Nexotech_New_Exosomes

"𝐀𝐧 𝐞𝐱𝐩𝐥𝐨𝐫𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐬𝐦𝐚𝐥𝐥 𝐞𝐱𝐭𝐫𝐚𝐜𝐞𝐥𝐥𝐮𝐥𝐚𝐫 𝐯𝐞𝐬𝐢𝐜𝐥𝐞 𝐧𝐮𝐜𝐥𝐞𝐢𝐜 𝐚𝐜𝐢𝐝 𝐜𝐚𝐫𝐠𝐨 𝐚𝐬 𝐚 𝐥𝐢𝐪𝐮𝐢𝐝 𝐛𝐢𝐨𝐩𝐬𝐲 𝐚𝐧𝐚𝐥𝐲𝐭𝐞 𝐟𝐨𝐫 𝐛𝐫𝐞𝐚𝐬𝐭 𝐜𝐚𝐧𝐜𝐞𝐫", by Tumisang Philile Ntereke. The aim of this #thesis was to compare methods for the #isolation of sEVs from limited blood plasma volumes and to explore their #DNA and #RNA cargo in comparison with circulating tumour DNA (ctDNA) towards developing a multi-analyte #LiquidBiopsy (MALBA) test. Our kit #exoGAG was screened using sEVs from in vitro cell culture models. In conclusion, results presented in the thesis show that sEVs harbour DNA and RNA cargo and can provide additional information to plasma cfDNA warranting further investigation of sEV cargo as a liquid biopsy analyte in a larger series of patients. https://lnkd.in/dKjQxKyp

"𝐃𝐞𝐯𝐞𝐥𝐨𝐩𝐦𝐞𝐧𝐭 𝐨𝐟 𝐚 𝐦𝐢𝐜𝐫𝐨𝐟𝐥𝐮𝐢𝐝𝐢𝐜 𝐝𝐞𝐯𝐢𝐜𝐞 𝐟𝐨𝐫 𝐭𝐡𝐞 𝐢𝐬𝐨𝐥𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐭𝐮𝐦𝐨𝐮𝐫 -𝐝𝐞𝐫𝐢𝐯𝐞𝐝 𝐞𝐱𝐭𝐫𝐚𝐜𝐞𝐥𝐥𝐮𝐥𝐚𝐫 𝐯𝐞𝐬𝐢𝐜𝐥𝐞𝐬" Today we share this paper from a project in which #ExoGAG was used. By José Luís de Faria and Silva Matos Paiva. #BreastCancer has been a recurring condition that affects, especially, the health of many women worldwide. Even though modern technology has been able to monitor these patients and apply treatment, reducing the mortality rate, early diagnosis still lags, resulting in an overall cause of morbidity induced by #cancer #metastasis. "One of the biggest challenges for the study of Extracellular vesicles (EVs) has been their isolation. Current techniques are generally time-consuming and also inherently provide a low yield. Recently, the #ExoGAG reagent has been introduced as an alternative method to streamline EV enrichment allowing their isolation from #LiquidBiopsies, and obtaining a purified EV population.  This project aims to develop a microfluidic device capable of mixing EVs with ExoGAG to obtain a purified sample for breast cancer diagnosis." Don't miss all the details of this interesting project! 👉 https://lnkd.in/dMCjZjEQ 👈

#Nexotech is pleased to announce the new partnership agreement signed with Nucleus Biotech GmbH to boost the distribution of ExoGAG in Germany, Switzerland, and Austria! We are excited to partner with #NucleusBiotech, a German company renowned for its expertise in providing cutting-edge reagents and services to the scientific community. We believe this collaboration will enable more researchers to access the innovative solutions we offer. #ExoGAG is a product that allows the isolation of #exosomes for #biomarker research, which could help oncologists to diagnose and monitor their patients by #LiquidBiopsy. This agreement marks a significant milestone in the expansion of ExoGAG's presence in the European market, offering #researchers a powerful tool to advance their studies and discoveries in the field of cell and molecular biology. #Research #Oncology #Health AMSlab | NASASBIOTECH SL https://lnkd.in/d6DxjWC2

"Determinar el mejor #tratamiento para cada #paciente a partir del análisis de #biomarcadores de una muestra de sangre. Este es, hoy por hoy, el principal uso de la #BiopsiaLíquida, una de las estrategias clave en la #oncología de predicción y que apenas asoma su enorme potencial." También puede emplearse para predecir la recurrencia o no de un #tumor y evitar así la administración de #quimioterapia de forma innecesaria. Y, dentro de no mucho, podrá usarse de forma rutinaria para la detección precoz de los tumores. Sin embargo, el análisis de biomarcadores en la sangre para elegir terapias personalizadas para el #cáncer solo se emplea en el 15% de los pacientes. Es fundamental que tanto profesionales de la #salud como la sociedad en general tomemos conciencia de la importancia de esta tecnología. El avance en la #investigación y la implementación de la biopsia líquida puede cambiar el paradigma en el cuidado de la salud, llevándonos hacia un enfoque más personalizado y eficaz. #BiopsiaLíquida #Salud #InnovaciónMédica #InvestigaciónMédica #Cáncer #SaludPública - NASASBIOTECH SL https://lnkd.in/dEuN7Cqs

🌐 Today we are pleased to announce that our new website is now available! A website in which we wanted to simplify as much as possible to focus on what is important: how we can help you. We invite you to take a look at it and to contact us for any matter you need. https://lnkd.in/d96V6nt9 NASASBIOTECH SL & AMSlab #Exosomes #ClinicalSector #Health #Research #ExoGag #Hospital