToxMinds

📝 Draft Reflection Paper on Non-mutagenic Impurities (NMI) Qualification: Public Consultation Open 📝 The European Medicines Agency (EMA) has released a draft reflection paper for public consultation, focusing on the qualification of product-specific NMI in chemically synthesized pharmaceuticals. The paper proposes alternative strategies for qualifying NMI impurities such as the use of existing toxicological data, read-across approaches, Threshold of Toxicological Concern (TTC), computational models, and in vitro studies (E.g: Caco-2 cells and metabolism in hepatic models). Key highlights and refinements outlined in the paper include: • Determining the level of concern to decide on further actions and new route-specific TTC and dermal sensitisation threshold (DST) limits for NMI. • Calculating the Acceptable Level (AL) by incorporating additional uncertainty factors for bioavailability (F6) and addressing data gaps in toxicity data and read across (F7). • Recommendations for in vivo study design, such as using fewer animals (3/sex/group) and including toxicokinetic (TK) groups. The paper also emphasises that testing with neat, isolated impurities is preferred over spiked API batches when testing is required for NMI qualification. This consultation represents a critical opportunity for industry stakeholders to contribute to the future framework of NMI safety assessments. The deadline for submitting the comments is 30 April 2025. 📖 Read the full paper: https://lnkd.in/dzySVg-P #ICHQ3A #ICHQ3B #Pharmaceuticals #DrugDevelopment #Toxicology #RiskAssessment #EMA #Non_mutagenic_impurities #Read_across #3Rs #animal_testing #TTC #NAMs

🚨 SCCS advice on Di-n-hexyl phthalate (DnHexP) as a contaminant in UV Filter Diethylamino Hydroxybenzoyl Hexyl Benzoate (DHHB)🌞 The SCCS has assessed the presence of Di-n-hexyl phthalate (DnHexP) as a contaminant in Diethylamino Hydroxybenzoyl Hexyl Benzoate (DHHB), a widely used UV filter in cosmetic products. Given the associated health concerns, the SCCS has determined a maximum safe level of 0.026% (260 ppm) when DHHB is used up to 10% in cosmetic formulations and only if DnHexP is an unavoidable impurity. Notably, data indicate that DnHexP levels in some DHHB-containing sunscreens and sources are below the detection limit, with advanced techniques potentially reducing it to as low as 1 ppm. The SCCS recommends this 1 ppm target as the threshold for DnHexP as an unavoidable trace impurity. 🔬 Why it matters? DnHexP is a phthalate contaminant associated with health concerns, making strict impurity control essential in cosmetic safety assessments. 📢 Regulatory implications: This recommendation may impact manufacturers and suppliers of UV filters, and improved purification processes for safer sunscreen formulations. Full SCCS opinion read here: https://lnkd.in/dnmD4YaS #CosmeticSafety #SCCS #UVFilters #DHHB #Phthalates #CosmeticRegulations #PersonalCare

🚨 EMA Releases Revised Draft Reflection Paper on Non-Animal Testing Methods 🚨 The European Medicines Agency (EMA) has issued a revised draft reflection paper outlining non-animal replacement tests for pharmaceutical development, reinforcing global efforts to advance 3Rs principles (Replacement, Reduction, Refinement). This updated paper, which replaces the 2018 version, provides guidance on regulatory acceptance of animal-free testing alternatives across various EMA committees, including CHMP, CVMP, and the European Pharmacopoeia. Key highlights include: ✅ Adoption of Recombinant Factor C (rFC) as an alternative to horseshoe crab blood for endotoxin testing ✅ Endorsement of the Monocyte Activation Test (MAT) to replace the rabbit pyrogen test ✅ Elimination of certain rodent-based studies for radiopharmaceuticals   📢 The deadline for public comments is 30 June 2025. It is critical news in Pharma testing! Industry stakeholders are encouraged to review and contribute to this important discussion. 🔗 Read more: https://lnkd.in/gCRh_iwN #Pharma #EMA #3Rs #RegulatoryScience #PharmaInnovation #AnimalTesting #DrugDevelopment #EthicalScience #RegulatoryAffairs

🌟 Celebrating Women in Science Day! 🔬👩🔬 Today, we honor the incredible women in science who drive innovation, push boundaries, and make a lasting impact on the world. In toxicology, their expertise, dedication, and passion are essential in protecting health and the environment. At ToxMinds, we are proud to have an amazing team of female scientists whose contributions shape the future of our field. Your knowledge, commitment, and leadership inspire us every day! 💙 Thank you for your hard work and for making science stronger! 📸 Here’s to the women in our team—brilliant minds making a difference! #WomenInScience #Toxicology #STEM #WomenInSTEM #WomenInScience #ScienceMatters #Teamwork #Innovation #ToxMindsTeam

Brussels x Bangalore: One Team, One Vision Thomas Petry, Ph.D. and Marvin Pottier had an amazing time visiting our team led by its director Sanghamitra Mishra, ERT in Bangalore. It wasn’t just about meetings, it was about real connections, great conversations, and sharing the energy that makes ToxMinds unique. Excellence is one of our purposes, we’ve grown into a truly global team, now 50/50 between Brussels and Bangalore. It’s one, seamless, connected, and driven by the same goals team, no matter where we are. This picture perfectly captures collaboration, laughter, and the team spirit you can’t fake. We're proud of how far we’ve come, and even more excited about where we’re heading together!