Akoya Biosciences, Inc.

In our lab, we are currently conducting an in-depth investigation into the spatial organization of the TME in large-cell neuroendocrine carcinomas (LCNEC) of the lung (17x marker multiplex panel). Our preliminary findings suggest significant heterogeneity in both the peritumoral bystander cell populations and the immune cell infiltrates, reflecting the diverse clinical responses observed towards immune checkpoint inhibition. Additionally, we observe marked differences in tumor vascularization, ranging from highly perfused tumors to those with diminished angiogenic activity. The integration of these spatial data with clinical outcomes, as well as genetic and transcriptomic profiles from this cohort, will provide critical insights into the underlying biology and therapeutic vulnerabilities of LCNEC. 🔬 🧬 💊 Raban Heller Konrad Steinestel Armin Riecke Akoya Biosciences, Inc.

🌟 Introducing our Rising Stars in Spatial Webinar Series! 🌟  Celebrate the innovative work of scientists advancing spatial proteomics! Each session features researchers harnessing cutting-edge spatial technologies to unravel the tissue microenvironment and uncover the biological systems driving disease. ✨ Featured Rising Stars:  1. Naomi Berrell, Research Assistant, Queensland Spatial Biology Centre (QSBC) 2. Anna Martinez Casals, Ph.D., Researcher, Stanford University, Bioengineering Department  .. and many more to come! 🔬 Kick-off Session: Shaping the Future of Spatial Biology with Niro Ramachandran, Ph.D., Chief Business Officer & Clemens D., Ph.D., Field Applications Manager of Akoya Biosciences, will explore how spatial biology is transforming discoveries with a focus on a groundbreaking 100-plex study on Head and Neck Cancer.  🗓️ Date Thursday, 27th March 2025  ⏰ Time 9am PDT | 12PM EDT | 5PM CET   🔗 Register Now: https://lnkd.in/eJ4YMen6  #TheSpatialBologyCompany #RisingStarsinSpatial #NextGenerationofSpatialScientists #PhenoCyclerFusion #PhenoImagerHT

Very excited to share that our image titled "Periodontal Petals" was selected as a winner of the 2025 Koch Institute Image Awards! This image showcases our efforts to understand the spatial tissue niche changes in periodontitis using spatial proteomics (Codex Phenocycler platform from Akoya Biosciences, Inc. ). Periodontitis is a chronic inflammatory disease that affects almost one in two adults worldwide with no definitive cure and has been associated with diseases like Alzheimers, different cancers, colitis, rheumatoid arthritis and diabetes. We hope our research can help reveal new strategies to target this disease. Huge shoutout to my collaborators Y. W. Stacy Cho , Stephanie Yiu and the incredible mentors of this project Alex K. Shalek , Laura Kiessling , Sizun Jiang Dr. David Kim and Dr. Chia-Yu Chen from MIT Department of Chemistry,MIT Institute for Medical Engineering and Science (IMES), Harvard School of Dental Medicine, Beth Israel Deaconess Medical Center and the Harvard Medical School Its an incredible honor to see our image displayed at the Koch Institute of Integrative Cancer Research at MIT. Looking forward to more exciting updates on this project and amazing collaboration. #MIT #KochInstitute #KImages #BIDMC #HSDM

At the World Immune Regulation Meeting (WIRM) in Davos, organized by the Swiss Institute of Allergy and Asthma Research (SIAF) in such a beautiful location in the Swiss Alps, we are excited to engage in discussions on the application of spatial proteomics in immunology research projects. Join us at the Akoya Biosciences, Inc. booth to tell us about your projects and to discuss what spatial proteomics offers in advancing research and understanding in the field of immunology. #WIRM #Immuneregulation #immunology #spatialbiology #spatialomics

