Nuvisan

🎉 We are proud of being part of IN-ARMOR project!   IN-ARMOR is a project funded by the European Health and Digital Executive Agency (HADEA). Its goal is to optimize therapeutic epigenetic enhancement of innate immunity to effectively combat antimicrobial resistance (AMR). The primary objective of IN-ARMOR is to refine the structure and function of a novel family of compounds known as Aroylated Phenylenediamines (APD). This will be achieved using in silico solutions and computer molecular analysis, alongside a nanotechnology-based drug delivery system, to validate their safety and efficacy.   Collaborating with leading professors, researchers, and industry partners, NUVISAN supports the process development of clinical candidates. To this end, NUVISAN will perform route scouting, polymorph screening, and develop analytical methods to support the kilogram-scale manufacture of the drug substance.   🤝 Together, we will make groundbreaking strides in infectious disease research! For the full news-> https://lnkd.in/e2F7ygiD Take a look at NUVISAN’s chemical development expertise-> https://lnkd.in/ek7j3XBY   #NUVISAN #InArmorProject #EuropeanProjects #AMR #ScienceCRO  

💡 Embracing Creativity and Innovation At NUVISAN, we understand that experience and expertise alone aren't enough to bring therapies to patients. That’s why we’re dedicated to thinking creatively and fostering a culture of openness and innovation. Our commitment to innovation extends beyond our science, even to the little things—like our latest marketing giveaway. We've teamed up with a creative popcorn maker in Berlin who crafts unique and imaginative popcorn flavors. 🌟 Pop by our NUVISAN booth at the upcoming DMDG conference in York, UK on September 2-4 and grab your taste of science. 📅 Schedule a meeting with our NUVISAN delegates-> https://lnkd.in/e4ndtTkQ Our colleagues, Piet S., Stephanie Urschel PhD., Olivier Baverey and Alexander Aslanidis, PhD look forward to meeting you! #innovation #ScienceCRO #DMPK #DMDG #NUVISAN

🌟 NUVISAN is going to attend the EFMC-ISMC 2024 🌟 From September 1-5, our NUVISAN experts, Franz von Nussbaum, Juliette Pabst, Kai Thede Steffen Gressies Stefan Werner from the drug discovery division will be at the EFMC-ISMC 2024, one of the leading Medicinal Chemistry and Chemical Biology meetings worldwide in Rome, Italy. Join us to explore the latest technologies, trends and breakthroughs in chemical biology and drug discovery projects. Our team of experts will be on-site, ready to discuss your chemical matters and answer any questions you may have. 👨🔬 Visit Our Booth: Learn about our cutting-edge services and how we can support you in turning your hit molecule into a drug. 🔬 View our Posters: Enjoy some scientific discussion with our scientists. 🤝 Meet our Experts: Discover opportunities for collaboration and brainstorm innovative solutions together. We look forward to seeing you there! Schedule a meeting-> https://lnkd.in/excR7WYi #NUVISAN #EFMCISMC2024 #MedicinalChemistry #ChemicalBiology #Innovation #ScienceCRO

🌟Meet us at the DMDG 🌟 We are excited to announce our participation in the DMDG 50th Open Meeting 2024, taking place from September 2-4 at the University of York, UK Join us as we engage with scientists to explore the latest advancements in drug metabolism and pharmacokinetics. Our team, Piet S. Stephanie Urschel PhD. Alexander Aslanidis, PhD Olivier Baverey will be on hand to share insights, discuss innovative solutions for your unique projects. 🤝 Don't miss this opportunity to connect with us and explore how NUVISAN can facilitate your research and development successes. 📰 In addition to visiting the NUVISAN booth, we invite you to check out our poster and attend our presentation by Piet S., our Head of DMPK and Toxicology. Join us on Tuesday, September 3rd, during Session 8, to gain valuable insights on how we have supported a complex metabolism project in human. We hope to see you there! Schedule a meeting with us NOW-> https://lnkd.in/e4ndtTkQ #NUVISAN #DMDG50 #DMPK #DrugDevelopment #DrugDiscovery #ScienceCRO

🚀 Discover Innovative Drug Discovery Approach! Optimizing molecules for drug discovery is often a tedious and costly process. However, by implementing automation and miniaturization directly into biological assays, we can accelerate synthesis, save expensive reagents, and eliminate the need for extensive single-compound purification and handling. This innovative approach is commonly known as plate-based chemistry or direct-to-biology. In addition to classical small molecules, this method has been successfully applied to new modalities like PROTACs. At the upcoming EFMC-ISMC 2024, where we will showcase a proof-of-principle case study demonstrating automated reaction miniaturization of amide couplings, followed by direct biological readouts of unpurified reaction mixtures. 🌐Curious about the details? Visit our poster and schedule a meeting with our team for an in-depth discussion -> https://lnkd.in/excR7WYi #PlateBasedChemistry #LifeScienceChemistry #DrugDiscovery #EFMCISMC2024 #NUVISAN #ScienceCRO

🌟New Flyer Alert! High-throughput Screening for Mechanism-based Inhibition of CYP3A4 (HTS-MBI) Drugs that cause irreversible, mechanism-based inhibition of CYP3A4 are highly likely to lead to drug-drug interactions with commonly used therapeutics, many of which are also metabolized by CYP3A4. By selecting a candidate drug that does not inactivate CYP3A4, you can reduce the need for extensive risk assessments of drug-drug interactions during the clinical phase. At NUVISAN, we perform a concentration- and time-dependent inhibition screening of your drug candidate library, giving you clarity on the structure-activity relationship with respect to potential irreversible CYP3A4 inhibition. To remove safety liabilities for your drug in development, we help you during your lead optimization phase by screening individual compounds or entire NCE libraries Would you like to know more about this topic? please visit -> https://lnkd.in/ePuQpEYu or contact Dirk Scharn 🚀 Choose the right compound early to set the stage for success in drug development #DDI #HighThroughPutScreening #CYP3A4 #DrugDevelopment #NUVISAN #ScienceCRO

