Vésale Bioscience

This milestone study published in Nature on life-threatening infections has provided invaluable insights and demonstrated the safety and efficacy of personalized phage therapy as a promising strategy to battle difficult-to-treat infections. • Retrospective analysis of 100 consecutive cases, facilitated by a Belgian consortium across 35 hospitals, 29 cities, and 12 countries • Clinical Improvement: 77.2% of infections showed clinical improvement • Bacterial Eradication: Targeted bacteria were eradicated in 61.3% of cases • Combination Therapy: Therapy was more effective with antibiotics, showing a 70% lower eradication rate without their use • Tailored Treatment: Susceptibility tests ensured the chosen phages were effective against the specific bacterial pathogens infecting each patient Congratulations to Jean-Paul Pirnay and Sarah Djebara  of the Queen Astrid Military Hospital in Belgium, and the entire collaborating team for their exceptional work in highlighting the power of personalized phage therapy! #phage #phagetherapy #antibioticresistance #infectiousdiseases #AMR https://lnkd.in/e8ixuFq7

This milestone study published in Nature on life-threatening infections has provided invaluable insights and demonstrated the safety and efficacy of personalized phage therapy as a promising strategy to battle difficult-to-treat infections. • Retrospective analysis of 100 consecutive cases, facilitated by a Belgian consortium across 35 hospitals, 29 cities, and 12 countries • Clinical Improvement: 77.2% of infections showed clinical improvement • Bacterial Eradication: Targeted bacteria were eradicated in 61.3% of cases • Combination Therapy: Therapy was more effective with antibiotics, showing a 70% lower eradication rate without their use • Tailored Treatment: Susceptibility tests ensured the chosen phages were effective against the specific bacterial pathogens infecting each patient Congratulations to Jean-Paul Pirnay and Sarah Djebara  of the Queen Astrid Military Hospital in Belgium, and the entire collaborating team for their exceptional work in highlighting the power of personalized phage therapy! #phage #phagetherapy #antibioticresistance #infectiousdiseases #AMR https://lnkd.in/e8ixuFq7

Exciting News We are thrilled to share a significant milestone in the world of Phage Therapy. The eagerly awaited new General Chapter in the European Pharmacopoeia on Phage Therapy Medicinal Products (PTMPs) has appeared. This is the first-ever official text providing a comprehensive framework of requirements for the production and control of PTMPs published in a pharmacopeia.  “Phage therapy medicinal products (PTMPs) are preparations of naturally occurring or genetically modified phages used to treat or prevent human or veterinary bacterial infections. A PTMP can contain one phage, i.e. a single phage therapy active substance, or a mixture of phages, combined with excipients. PTMPs can be administered by various routes and are available in different dosage forms.” The new general chapter on Phage Therapy Medicinal Products has been adopted and exceptionally pre-published (see link in comments) in advance of its formal publication in July due to the high public interest. We extend our gratitude to all those involved in this collaborative effort, paving the way for the advancement of phage therapy and its potential to revolutionize infectious disease treatment. Stay tuned for more updates. #PhageTherapy #AMR #Bacteriophage

🌟 We're Expanding Our Team: Executive Assistant at Vésale Bioscience 🌟 At Vésale Bioscience, a leader in the biotech and medtech innovation space, we are on the lookout for a dedicated and proficient Executive Assistant to provide vital support to our executive team. This role is perfect for someone who thrives in a fast-paced environment, possesses impeccable organizational skills, and has a keen interest in the biotech and medtech sectors. Ready to make an impact? Learn more about the position and apply here: https://lnkd.in/e3VR-SxB

The BSM "Expert Seminar" on the 7th of March : an amazing afternoon to hear from experts discussing innovative approaches to combat multi-drug resistant bacteria.#BSM #PhageTherapy,#antibiotic #AMR #EU2024BE https://lnkd.in/e9XYk9kV

#Vésale Bioscience couldn’t miss the 8th edition of the #AMRconference, organized in BASEL (Switzerland) next March 6&7 as this event will pay attention to and cover the latest trends in the development of AMR products and therapy with specific sessions dedicated to #phagetherapy. There will also be a special focus on #onehealth and on how artificial intelligence can foster prevention and smart use to face AMR. The #AMRconference is a platform for SMEs, start-ups, big pharma, academia, investors, and public institutions to discuss strategies and specific challenges faced by the innovation ecosystem in bringing new antimicrobial treatments and diagnostics to the market. #phage, #bacteria, #medicine, #research, #healthcare, #AMR, #phagetherapy, #bacteriophages, #bacterialinfections, AMR Conference – Novel Antimicrobials & AMR Diagnostics (amr-conference.com)

Physicians are increasingly interested in using phages to combat infections that are multi-resistant to current therapeutic treatments. A team from the University of Pittsburgh is attempting to "combine these phages with antibiotics". "In the journal mBio, these bacteriologists and infectiologists present a new case study of a drug-resistant bacterium responding to combined phage-antibiotic therapy." https://lnkd.in/eNefnK2v

An excellent initiative from the Belgian Society for Viruses and Microbes, of which we are a partner. BVSoM is launching the winter edition of the "My Hero and Me" webinar series, in which a young scientist and his or her hero give a joint webinar on their topic of interest. Inspiring early-career scientists is not only a good idea and a good spirit; in the face of one of this century's most critical health challenges, it's also a necessity. “Drivers and consequences of bacteriophage host range from an eco-evolutionary perspective” is the thema of this winter edition that will be organized on Thursday February 15, 2024, at 4:30 – 5:30 pm ((GMT+1:00) Brussels) via Zoom (More information and registration : https://lnkd.in/e-p3bWHS #phagetherapy #BVSoM #phage, #bacteria, #medicine, #research, #healthcare, #AMR, #Vésale Bioscience

"Last Chance to Save a Life" : an excellent and captivating independent documentary exploring innovative new therapies to combat drug-resistant infections. We're delighted to discover that the Belgian model is being followed by Australia. The full documentary will be broadcast on February 15. Here's the link to a sneak preview of the documentary trailer https://lnkd.in/e_kw_iTi #AMR #Phage #phagetherapy

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