Dolomite Microfluidics

🔬 𝗜𝗻𝘀𝘁𝗮𝗹𝗹𝗮𝘁𝗶𝗼𝗻 𝗨𝗽𝗱𝗮𝘁𝗲!🔬 We’re pleased to showcase one of Charlotte Kirkham’s latest installations from October 2024. While some of her recent ones remain confidential at the request of our valued clients, we’re able to offer a behind-the-scenes look at her work in progress. 🌿 This installation, within the agricultural science field, features the 𝗗𝗼𝗹𝗼𝗺𝗶𝘁𝗲 𝗠𝗶𝘁𝗼𝘀 𝗦𝘆𝘀𝘁𝗲𝗺, engineered to support a wide range of applications, with a particular focus on polymeric particles like PLGA and liposome formation. At Dolomite Microfluidics, we take pride in our team’s dedication to innovation and delivering tailored solutions that empower our clients to achieve their goals with confidence. 👏 https://lnkd.in/eKDJgjzY #AgriculturalScience #PolymericParticles #ScientificInnovation #Microfluidics #ResearchAndDevelopment #Teamwork #PLGA #Liposome #Microparticles

🔬 𝗣𝗟𝗚𝗔 𝗕𝗲𝗮𝗱 𝗦𝘆𝗻𝘁𝗵𝗲𝘀𝗶𝘀 𝗨𝘀𝗶𝗻𝗴 𝗗𝗼𝗹𝗼𝗺𝗶𝘁𝗲 𝗠𝗶𝘁𝗼𝘀 𝗦𝘆𝘀𝘁𝗲𝗺! We are excited to share some fascinating results from our recent work with the 𝗗𝗼𝗹𝗼𝗺𝗶𝘁𝗲 𝗠𝗶𝘁𝗼𝘀 𝗦𝘆𝘀𝘁𝗲𝗺 and the 𝗣𝗟𝗚𝗔 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗣𝗮𝗰𝗸𝗮𝗴𝗲. We successfully synthesized uniform PLGA beads, which were then imaged using Scanning Electron Microscopy (SEM). 🎥 Check out the attached video to see these beads in various sizes, ranging from 2 to 75 µm in diameter with each image featuring a 10 µm scale bar for reference. 𝗣𝗟𝗚𝗔 (𝗣𝗼𝗹𝘆(𝗹𝗮𝗰𝘁𝗶𝗰-𝗰𝗼-𝗴𝗹𝘆𝗰𝗼𝗹𝗶𝗰 𝗮𝗰𝗶𝗱)) is a key material in drug delivery, tissue engineering, and other biomedical applications due to its 𝗯𝗶𝗼𝗱𝗲𝗴𝗿𝗮𝗱𝗮𝗯𝗶𝗹𝗶𝘁𝘆 and 𝗯𝗶𝗼𝗰𝗼𝗺𝗽𝗮𝘁𝗶𝗯𝗶𝗹𝗶𝘁𝘆. Our work opens new doors for 𝘀𝗰𝗮𝗹𝗮𝗯𝗹𝗲, 𝗵𝗶𝗴𝗵-𝗽𝗿𝗲𝗰𝗶𝘀𝗶𝗼𝗻 production of PLGA microparticles, providing tighter control over bead size and quality. 🔧 The 𝗗𝗼𝗹𝗼𝗺𝗶𝘁𝗲 𝗠𝗶𝘁𝗼𝘀 𝗦𝘆𝘀𝘁𝗲𝗺 has been instrumental in achieving consistent, high-quality bead synthesis, making it a great tool for advancing research in these areas. 📄🔗https://lnkd.in/eUeE3K_u Stay tuned for more updates: https://lnkd.in/eKDJgjzY #PLGA #Microfluidics #BeadSynthesis #SEM #BiomedicalResearch #Biotechnology #DrugDelivery #DolomiteMitos #Microparticles

