BiACEM

Georgios Theodoridis from Aristotle University of Thessaloniki, Greece presented a talk entitled "Analyte Identification in Untargeted Analysis: Chromatography Matters" at #ISC2024 which discussed the challenges of analyte identification in untargeted analysis, highlighting its significance in metabolomics and non-target screening. Theodoridis highlighted the identification process is often prone to errors, requiring skilled researchers and robust IT tools, which may not always be available, and leads to critical mistakes, according to Theodoridis, and especially with liquid chromatography–mass spectrometry. Accurate identification is vital he stressed, because errors can invalidate biochemical interpretations and hinder biomarker discovery. He highlighted two common error types —biologically implausible identities and those inconsistent with chromatographic data — and proposed measures to enhance the situation, particularly by raising awareness of the problem and effective use of chromatographic data.

Presenting the findings of the work "Determination of short chain fatty acids in human fecal samples by GC-MS" in the frame of the International Symposium on Chromatography 2024, Liverpool, UK, 6-10 October 2024

Georgios Theodoridis, BiACEM PI presented at the International Symposium on Chromatography 2024, discussing the need for chromatographic data and its added value in the workflow for metabolite identification (MetID) in untargeted #metabolomics. The aim is to raise awareness on erroneous identification. Major bottleneck in metabolomics, MetID remains a time consuming and error prone step. Nevertheless, it is VERY important; if MetID is wrong, any generated biochemical pathway analysis is void. More details in our perspective article https://lnkd.in/dJRX7zsu new report in on the making #chromatography, #analyticalchemistry, #massspectrometry

Today we hosted Dr. George Kaklamanos, Senior Scientist at the Organisation for the Prohibition of Chemical Weapons (OPCW). George, one of the first PhD students of our team, spent years at IRMM Joint Research Centre, Geel and Wageningen RIKILT, working on #LCMS and #IRMS technology for #foodauthenticity and the labs of the Greek Ministry of Agriculture, before joining OPCW. He discussed with our scientists on sotware tools for peak picking and deconvolution of HRMS data from #untargetedanalysis. In the photo with Theano Rizou, Ifigeneia Rizopoulou and Georgios Theodoridis #toxicology, #biomarkers, #publichealth

Busy night yesterday at the researchers night at the Music Concert Thessaloniki. Families, young children, fellow scientists paid a visit to the booth of the BIOMIC_AUTh Laboratory of the Aristotle University of Thessaloniki (AUTH). Many thanks to the members of our team, which in the 6 hour event presented to our visitors our EU funded research projects BiACEM, CoDiet, HUMAN Doctoral Network in Metabolomics Research, ProxIMed, FunTomP. Olga Begou Danai Rossiou Ifigeneia Rizopoulou Alexandra Tiganouria Marlene Thaitumu, PhD Candidate (M.S.Curie Fellow) Aristea Papaioannou Vasiliki Gkanali Christina Virgiliou Helen Gika Georgios Theodoridis #metabololomics, #biomarkers, #analyticalchemistry,

Last week in Thessaloniki, I participated in a training led by Lukas Kopecky, Tim Ebbels, Elizabeth Want, and Cecilia Wieder, from the Imperial College London. We had amazing discussions about #metabolomics, #omics integration, #computational tools like MAMSI (https://lnkd.in/eZiTKcfv), and pathway analysis. 👩🔬 👨💻   Thanks to them, all the participants, and especially the Greek institutions who held the training: BiACEM and BIOMIC AUTH. 

The BiACEM project proceeds in good pace. A number of tutorials and peer to peer sessions on #computational #metabolomics from the Imperial College London partner (Tim Ebbels group) offered new insights on software and strategies for data treatment of MS-based metabolomics data. We learned a lot from our colleagues especially on data fusion approaches while in the breaks we enjoyed great views of Mountain Olympus and the Thessaloniki gulf. #LCMS, #statistics, #lifesciences #biomarker #seminar #tutorial #dataanalysis #datascience

We had a full house in our BiACEM open day seminar on Omics Data Analysis. A gathering of different expertise (#LCMS, #computation, #statistics, #lifesciences and others) in the speakers and the audience.  Great presentations from our partners/visitors from the Imperial College London (Tim Ebbels, Elizabeth Want, Lukas Kopecky, Cecilia Wieder) and from Michalis Aivaliotis from AUTh. Many thanks also to our leading clinical medicine partners (professors Manolis Roilides, M. Tsolaki, Marina Boziki) that presented needs and questions in #disease #biomarkers discovery via #metabolomics from a clinical perspective.

There is still time to register for the free 1-day on-site seminar on computational metabolomics. Tuesday 10th September 09.30-15.00 at BIOMIC AUTH in Thessaloniki. Registration link: https://lnkd.in/dE-2jzci Georgios Theodoridis Helen Gika We look forward to see you! #metabolomics #statisticalanalysis #machinelearning #dataanalysis #multiomics #omics #massspectrometry #lcms #education #training #seminar #workshop #analyticalchemistry #biomarkers #systemsbiology Aristotle University of Thessaloniki (AUTH)

There is still time to register for the free 1-day on-site seminar on computational metabolomics. Tuesday 10th September 09.30-15.00 at BIOMIC AUTH in Thessaloniki. Registration link: https://lnkd.in/dE-2jzci Georgios Theodoridis Helen Gika We look forward to see you! #metabolomics #statisticalanalysis #machinelearning #dataanalysis #multiomics #omics #massspectrometry #lcms #education #training #seminar #workshop #analyticalchemistry #biomarkers #systemsbiology Aristotle University of Thessaloniki (AUTH)