Immuno-oncology Insights

The preclinical journey: transitioning a novel #celltherapy into early phase #clinicaltrials In this #interview with Silvio Manfredo-Vieira (Associate Director for Correlative and Translational Studies at the Department of Dermatology, University of Pennsylvania), he discusses his role directing the translational research to move novel cell therapies from the lab into early phase clinical trials and pioneering a chimeric auto-#antibodyreceptor to target B-cell-mediated diseases. Read this interview below:

#Webinar now available on demand! Same-section spatial #multiomics: a platform for detailed analysis of the #solidtumor TME While #spatialbiology can help to better understand the #TME, current technologies are unable to simultaneously capture protein and #RNA information within the same #histological section. Miltenyi Biotec’s Emily Neil (Manager, Molecular Technologies) and Ariadna Pascual (Global Product Manager) explore technologies that allow for same-section #spatialmultiomics and simultaneous protein and #RNAdetection. Watch at your convenience below:

Same-section spatial multiomics: a platform for detailed analysis of the solid tumor TME While #spatialbiology can help to better understand the #TME, current technologies are unable to simultaneously capture protein and #RNA information within the same #histological section. This month, Miltenyi Biotec’s Emily Neil (Manager, Molecular Technologies) and Ariadna Pascual (Global Product Manager) will explore technologies that allow for same-section #spatialmultiomics and simultaneous protein and #RNAdetection. Attend this webinar to: • Understand a same-section spatial multiomics assay and its advantages for protein and RNA analysis • Discover the applications of same-section spatial RNA and protein detection within I-O • Learn about automated spatial gene expression assay analysis specifically within the solid tumor TME Register for this #webinar below:

#FastFacts now available! #Myeloidcells: unveiling their secrets as #biomarkers through next-generation sample preparation The Curiox Biosystems Laminar Wash™ technology provides improvements in #myeloidcellcharacterization, fostering future research in advanced #flowcytometry, single-cell analysis, and personalized medicine. These advancements aim to unravel myeloid cell complexity, identify biomarkers, enhance disease perspectives, analyze extensive data, and customize immune checkpoint inhibitor therapy for optimal efficacy with minimal side effects View this FastFacts below:

Don't miss out on the March Immuno-oncology Insights issue! Featuring this month's spotlight content: Combination therapy development View below:

Same-section spatial multiomics: a platform for detailed analysis of the solid tumor TME While #spatialbiology can help to better understand the #TME, current technologies are unable to simultaneously capture protein and #RNA information within the same #histological section. This May, Miltenyi Biotec’s Emily Neil (Manager, Molecular Technologies) and Ariadna Pascual (Global Product Manager) will explore technologies that allow for same-section #spatialmultiomics and simultaneous protein and #RNAdetection. Register for this #webinar below:

Don't miss out on the February Immuno-oncology Insights issue! Featuring this month's spotlight content: Assessing the evolving I-O landscape: key challenges and opportunities for 2024 View below:

#Interview now available! Advancing #immunotherapy and data-driven research Read this interview with Jill O’Donnell-Tormey (CEO and Director of Scientific Affairs at the Cancer Research Institute (CRI)), where they discuss the latest developments in data-driven technology for the I-O space. Read below to learn more about: • The importance of basic research in drug development • The current state of the I-O space • The significance of new #biomarkers, such as #circulatingtumorDNA

Don’t miss out on this Immuno-oncology Insights. Spotlight content on: Overcoming mechanisms of tumor resistance part 2. What progress is being made in solid tumors? Read below:

#Webinar now available on demand! CAR-T: Why not me? Featuring Nina Senutovitch (Senior Scientist, Sartorius), Yanping Guo (Flow Cytometry Translational Technology Platform Manager, UCL Cancer Institute), and Sarwish Rafiq (Program Leader for CAR-T Basic/Translational Research, Winship Center for Cancer Immunology), where they discuss how feasible it is to predict the potential of therapies based on patients’ #immunological states. Watch the webinar to: • Learn about the applicability of CAR-T and its variations • Gain insight into adjusting CAR-T to accommodate patients who do not meet eligibility criteria • Explore how #flowcytometry can assist in the research, development, and production of these therapies Watch at your convenience below: