Wellcome/ CRUK Gurdon Institute

📢 We are recruiting a friendly, flexible and highly numerate Finance/Accounts Assistant to join our admin team. The successful candidate will have excellent organisational skills and experience working in accounts, ideally in a laboratory-based environment: https://lnkd.in/eDscvjh4

We're growing again! Computational biologist needed to support diverse neuro drug discovery projects - including functional genomics and small molecule screens in human stem cell models of Alzheimer's and other neurodegenerative diseases.

🤩 Thrilled to see our work on murine oesophageal #Epithelioids published in Nature Genetics, after many years of hard work alongside Albert Herms during our postdoc at Phil Jones' lab Wellcome Sanger Institute and built on the foundational work by Maria P. Alcolea https://lnkd.in/dB2ZckY9 …further developed at Antoran lab at Wellcome/ CRUK Gurdon Institute University of Cambridge, Instituto de Investigación Sanitaria Aragón - IIS Aragón, ARAID administracion, this technique paves the way for new discoveries in #stemcell biology, making research with primary epithelial cells more accessible than ever before. Epithelioids harness the #regenerative capacity of the original tissue to create 3D cultures that maintain proliferation, differentiation and cell density, closely mimicking in vivo tissue dynamics and structure, while keeping genomic stability for up to a year. Thanks to its spectacular expansion capabilities, reduced costs and flexibility, mouse oesophageal Epithelioids greatly impact #3Rs by reducing the number of mice needed in research. Epithelioids enable the study of #epithelial-immune crosstalk by co-culturing with #immune cells. These cells infiltrate and differentiate, partially mimicking the immune landscape of the original tissue. This extensive work over the years was made possible thanks to the support from various funding bodies and institutions: Wellcome Trust, Wellcome Sanger Institute, Cancer Research UK (CRUK), CRUK-RadNet-Cambridge Wellcome/ CRUK Gurdon Institute, University of Cambridge, National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), Instituto de Investigación Sanitaria Aragón - IIS Aragón, ARAID administracion, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) and Cambridge Stem Cell Institute. Huge thanks to Phil (Prof. Philip Jones Wellcome Sanger Institute) for his unwavering support, the freedom to work independently in an exceptional environment with an outstanding team, and his passion for science, which has always inspired us. #Bonustrack at Antoranlab Wellcome/ CRUK Gurdon Institute and Instituto de Investigación Sanitaria Aragón - IIS Aragón, we’ve developed further Epithelioids to study how #environment affects #mutant #landscape in humans and to model #tumour #evolution and tissue #toxicity during clinical treatments. Exciting findings on the way. Stay tuned!

Join us at the Mercia Stem Cell Alliance 12th annual conference on 12 December at Aston University. Looking forward to the keynote by Wellcome/ CRUK Gurdon Institute's Emma Rawlins, sharing our lab's story on HIF activation in MPNs, and seeing all the fantastic ECR posters and talks. https://lnkd.in/et2_RqNx

Exciting Job Opportunity: We are looking for a postdoc with a strong interest in epigenetics and transcription regulation to join my new lab at the University of Warwick. This BBSRC-funded position is focused on studying transcription factor networks that mediate human germline development. For further details, please see the description below. Application deadline: 24th November 2024 To apply please follow:  https://lnkd.in/eF-WmD4p If you have any questions, don’t hesitate to contact me at Wolfram.Gruhn@warwick.ac.uk.

Don't miss the feature and video that explore Prof Azim Surani’s fundamental contribution to mammalian epigenetic inheritance and gene regulation.

I am very happy to share that my first article just came out! Thanks to joining the forces of VIB, The Netherlands Cancer Institute and Wellcome/ CRUK Gurdon Institute, we were able to show how natural processes occurring in the breast can influence cancer progression among women carrying Brca1 mutation. Big congratulations to my co-authors Hendrik Messal and Hristina Hristova and the supervisors of this project Colinda Scheele, Jacco van Rheenen and Benjamin D. Simons. Thank you and have a good reading session! https://lnkd.in/dhk-sejy

Join us at the Mercia Stem Cell Alliance 12th annual conference on 12 December at Aston University. Looking forward to the keynote by Wellcome/ CRUK Gurdon Institute's Emma Rawlins, sharing our lab's story on HIF activation in MPNs, and seeing all the fantastic ECR posters and talks. https://lnkd.in/et2_RqNx

📣Mark your calendars for our next #talk 🤩 📌Topic: Epithelioids: A novel long-term 3D culture system to study tissue behaviour 🎙️Speaker: Dr David Fernandez-Antoran, from the Gurdon Institute, UK and IIS-Aragon, Spain. 🗓️Date and time: 10 October 2024, 19:00 (CET) 🔗 Scan the QR code or follow the link for registration: https://lnkd.in/dk6ZCwGs ➡ Read more on Network: https://lnkd.in/dzxeGE7A ✅ #Academictalk is organized by the Junior Section of the Spanish Society of Biochemistry and Molecular Biology, SEBBM, in the framework of the FEBS Junior Section initiative #FEBS_JS #YoungFEBS #FEBSJuniorSection #onlinetalk #talkseries, #SEBBMJuniorSection, #Biochemistry #3Dcellculture #Epithelioids #Lifesciences

I am so pleased that the Lyme Resource Centre Lyme disease experience survey 2024 summary posters have now been accepted and published in #ResearchDirections #OneHealth Cambridge University Press . The survey responses highlight missed opportunities for diagnosis and treatment of #Lymedisease and the need for more support for those with the disease. Please do have a read and spread the word. #Tickawareness #Tickbiteprevention #Lymediseaseawareness