PromoCell - Human Centered Science

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From 3D organoids to air-liquid interface cultures and “lung-on-chip” devices, each in vitro lung model offers unique insights into different aspects of lung function. Read our blog post to discover the intricacies and possibilities of the various types of in vitro lung models and how to select the right one for your research: https://hubs.li/Q02SWjTP0 #respiratoryresearch #biomedicalresearch

How is regenerative medicine revolutionizing dermatology? Dermatology experts reveal how innovative technologies like CRISPR/Cas9 and 3D bioprinting are accelerating progress in skin therapies. Find out more in our interview with RegMedNet: https://lnkd.in/e8YPyRi8 #dermatology #cellculture

In vitro studies are crucial for the development of new treatments. From high-throughput drug screening to personalized medicine approaches, these studies are accelerating the development of obesity treatments that go beyond weight loss. However, in vitro obesity research also faces challenges, like replicating the complex environment of adipose tissue and accounting for individual variability in adipose cell behavior. Learn more about the potentials and challenges of in vitro obesity research in our blog post: https://hubs.li/Q02Pj3M70 #obesityresearch #obesity #research #cellculture

Curious about the promise of in vitro lung models for respiratory research? In our latest blog post, we dive into the mechanics and different types of in vitro lung models and discuss their crucial role in our understanding of lung diseases. Read our blog post to stay at the forefront of lung model innovation and how they can transform respiratory research: https://lnkd.in/e-Yc_Qrt #biomedicalresearch #respiratoryresearch

How can ALI shape the future of diagnostics and treatments? In an insightful interview with RegMedNet our experts discuss the potential of ALI models in establishing complex triculture systems, advanced disease models, and personalized therapies. Read the full interview: https://hubs.li/Q02S1tRD0

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Aging is a natural process characterized by a gradual decline in our physiological systems. Over time, our cells lose their ability to proliferate, differentiate, and repair, resulting in sustained wear and reduced organ performance. In a recent study, scientists at the David Geffen School of Medicine at UCLA and the University of Helsinki joined forces to investigate the relationship between age and obesity. The team integrated bulk and single-nucleus RNA sequencing data from subcutaneous adipose tissue (SAT) with genotyping data from the UK Biobank. They focused on age-obesity interactions originating from adipose stem and progenitor cells (ASPCs). Through comprehensive analyses, they discovered that obesity prematurely reduces the proportion of ASPCs. The team also identified 76 ASPC genes that are deregulated during aging, shedding light on the cellular and genetic interactions that regulate fat cell differentiation and link aging to obesity. This research highlights that understanding the complex interplay between aging and obesity may help us identify interventions to address obesity and improve overall health as we age. Asha K., A., Alvarez, M., Garske, K.M. et al. Age-dependent genes in adipose stem and precursor cells affect regulation of fat cell differentiation and link aging to obesity via cellular and genetic interactions. Genome Med 16, 19 (2024). https://lnkd.in/ejJdiFzP #cellculture #agingresearch #obesityresearch

RegMedNet interviewed leading experts about the latest advancements in regenerative medicine in dermatology. Discover how new technologies and approaches are transforming skin treatment and wound healing. Are you ready to explore the future of skin care? Read the full interview on RegMedNet: https://lnkd.in/e8YPyRi8 #dermatology #cellculture Eva Morgenstern

Facing challenges in MSC characterization? In our blog post, we discuss the complexities of MSC characterization — from population heterogeneity to variations in isolation methods. We also offer solutions for standardized protocols to help you navigate MSC characterization hurdles. Enhance MSC standardization with expert insights: https://lnkd.in/gHtTfs53 #stemcells #cellculture