Evotec

PanHunter provides multiple interactive analyses for scientists looking to gain deeper insights into their projects. Do you want to know which biological pathways and gene sets are significantly regulated by your treatment? Which proteins physically interact with your target? Are there other treatments or diseases that induce regulation similar to yours? Find out how PanHunter answers these questions! https://hubs.ly/Q02Mv9L10 #researchneverstops #panhunter #omics #transcriptomics #proteomics #dataanalysis #datascience

Missed our live webinars on “Mastering Quality by Design”? Catch up on-demand! Evotec’s Quality by Design webinar series is now available to stream on-demand. Dive into the sessions at your convenience and gain valuable insights into QbD’s role in enhancing pharmaceutical quality. https://hubs.ly/Q02LpDCw0. #drugdevelopment #QualityByDesign

Unlocking GPCR Secrets with GCI... Dr. Edoardo Fabini, our Biophysics lead, will reveal how GCI is revolutionizing small molecule studies and how this impacts fragment screening & GPCR drug discovery. Where? At the GCI/ITC EMEA Community Meeting, organised by Malvern Panalytical. Find everything you need to know here: https://hubs.ly/Q02N07vC0 See you there! #MembraneProteins #GCI #GPCR

Speed up your drug discovery with Cyprotex! Our high throughput ADME services deliver rapid & reliable data for you to make informed decisions quickly. Reach out to us to find out more about our customizable protocols, industry-validated methods, ADME consultancy service, and < 72 hr turnaround for key assays on your regular screening contracts at enquiries@cyprotex.com Learn more: https://hubs.ly/Q02M_Q6V0 #researchneverstops #adme #cyprotex

Read our new blog article and learn more about Evotec's end-to-end capabilities for the synthesis, purification, isolation, and quality control of complex modified Oligonucleotides, such as ASOs and siRNAs. We can support Oligonucleotide drug discovery and development projects from the earliest phases of discovery, such as the generation of screening libraries, up to the selection of a preclinical development candidate followed by manufacture and release of material to support initial preclinical development studies. Learn more in our recent blog article- https://hubs.ly/Q02Kch2C0

Join us us at the EFMC International Symposium on Medicinal Chemistry in Rome next week! Mafalda Pagano, our medicinal chemistry expert, will be presenting a poster on Application of early dose to man calculations to guide the selection of a selective tool compound for probing the role of lysophosphatidic acid type 2 receptor antagonists in idiopathic pulmonary fibrosis on on Monday, 2 September from 17:30 to 19:00. Fabrizio Micheli, VP Medicinal Chemistry, will be attending as part of the local organizing committee. Learn more about the event and contact us to arrange a meeting here- https://hubs.ly/Q02MRHBZ0 #MedicinalChemistry #EFMC-ISMC2024

Missed our live webinar on case study ID11916? Catch up on demand! Discover how a poorly soluble drug was turned into a high-performing formulation in just six weeks, even with scarce API availability. Our experts, Fabrizio Fina and Zsolt Lendvai, present the fascinating case study of ID11916. They explain how they transformed its initial water-insoluble state into an innovative oral formulation, accelerating its path to the human clinical trial phase. Don't miss out on this insightful session! https://hubs.ly/Q02Kch-B0 #bioavailability #preformulation #earlyformulation #drugdevelopment

Join Us at Eurotox 2024! We are thrilled to invite you to two exciting events hosted by Evotec and Cyprotex at Eurotox 2024! Don't miss these opportunities to gain valuable insights and network with industry experts. Industry Hosted Session Topic: Navigating the Preclinical Development of Antibody Drug Conjugates (ADCs) Focus: Toxicology De-Risking Strategies for Enabling Personalized Medicine Date & Time: Monday, 9 September 2024, 12:00-13:00 Presenters: Dario Salerno, Senior Manager, Safety Assessment, and Giulia Iannoto, Immunotoxicologist, Safety Assessment Session Highlights: - Explore the complexities of ADCs, biopharmaceutical molecules designed to target cancer cells. - Understand the unique challenges in nonclinical safety assessment of ADCs. - Learn about the science-based approach to safety assessment and current regulatory guidelines. - Discover our recent case study and experiences with ADCs. Poster Presentation Title: Multiparametric In Vitro Assays Combined with High-Throughput RNA Sequencing for Cardiotoxicity Risk Assessment and Mechanistic Insight (#916) Date and time: Monday, 9 September 2024, 9:30am Presenter: Samantha Llewellyn, Associate Principal Scientist - Cyprotex Join us to delve into innovative methodologies for cardiotoxicity risk assessment and gain mechanistic insights through high-throughput RNA sequencing. Don't miss these sessions to stay at the forefront of toxicology and preclinical development. We look forward to seeing you there! #Eurotox2024 #ADCs #Toxicology #PreclinicalDevelopment #Cardiotoxicity #PersonalizedMedicine https://hubs.ly/Q02L3WNC0

Accelerating Chemistry Innovation: Evotec's High Throughput Experimentation (HTE) Platform in Drug Discovery and Development - This will be the topic of our presentation at ChemOutsourcing 2024 in Parsippany, NJ, in September. Zadeo Cimarosti, our Head of API Development & Industrialization, will be presenting. Our team will be at booth #72 if you wish to learn more about our chemistry capabilities in drug discovery and drug development. We hope to see you there! Learn more about the event here- https://hubs.ly/Q02KbPVW0

Navigating the Complexities of Cell-Based Therapies: Join Our VP at ISCT Europe 2024! The world of cell-based therapies is rapidly evolving, and regulatory challenges are at the forefront. Join our VP of ATMP Global Regulatory Affairs, Michela Gabaldo, as she chairs a crucial session on ATMP Regulatory Interplay at the upcoming ISCT Europe 2024 in Gothenburg! Why attend? - Gain insights into the difficulties in navigating quality and regulatory standards for cell-based starting materials. - Understand how to balance regulatory resilience and harmonization in this exciting field. Session Details: Date: Thursday, September 5th Time: 13:45 - 14:45 CET Interested in learning more about iPSC-based cell therapy or connecting with Michela? Contact us at info@evotec.com #ISCTEurope2024 #CellTherapy #ATMP #RegulatoryAffairs #iPSC