🚨 LUNCH AND LEARN SEMINAR ALERT! 🚨 🔬 Unlock the Power of Spatial Omics for Deeper Biological Insights! Join us on Wednesday, March 19, 2025, from 12 PM – 2 PM at BRT 115, Pelotonia Institute for Immuno-Oncology IMDP, for an exclusive seminar on cutting-edge single-cell spatial proteomics. 🔎 Learn how the PhenoCycler-Fusion enables: ✅ High-plex, single-cell spatial analysis ✅ Fast start-up with pre-optimized panels ✅ Seamless integration with single-cell transcriptomics ✅ Real-world applications across multiple research areas 📢 Don't miss this opportunity to explore how spatial biology is transforming research! 📍 Venue: BRT 115, Pelotonia Institute for Immuno-Oncology IMDP 📅 Date: Wednesday, March 19, 2025 ⏰ Time: 12 PM – 2 PM 🔗 Register now: https://lnkd.in/d7DKhtmX #SpatialBiology #Proteomics #SingleCellAnalysis #ImmunoOncology #PhenoCycler #AkoyaBiosciences #ResearchInnovation

This week’s #TissueTuesday features a multiplex IHC staining of a synovial biopsy from a Rheumatoid Arthritis patient, captured using the Akoya Biosciences, Inc. Phenocycler! 🧬🔬 The image reveals the intricate cellular landscape, with fibroblasts and macrophages in the lining layer, while T cytotoxic, helper, and regulatory cells cluster around the blood vessels.  Stained as part of a 30-plex panel , this image provides valuable insights into the immune interactions driving inflammation. 🌟 #MultiplexIHC #AkoyaPhenoCycler #RheumatoidArthritis #ImmuneCells #Fibroblasts #Macrophages #TCells #CellularInsights 

📍 Today Aurogene Srl and Akoya Biosciences, Inc. at "Spatial OMICS: between challenges and opportunities" hosted by the Università degli Studi di Torino Dusan Zencak will give a presentation on "Spatial Proteomics at Your Scale, from Discovery to the Clinic" For event details, visit: [Event Link](https://lnkd.in/euwjFuT8) #weservescience #spatialbiology #spatialproteomics

🧬 Mardi 11 mars - #Single Cell, #Biologie spatiale, #analyse de data en vedettes à l'IUCT Oncopole Toulouse 🔬 9 des principaux industriels du secteur présenteront et échangeront avec les scientifiques du territoire sur les apports de ces technologies pour faire avancer la recherche sur les #tissus complexes, recueillir des informations cellulaires détaillées et examiner le contexte positionnel des cellules uniques dans un tissu.  10x Genomics  Akoya Biosciences, Inc.  BD  Bruker Spatial Biology Element Biosciences  LevitasBio RareCyte, Inc. Standard BioTools Visiopharm 📌 Et déjà plus de 100 inscrits pour échanger sur ce secteur en plein essor ! 👉 Evénement gratuit sur inscription, réservé aux personnels de laboratoire :  https://lnkd.in/eb6kNyTG #omics #transcriptomique #proétéomique #image analysis

Excited to share that on Monday the 10th of March, I'll be in Torino discussing Spatial Omics solutions. I'll be presenting on "Spatial Proteomics at Your Scale, from Discovery to the Clinic" at the "Spatial OMICS: between challenges and opportunities" event hosted by the University of Torino. For event details, visit: [Event Link](https://lnkd.in/euwjFuT8) #spatialbiology #spatialproteomics Akoya Biosciences, Inc. Aurogene Srl

Announcing the Recipient of the IO60 Spatial Omics Grant Program We are thrilled to announce that Lorena Rosas, PhD, Research Senior Associate, and her mentors, Drs. Mauricio Rojas and Ana L. Mora, from the Department of Internal Medicine at The Ohio State University, have been awarded our IO60 Spatial Omics Grant! Their groundbreaking research will utilize the PhenoCycler®-Fusion 2.0 platform and PhenoCode IO60 panel to analyze key immune cell types, such as NK cells, within IPF lung tissue. Learn more: https://lnkd.in/d2ynPxac Congratulations, Dr. Lorena Rosas and Professors Mauricio Rojas and Ana L. Mora! We look forward to collaborating on this transformative project. Find out how PhenoCycler-Fusion and the PhenoCode IO60 Panel can transform your discoveries, https://lnkd.in/dUA52qAM