🎉 𝗗𝗼𝗹𝗼𝗺𝗶𝘁𝗲 𝗗𝗶𝗿𝗲𝗰𝘁𝗼𝗿 𝗥𝗶𝗰𝗵𝗮𝗿𝗱 𝗚𝗿𝗮𝘆 𝘁𝗼 𝗣𝗿𝗲𝘀𝗲𝗻𝘁 𝗮𝘁 𝗠𝗜𝗧 𝗺𝗶𝗰𝗿𝗼𝗳𝗹𝘂𝗶𝗱𝗶𝗰𝘀 𝗖𝗼𝘂𝗿𝘀𝗲! 🎉 We are thrilled to announce that Richard Gray, Director of Dolomite Microfluidics, will once again deliver a guest lecture as part of Prof. Patrick Doyle’s Microfluidics course at the 𝗠𝗮𝘀𝘀𝗮𝗰𝗵𝘂𝘀𝗲𝘁𝘁𝘀 𝗜𝗻𝘀𝘁𝗶𝘁𝘂𝘁𝗲 𝗼𝗳 𝗧𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆 (𝗠𝗜𝗧)!💡 On 𝗢𝗰𝘁𝗼𝗯𝗲𝗿 𝟭𝟳𝘁𝗵, 𝟮𝟬𝟮𝟰, Richard will present on the 𝗴𝗲𝗻𝗲𝗿𝗮𝗹 𝗽𝗿𝗶𝗻𝗰𝗶𝗽𝗹𝗲𝘀 𝗼𝗳 𝗽𝗮𝗿𝘁𝗶𝗰𝗹𝗲 𝗴𝗲𝗻𝗲𝗿𝗮𝘁𝗶𝗼𝗻 𝗶𝗻 𝗺𝗶𝗰𝗿𝗼𝗳𝗹𝘂𝗶𝗱𝗶𝗰𝘀, a field that is driving innovation across industries like 𝗽𝗵𝗮𝗿𝗺𝗮𝗰𝗲𝘂𝘁𝗶𝗰𝗮𝗹𝘀, 𝗯𝗶𝗼𝘁𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆, 𝗮𝗻𝗱 𝗺𝗮𝘁𝗲𝗿𝗶𝗮𝗹𝘀 𝘀𝗰𝗶𝗲𝗻𝗰𝗲. This is a fantastic opportunity for students and faculty to gain insights into how microfluidics is enabling breakthroughs in areas such as 𝗱𝗿𝘂𝗴 𝗱𝗲𝗹𝗶𝘃𝗲𝗿𝘆 and 𝗱𝗶𝗮𝗴𝗻𝗼𝘀𝘁𝗶𝗰 𝘁𝗼𝗼𝗹𝘀.🌍🔬 For more details about Dolomite Microfluidics and our work in the field, visit our website: https://lnkd.in/eDWhSKxj or https://lnkd.in/eedymvQ4 #microfluidics #innovation #biotechnology #MIT #pharmaceuticals #particlegeneration #DolomiteMicrofluidics #STEM #research

🚀 𝗢𝗽𝘁𝗶𝗺𝗶𝘇𝗶𝗻𝗴 𝗣𝗟𝗚𝗔 𝗣𝗮𝗿𝘁𝗶𝗰𝗹𝗲 𝗦𝘆𝗻𝘁𝗵𝗲𝘀𝗶𝘀 𝘄𝗶𝘁𝗵 𝗗𝗼𝗹𝗼𝗺𝗶𝘁𝗲 𝟯𝗗 𝗙𝗹𝗼𝘄 𝗙𝗼𝗰𝘂𝘀𝗶𝗻𝗴 𝗖𝗵𝗶𝗽𝘀 💡 Dolomite’s 3D Flow Focusing Chips provide precise control over droplet and particle size for PLGA synthesis. Available in two PLGA application packs, they feature junction sizes from 30 µm to 170 µm. 🔹 𝗞𝗲𝘆 𝗕𝗲𝗻𝗲𝗳𝗶𝘁𝘀: The unique pore structure prevents fouling at the junction, ensuring consistent and reliable droplet production over long periods. 💡 𝗪𝗵𝘆 𝗖𝗵𝗶𝗽 𝗦𝗶𝘇𝗲 𝗠𝗮𝘁𝘁𝗲𝗿𝘀: The chip’s junction size directly influences droplet and particle size: 𝟭𝟳𝟬 µ𝗺 𝗰𝗵𝗶𝗽: Droplets (89-180 µm), Particles (20-75 µm) 𝟭𝟬𝟬 µ𝗺 𝗰𝗵𝗶𝗽: Droplets (40-105 µm), Particles (5-39 µm) 𝟲𝟱 µ𝗺 𝗰𝗵𝗶𝗽: Droplets (10-50 µm), Particles (2-19 µm) 𝟯𝟬 µ𝗺 𝗰𝗵𝗶𝗽: Droplets (6-25 µm), Particles (1-7 µm) These chips allow for fine-tuned control, perfect for tailoring particle characteristics to meet specific application needs. 🔗 Read more: https://lnkd.in/eUeE3K_u #PLGA #Microfluidics #DrugDelivery #Biomaterials #ParticleSynthesis #Droplets #3DFlowFocusingChips