🚀 Exciting News! Our Microbiological Chemistry & Metabolite Discovery Flyer has landed! With over 60 years of experience in biotransformations within pharmaceutical and agricultural settings, we excel in producing drug metabolites, conducting preparative-scale biotransformations, and efficiently upscaling proteins and plasmids by leveraging nature’s rich toolbox. NUVISAN’s expertise in microbiological chemistry & Metabolite Discovery, in a nutshell: • Proprietary biotransformation approaches for mg to gram scale metabolite generation • Complex synthetic chemistry and hybrid approaches via late-stage diversification • Isotope chemistry & process development to make labeled drug metabolites • State-of-the-art analytics for purification, structural elucidation and characterisation 🌐 Curious to learn more? Check out our flyer: https://lnkd.in/efBe--Qc or contact our expert Kai Thede #biotransformation #bioreactors #chemistry #DrugDiscovery #NUVISAN

🚀 Exciting News from NUVISAN! 🚀 We are thrilled to announce the launch of our refreshed NUVISAN career webpage!   Our career page is designed to provide a seamless experience for job seekers and offers a glimpse into the innovative and dynamic environment at NUVISAN. Whether you are looking for an opportunity to start your career or to bring your expertise to a new team, we have a variety of roles across multiple disciplines waiting for you.   🔍 Explore Our Opportunities: Discover the diverse range of positions available at NUVISAN. Find out what it's like to work with us and explore the corporate benefits we offer.   We are always looking for talented and passionate individuals to join our team. Visit our career page today to learn more about how you can join our exciting journey! 👉 https://lnkd.in/eZbhgHDP   💪 Thanks to the dedicated HR team for working together on this project!   #NUVISAN #CareerOpportunities #Innovation #DrugDiscovery #DrugDevelopment   __   🚀 Spannende Neuigkeiten von NUVISAN! 🚀 Wir freuen uns, dir den Start unserer überarbeiteten NUVISAN-Karriereseite bekannt zu geben! Unsere Karriereseite bietet dir eine nahtlose Erfahrung und einen Einblick in das innovative und dynamische Umfeld bei NUVISAN. Ob du deine Karriere beginnen oder deine Expertise in ein neues Team einbringen möchtest, wir haben eine Vielzahl von Positionen in verschiedenen Disziplinen für dich. 🔍 Entdecke deine Möglichkeiten: Erkunde die vielfältigen Positionen, die bei NUVISAN verfügbar sind. Erfahre, wie es ist, bei uns zu arbeiten und welche Vorteile wir bieten. Wir sind immer auf der Suche nach talentierten und leidenschaftlichen Persönlichkeiten, die unser Team verstärken möchten. Besuche noch heute unsere Karriereseite und erfahre mehr darüber, wie du Teil unserer spannenden Reise werden kannst! 👉 https://lnkd.in/eZbhgHDP Vielen Dank an das engagierte HR-Team für die hervorragende Zusammenarbeit an diesem Projekt! #NUVISAN #Karrieremöglichkeiten #Innovation #Arzneimittelforschung #Arzneimittelentwicklung

🚀 Exciting News! Our In Vitro Discovery DMPK Flyer has landed! At NUVISAN, we're committed to providing exceptional DMPK (drug metabolism and pharmacokinetics) services. Our preclinical compound profiling spans the entire ADME spectrum—Absorption, Distribution, Metabolism, and Excretion—to guide your project towards viable clinical drug candidates. With decades of pharma expertise, our dedicated NUVISAN scientists support you every step of the way—from assay design to interpreting results and implementing screening strategies. We're here to help you overcome ADME liabilities and mitigate DDI (Drug-drug interaction) risks. 🌐 Curious to learn more? Check out our flyer-> https://lnkd.in/eTv2wYUN and discover how NUVISAN can elevate your drug discovery journey #DMPK #DrugDevelopment #DrugDiscovery #NUVISAN #Innovation #ADME

🎉 Award at Jugend forscht! 🎉 We are proud to announce that NUVISAN has been recognized at Jugend forscht for its outstanding project, Black “gold” from mushrooms – melanin extraction from Armillaria mellea . This prestigious recognition is a testament to our unwavering dedication to fostering future talents in the fields of science, technology, engineering, and mathematics (STEM). In this project, our Microbiological chemistry department collaborated with young talent to establish a protocol for cultivating fungi in shake flasks. His aim was to find the conditions that produce the highest yield of melanin by varying the ingredients of culture media and to conduct first purification steps of melanin. We are thrilled to see that the process we developed generates a melanin yield approximately 1000 times higher than that obtained with conventional methods, such as melanin extraction from octopuses. 💡 We are excited about the future and dedicated to fostering scientific exploration and technological advancement. 📰 For the full news article->  https://lnkd.in/gsRTVihH 🔬 For more information about our Microbiological chemistry solution-> https://lnkd.in/gJHvx2xn 💬 If you are interested in the details about the project, please contact Jakob Wagner Kai Thede #NUVISAN #MicrobiologicalChemistry #JugendForscht #Melanin #STEM