🎉 𝗚𝗲𝘁 𝗿𝗲𝗮𝗱𝘆 𝘁𝗼 𝗦𝗠𝗜𝗟𝗘, 𝗯𝗲𝗰𝗮𝘂𝘀𝗲 𝘁𝗼𝗺𝗼𝗿𝗿𝗼𝘄 𝗶𝘀 𝗪𝗼𝗿𝗹𝗱 𝗦𝗺𝗶𝗹𝗲 𝗗𝗮𝘆! 😁💥 At Dolomite Microfluidics, we’re not just innovating - we’re leading the way with groundbreaking products, unmatched support, and a passion for pushing the limits of microfluidic technology! 🚀 And we do it all with a smile on our faces and positivity that’s contagious. 😄🎈 Join us tomorrow in celebrating World Smile Day by spreading joy, kindness, and, of course, a smile! Let’s make the world a happier place, one smile at a time. https://lnkd.in/eKDJgjzY #WorldSmileDay #SpreadSmiles #PositiveVibes #TeamWork #SmilesAllAround #Microfluidics #Innovation

🚨 𝗖𝗼𝗺𝗽𝗿𝗲𝗵𝗲𝗻𝘀𝗶𝘃𝗲 𝗦𝘁𝘂𝗱𝘆 𝗼𝗻 𝗗𝗿𝗼𝗽𝗹𝗲𝘁 𝗥𝗲𝗴𝗶𝗺𝗲𝘀 𝗨𝘀𝗶𝗻𝗴 𝗗𝗼𝗹𝗼𝗺𝗶𝘁𝗲 𝗠𝗶𝗰𝗿𝗼𝗳𝗹𝘂𝗶𝗱𝗶𝗰𝘀! 🚨 We are pleased to share that researchers Nina Kovalchuk, Masanobu Sagisaka, Kasparas Steponavicius, Daniele Vigolo and Mark Simmons from the University of Birmingham have independently characterized Dolomite's microfluidic droplet chips in their study, published in 𝘔𝘪𝘤𝘳𝘰𝘧𝘭𝘶𝘪𝘥𝘪𝘤𝘴 𝘢𝘯𝘥 𝘕𝘢𝘯𝘰𝘧𝘭𝘶𝘪𝘥𝘪𝘤𝘴. Their research offers in-depth insights into droplet generation dynamics, particularly focusing on the transitions between dripping and jetting regimes, highlighting the exceptional flexibility and precision of Dolomite’s microfluidic technology for various droplet-based applications. 📄 Learn more: https://lnkd.in/eNZuSXTJ and https://lnkd.in/e5VVU9ve #Microfluidics #DropletGeneration #DropletRegime #DolomiteMicrofluidics

💡 𝗣𝗟𝗚𝗔 𝗕𝗲𝗮𝗱 𝗙𝗼𝗿𝗺𝗮𝘁𝗶𝗼𝗻: 𝗔 𝗦𝗶𝗺𝗽𝗹𝗲 𝟯-𝗦𝘁𝗲𝗽 𝗣𝗿𝗼𝗰𝗲𝘀𝘀💡 PLGA microparticles are essential for biomedical applications like drug delivery and tissue engineering. Here’s how PLGA beads are formed using the 𝗗𝗼𝗹𝗼𝗺𝗶𝘁𝗲 𝗠𝗶𝘁𝗼𝘀 𝗦𝘆𝘀𝘁𝗲𝗺: 🔹 𝟭. 𝗗𝗿𝗼𝗽𝗹𝗲𝘁 𝗙𝗼𝗿𝗺𝗮𝘁𝗶𝗼𝗻: PLGA droplets are created in the Mitos System using ethyl acetate (EtOAc) as the solvent, encapsulated in Dolomite’s Aqua-Phase. 🔹 𝟮. 𝗦𝗼𝗹𝘃𝗲𝗻𝘁 𝗗𝗶𝗳𝗳𝘂𝘀𝗶𝗼𝗻: As the droplets travel, ethyl acetate diffuses into the surrounding water (~8% in the aqueous fluid. 🔹 𝟯. 𝗦𝗼𝗹𝗶𝗱𝗶𝗳𝗶𝗰𝗮𝘁𝗶𝗼𝗻: Once ethyl acetate is fully removed, the PLGA droplets solidify into uniform beads suspended in the aqueous fluid. This microfluidic approach ensures precise control over droplet size and particle formation, making it ideal for scalable biomedical applications. 🔗 Read more: https://lnkd.in/eUeE3K_u #PLGA #Microfluidics #DrugDelivery #TissueEngineering #Biomaterials #Microparticle #Beads

🌍 𝗛𝗼𝗻𝗼𝗿𝗶𝗻𝗴 𝘁𝗵𝗲 𝗜𝗻𝘁𝗲𝗿𝗻𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗗𝗮𝘆 𝗼𝗳 𝗣𝗲𝗮𝗰𝗲 🕊️ As we reflect on this past weekend’s International Day of Peace (September 21), we at Dolomite Microfluidics reaffirm our belief that innovation and science are essential tools in addressing some of the world’s most pressing challenges. From advancing healthcare through revolutionary diagnostics to facilitating the development of groundbreaking treatments, our cutting-edge microfluidic technology is about more than just innovation - it’s about fostering collaboration, improving lives, and promoting a healthier, more harmonious future for all. Together, let’s continue to innovate for a brighter, more peaceful tomorrow. 🌟 https://lnkd.in/eDWhSKxj #InternationalDayOfPeace #WorldPeaceDay #DolomiteMicrofluidics #MicrofluidicsForGood #Sustainability #GlobalInnovation #HealthcareInnovation

📘 𝗝𝘂𝘀𝘁 𝗥𝗲𝗹𝗲𝗮𝘀𝗲𝗱: 𝗗𝗼𝗹𝗼𝗺𝗶𝘁𝗲’𝘀 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗡𝗼𝘁𝗲 𝗼𝗻 𝗣𝗟𝗚𝗔 𝗣𝗮𝗿𝘁𝗶𝗰𝗹𝗲 𝗦𝘆𝗻𝘁𝗵𝗲𝘀𝗶𝘀 🚀 Looking to enhance drug delivery, tissue engineering, gene therapy, or vaccine development? 🎯 Poly(lactic-co-glycolic acid) (PLGA) is widely known for its biocompatibility, biodegradability, and versatility, making it ideal for biomedical applications. However, Dolomite’s cutting-edge 𝗠𝗶𝘁𝗼𝘀 𝗦𝘆𝘀𝘁𝗲𝗺 with 𝗣𝗟𝗚𝗔 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗣𝗮𝗰𝗸𝘀 takes PLGA to the next level, offering unmatched control over microparticle production, ensuring uniformity and precision for superior therapeutic outcomes. Now researchers can: ✅ Achieve consistent particle size for predictable pharmacokinetics. ✅ Tailor particles for controlled drug release, vaccine efficacy, and tissue engineering. ✅ Scale up production with automated, robust operations. 🆕 Learn more about how the Dolomite Mitos System is advancing biomedical applications in our latest application note! 📄🔗 https://lnkd.in/eUeE3K_u #Microfluidics #DrugDelivery #PLGA #BiomedicalResearch #Innovation #Dolomite #Therapeutics #GeneTherapy #TissueEngineering

✨ 𝗣𝗶𝗼𝗻𝗲𝗲𝗿𝗶𝗻𝗴 𝗣𝗿𝗲𝗰𝗶𝘀𝗶𝗼𝗻 𝘄𝗶𝘁𝗵 𝗗𝗼𝗹𝗼𝗺𝗶𝘁𝗲 𝗠𝗶𝗰𝗿𝗼𝗳𝗹𝘂𝗶𝗱𝗶𝗰𝘀 Proud to share this breakthrough in double emulsion generation using Dolomite's cutting-edge Mitos System! 🔬 In this example, we're able to generate perfectly uniform droplets, where each droplet is double-emulsified by leveraging the jet regime during the initial droplet formation stage. The precision of this system allows for robust control over the size, composition, and encapsulation of droplets, making it ideal for applications in drug delivery, material science, gene & cell therapy, and more. The visual speaks for itself - look at those perfectly formed double emulsions! 🎯🔁 https://lnkd.in/eDWhSKxj #Microfluidics #Dolomite #DoubleEmulsion #DropletGeneration #JetRegime #Innovation #PrecisionEngineering #LabOnAChip